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Activation of IL-17 receptor leads to increased oxidative inflammation in peripheral monocytes of autistic children.

artículo científico publicado en 2017

Activation of adenosine A2A receptor signaling regulates the expression of cytokines associated with immunologic dysfunction in BTBR T+ Itpr3tf/J mice.

artículo científico publicado en 2017

Adenosine A2A receptor modulates neuroimmune function through Th17/retinoid-related orphan receptor gamma t (RORγt) signaling in a BTBR T+ Itpr3tf/J mouse model of autism

artículo científico publicado en 2017

Adenosine A2A receptor signaling affects IL-21/IL-22 cytokines and GATA3/T-bet transcription factor expression in CD4+ T cells from a BTBR T+ Itpr3tf/J mouse model of autism.

artículo científico publicado en 2017

CXCR3 antagonist AMG487 suppresses rheumatoid arthritis pathogenesis and progression by shifting the Th17/Treg cell balance

scientific article published on 23 August 2019

DAPTA, a C-C chemokine receptor 5 (CCR5) antagonist attenuates immune aberrations by downregulating Th9/Th17 immune responses in BTBR T+ Itpr3tf/J mice

artículo científico publicado en 2019

Design and Synthesis of N-Arylphthalimides as Inhibitors of Glucocorticoid-Induced TNF Receptor-Related Protein, Proinflammatory Mediators, and Cytokines in Carrageenan-Induced Lung Inflammation.

artículo científico publicado en 2015

Dexrazoxane Averts Idarubicin-Evoked Genomic Damage by Regulating Gene Expression Profiling Associated With the DNA Damage-Signaling Pathway in BALB/c Mice.

artículo científico publicado en 2017

Downregulation in Helios transcription factor signaling is associated with immune dysfunction in blood leukocytes of autistic children.

artículo científico publicado en 2018

Dysregulated enzymatic antioxidant network in peripheral neutrophils and monocytes in children with autism

scientific article published on 23 August 2018

Dysregulation in IL-6 receptors is associated with upregulated IL-17A related signaling in CD4+ T cells of children with autism

scientific article published on 23 October 2019

Dysregulation of T cell immunoglobulin and mucin domain 3 (TIM-3) signaling in peripheral immune cells is associated with immune dysfunction in autistic children

scientific article published on 24 December 2018

Dysregulation of Th1, Th2, Th17, and T regulatory cell-related transcription factor signaling in children with autism.

artículo científico publicado en 2016

Dysregulation of the expression of HLA-DR, costimulatory molecule, and chemokine receptors on immune cells in children with autism

scientific article published on 26 October 2018

Elevated IL-16 expression is associated with development of immune dysfunction in children with autism

artículo científico publicado en 2018

Genetic and epigenetic alterations induced by the small-molecule panobinostat: A mechanistic study at the chromosome and gene levels

artículo científico publicado en 2019

Histamine 4 receptor promotes expression of costimulatory B7.1/B7.2 molecules, CD28 signaling and cytokine production in stress-induced immune responses.

artículo científico publicado en 2015

Imbalance between the anti- and pro-inflammatory milieu in blood leukocytes of autistic children.

artículo científico publicado en 2016

Immune Alterations in CD8(+) T Cells Are Associated with Neuronal C-C and C-X-C Chemokine Receptor Regulation Through Adenosine A2A Receptor Signaling in a BTBR T(+) Itpr3(tf)/J Autistic Mouse Model.

artículo científico publicado en 2017

Increased oxidative stress in the cerebellum and peripheral immune cells leads to exaggerated autism-like repetitive behavior due to deficiency of antioxidant response in BTBR T + tf/J mice

artículo científico publicado en 2018

Inhibition of Bruton's tyrosine kinase and IL-2 inducible T-cell kinase suppresses both neutrophilic and eosinophilic airway inflammation in a cockroach allergen extract-induced mixed granulocytic mouse model of asthma using preventative and therape

artículo científico publicado en 2019

Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in periphery and brain of BTBR T+tf/J mice

artículo científico publicado en 2019

Oxidative and inflammatory mediators are upregulated in neutrophils of autistic children: Role of IL-17A receptor signaling

artículo científico publicado en 2018

Protection by tyrosine kinase inhibitor, tyrphostin AG126, through the suppression of IL-17A, RORγt, and T-bet signaling, in the BTBR mouse model of autism

scientific article published on 30 August 2018

Regulation of TNF-α and NF-κB activation through the JAK/STAT signaling pathway downstream of histamine 4 receptor in a rat model of LPS-induced joint inflammation.

artículo científico publicado en 2015

Resveratrol Ameliorates Dysregulation of Th1, Th2, Th17, and T Regulatory Cell-Related Transcription Factor Signaling in a BTBR T + tf/J Mouse Model of Autism

artículo científico publicado en 2016

Resveratrol Improves Neuroimmune Dysregulation Through the Inhibition of Neuronal Toll-Like Receptors and COX-2 Signaling in BTBR T+ Itpr3tf/J Mice

artículo científico publicado en 2018

Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T+ Itpr3tf/J autistic mice.

artículo científico publicado en 2018

Resveratrol treatment attenuates chemokine receptor expression in the BTBR T+tf/J mouse model of autism

artículo científico publicado en 2016

S3I-201, a selective Stat3 inhibitor, restores neuroimmune function through upregulation of Treg signaling in autistic BTBR T+ Itpr3tf/J mice

artículo científico publicado en 2018

STA-21, a STAT-3 inhibitor, attenuates the development and progression of inflammation in collagen antibody-induced arthritis.

artículo científico publicado en 2016

Systemic inflammation in asocial BTBR T+ tf/J mice predisposes them to increased psoriatic inflammation.

artículo científico publicado en 2017

The PPARδ agonist GW0742 restores neuroimmune function by regulating Tim-3 and Th17/Treg-related signaling in the BTBR autistic mouse model

scientific article published on 15 September 2018

The Stat3 inhibitor, S3I-201, downregulates lymphocyte activation markers, chemokine receptors, and inflammatory cytokines in the BTBR T+ Itpr3tf/J mouse model of autism

scientific article published on 09 July 2019

The histamine-4 receptor antagonist JNJ7777120 prevents immune abnormalities by inhibiting RORγt/T-bet transcription factor signaling pathways in BTBR T+ Itpr3tf/J mice exposed to gamma rays

artículo científico publicado en 2019

The potent immunomodulatory compound VGX-1027 regulates inflammatory mediators in CD4+ T cells, which are concomitant with the prevention of neuroimmune dysregulation in BTBR T+ Itpr3tf/J mice

artículo científico publicado en 2019

The tyrosine kinase inhibitor tyrphostin AG126 reduces activation of inflammatory cells and increases Foxp3+ regulatory T cells during pathogenesis of rheumatoid arthritis.

artículo científico publicado en 2016

Toll-like receptor 4 signaling is associated with upregulated NADPH oxidase expression in peripheral T cells of children with autism.

artículo científico publicado en 2016

Toll-like receptors, NF-κB, and IL-27 mediate adenosine A2A receptor signaling in BTBR T+ Itpr3tf/J mice

artículo científico publicado en 2017

Upregulation of IL-9 and JAK-STAT signaling pathway in children with autism.

artículo científico publicado en 2017

Upregulation of peripheral CXC and CC chemokine receptor expression on CD4+ T cells is associated with immune dysregulation in children with autism

artículo científico publicado en 2017

Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells

artículo científico publicado en 2016

β-1,3-Glucan reverses aflatoxin B1-mediated suppression of immune responses in mice

artículo científico publicado en 2016