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An alteration of human immunodeficiency virus gp41 leads to reduced CCR5 dependence and CD4 independence

artículo científico publicado en 2008

An immunoglobulin fusion protein based on the gp120-CD4 receptor complex potently inhibits human immunodeficiency virus type 1 in vitro

artículo científico publicado en 2006

Antibodies to CD4-induced sites in HIV gp120 correlate with the control of SHIV challenge in macaques vaccinated with subunit immunogens

artículo científico publicado en 2007

Antibody persistence and T-cell balance: two key factors confronting HIV vaccine development

artículo científico publicado en 2014

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

artículo científico publicado en 2012

Antigenic properties of the HIV envelope on virions in solution

artículo científico publicado en 2013

Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cells

artículo científico publicado en 2015

Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion

artículo científico publicado en 2002

Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection

artículo científico publicado en 2015

CCR5 density levels on primary CD4 T cells impact the replication and Enfuvirtide susceptibility of R5 HIV-1.

artículo científico publicado en 2007

CD4-induced epitopes in the HIV envelope glycoprotein, gp120.

artículo científico publicado en 2007

Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1

artículo científico publicado en 2015

Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1

artículo científico publicado en 2015

Conserved molecular signatures in gp120 are associated with the genetic bottleneck during simian immunodeficiency virus (SIV), SIV-human immunodeficiency virus (SHIV), and HIV type 1 (HIV-1) transmission

artículo científico publicado en 2015

Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a "stochastic" process

artículo científico publicado en 2017

Control of HIV-1 infection by soluble factors of the immune response

artículo científico publicado en 2004

Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure

artículo científico publicado en 2002

Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activity.

artículo científico publicado en 2011

Crosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques

artículo científico publicado en 2002

Development of an oral prime-boost strategy to elicit broadly neutralizing antibodies against HIV-1.

artículo científico publicado en 2002

Development of vaccination strategies that elicit broadly neutralizing antibodies against human immunodeficiency virus type 1 in both the mucosal and systemic immune compartments

artículo científico publicado en 2002

Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection

artículo científico publicado en 2009

Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

artículo científico publicado en 2013

Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins

artículo científico publicado en 2015

Epitope target structures of Fc-mediated effector function during HIV-1 acquisition

artículo científico publicado en 2014

Evaluation of -2 RANTES vaginal microbicide formulations in a nonhuman primate simian/human immunodeficiency virus (SHIV) challenge model

artículo científico publicado en 2007

HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques

artículo científico publicado en 2014

HIV-1-suppressive factors are secreted by CD4+ T cells during primary immune responses

artículo científico publicado en 2003

Human Th17 Cells Lack HIV-Inhibitory RNases and Are Highly Permissive to Productive HIV Infection

artículo científico publicado en 2016

Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro

artículo científico publicado en 2005

Identification and Characterization of an Immunogenic Hybrid Epitope Formed by both HIV gp120 and Human CD4 Proteins.

artículo científico publicado en 2012

Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins

artículo científico publicado en 2011

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

artículo científico publicado en 2012

Induction of neutralizing antibodies against human immunodeficiency virus type 1 primary isolates by Gag-Env pseudovirion immunization

artículo científico publicado en 2005

Newcastle Disease Virus Expressing Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Induces Strong Mucosal and Serum Antibody Responses in Guinea Pigs

artículo científico publicado el 17 de agosto de 2011

Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region

artículo científico publicado en 2016

Preclinical evaluation of synthetic -2 RANTES as a candidate vaginal microbicide to target CCR5.

artículo científico publicado en 2006

Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro

artículo científico publicado en 2007

Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands

artículo científico publicado en 2008

Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasma.

artículo científico publicado en 2012

Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNases

artículo científico publicado en 2012

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

artículo científico publicado en 2014

Survivors Remorse: antibody-mediated protection against HIV-1.

artículo científico publicado en 2017

Synergistic Inhibition of R5 HIV-1 by the Fusion Protein (FLSC) IgG1 Fc and Maraviroc in Primary Cells: Implications for Prevention and Treatment

artículo científico publicado en 2015

Synergistic inhibition of R5 HIV-1 by maraviroc and CCR5 antibody HGS004 in primary cells: implications for treatment and prevention

artículo científico publicado el 1 de junio de 2011

Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates

artículo científico publicado en 2015

λ Light Chain Bias Associated With Enhanced Binding and Function of Anti-HIV Env Glycoprotein Antibodies

artículo científico publicado en 2015