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Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat.

artículo científico publicado en 2003

Adding a statin to a combination of ACE inhibitor and ARB normalizes proteinuria in experimental diabetes, which translates into full renoprotection

artículo científico publicado en 2010

Analogs of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects

artículo científico publicado en 2012

Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway

artículo científico publicado en 2013

Beneficial effect of TGFbeta antagonism in treating diabetic nephropathy depends on when treatment is started

Cellular responses to protein overload: key event in renal disease progression

artículo científico publicado en 2004

Combining lisinopril and l-arginine slows disease progression and reduces endothelin-1 in passive Heymann nephritis

artículo científico publicado en 2003

Cyclin-dependent kinase inhibition limits glomerulonephritis and extends lifespan of mice with systemic lupus

scholarly article by Carla Zoja et al published 2007 in Arthritis and Rheumatism

Disruption of the Ang II type 1 receptor promotes longevity in mice

artículo científico publicado en 2009

Distinct cardiac and renal effects of ETA receptor antagonist and ACE inhibitor in experimental type 2 diabetes

artículo científico publicado en 2011

Effect of combining ACE inhibitor and statin in severe experimental nephropathy

artículo científico publicado en 2002

Effects of rosuvastatin on glomerular capillary size-selectivity function in rats with renal mass ablation

artículo científico publicado en 2007

How to fully protect the kidney in a severe model of progressive nephropathy: a multidrug approach

artículo científico publicado en 2002

Human Bone Marrow Mesenchymal Stem Cells Accelerate Recovery of Acute Renal Injury and Prolong Survival in Mice

scholarly article by Marina Morigi et al published August 2008 in Stem Cells

In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies

artículo científico publicado en 2005

Involvement of renal tubular Toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus

artículo científico publicado en 2007

Life-sparing effect of human cord blood-mesenchymal stem cells in experimental acute kidney injury

artículo científico publicado en 2010

Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy

artículo científico publicado en 2012

Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure

artículo científico publicado en 2004

Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides

artículo científico publicado en 2008

Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor kappaB- and p38 mitogen-activated protein kinase-dependent pathways

artículo científico publicado en 2003

Protein traffic activates NF-kB gene signaling and promotes MCP-1–dependent interstitial inflammation

article

Shigatoxin-induced endothelin-1 expression in cultured podocytes autocrinally mediates actin remodeling

artículo científico publicado en 2006

Targeted deletion of angiotensin II type 1A receptor does not protect mice from progressive nephropathy of overload proteinuria

artículo científico publicado en 2004

Unlike each drug alone, lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes

artículo científico publicado en 2009

Vasopeptidase inhibitor restores the balance of vasoactive hormones in progressive nephropathy

artículo científico publicado en 2004

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