Lista de obras -

5-fluorouracil administered as a 48-hour chronomodulated infusion in combination with leucovorin and cisplatin: a randomized phase II study in metastatic colorectal cancer.

artículo científico publicado en 2001

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

artículo científico publicado en 2008

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

artículo científico publicado en 2008

A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

artículo científico publicado en 2008

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

artículo científico publicado en 2006

A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

artículo científico publicado en 2004

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

artículo científico publicado en 2010

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

artículo científico publicado en 2009

Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

artículo científico publicado en 2001

An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

artículo científico publicado en 2004

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

artículo científico publicado en 1999

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

artículo científico publicado en 2002

Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.

artículo científico publicado en 2002

Chronic administration of suramin induces neurotoxicity in rats.

artículo científico publicado en 1997

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

artículo científico publicado en 1996

Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer.

artículo científico publicado en 2009

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

artículo científico publicado en 2013

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

scientific article published on 24 July 2013

Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

artículo científico publicado en 2008

Differential affinities of AF-DX 116, atropine and pirenzepine for muscarinic receptors of guinea pig gastric fundus, atria and urinary bladder: might atropine distinguish among muscarinic receptor subtypes?

artículo científico publicado en 1990

Discordant somatic and germlineVEGF-Agenotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis

artículo científico publicado en 2009

Drug therapeutic failures in emergency department patients. A university hospital experience.

artículo científico publicado en 2004

Genotype A1/A2 associated with neuroleptic malignant syndrome.

artículo científico publicado en 2005

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

artículo científico publicado en 2005

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

artículo científico publicado en 2006

Infusions of fluorouracil and leucovorin: effects of the timing and semi-intermittency of drug delivery

scientific article published on 01 October 1999

Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

artículo científico publicado en 2001

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

scientific article published on 01 January 1999

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

artículo científico publicado en 2006

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

artículo científico publicado en 2011

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

artículo científico publicado en 2009

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

artículo científico publicado en 2002

Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role

artículo científico publicado en 1993

Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens.

artículo científico publicado en 1999

Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.

artículo científico publicado en 2009

Periodontal tissue disposition of azithromycin

scientific article published on 01 December 1997

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

artículo científico publicado en 2001

Pharmacokinetic optimisation of the treatment of cancer with high dose zidovudine.

artículo científico publicado en 1998

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

artículo científico publicado en 2002

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

artículo científico publicado en 2008

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

artículo científico publicado en 2002

Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

artículo científico publicado en 2002

Synergistic antiproliferative activity of suramin and alpha 2A-interferon against human colorectal adenocarcinoma cell lines: in vitro studies.

artículo científico publicado en 1994

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

artículo científico publicado en 2006

Time-Dependent Pharmacokinetics of 5-Fluorouracil and Association With Treatment Tolerability in the Adjuvant Setting of Colorectal Cancer

artículo científico publicado en 2011

Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia

scientific article published on 01 August 2000

[A selective antimuscarinic agent: pirenzepine. Review of its pharmacologic and clinical properties]

scientific article published on 01 July 1989

[The physiopathological aspects of the atrial natriuretic factor]

scientific article published on 01 April 1992

Lista de obras de

5-fluorouracil administered as a 48-hour chronomodulated infusion in combination with leucovorin and cisplatin: a randomized phase II study in metastatic colorectal cancer.

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.

Chronic administration of suramin induces neurotoxicity in rats.

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer.

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

Differential affinities of AF-DX 116, atropine and pirenzepine for muscarinic receptors of guinea pig gastric fundus, atria and urinary bladder: might atropine distinguish among muscarinic receptor subtypes?

Discordant somatic and germlineVEGF-Agenotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis

Drug therapeutic failures in emergency department patients. A university hospital experience.

Genotype A1/A2 associated with neuroleptic malignant syndrome.

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

Infusions of fluorouracil and leucovorin: effects of the timing and semi-intermittency of drug delivery

Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role

Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens.

Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.

Periodontal tissue disposition of azithromycin

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

Pharmacokinetic optimisation of the treatment of cancer with high dose zidovudine.

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

Synergistic antiproliferative activity of suramin and alpha 2A-interferon against human colorectal adenocarcinoma cell lines: in vitro studies.

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

Time-Dependent Pharmacokinetics of 5-Fluorouracil and Association With Treatment Tolerability in the Adjuvant Setting of Colorectal Cancer

Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia

[A selective antimuscarinic agent: pirenzepine. Review of its pharmacologic and clinical properties]

[The physiopathological aspects of the atrial natriuretic factor]