Lista de obras -

A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors

artículo científico publicado en 2007

A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.

artículo científico publicado en 2011

Acute RyR1 Ca<sup>2+</sup> leak enhances NADH-linked mitochondrial respiratory capacity

artículo científico publicado en 2021

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

artículo científico publicado en 2017

Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice

artículo científico publicado en 2006

Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

artículo científico publicado en 2003

Bradycardic therapy improves left ventricular function and remodeling in dogs with coronary embolization-induced chronic heart failure

scientific article published on 02 February 2007

Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.

artículo científico publicado en 2012

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

artículo científico publicado en 2015

Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

artículo científico publicado en 2015

Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice

artículo científico publicado en 2011

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

artículo científico publicado en 2005

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

artículo científico publicado en 2015

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

artículo científico publicado en 2003

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

artículo científico publicado en 2009

Intracellular calcium leak as a therapeutic target for RYR1-related myopathies

scientific article published on 31 March 2020

Late Ventilator-Induced Diaphragmatic Dysfunction After Extubation

scientific article published on 01 October 2020

Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice

artículo científico publicado en 2008

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

artículo científico publicado en 2010

Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.

artículo científico publicado en 2012

Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties.

artículo científico publicado en 2005

Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation

scientific article published on 19 November 2019

Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure.

artículo científico publicado en 2013

Nonshivering thermogenesis protects against defective calcium handling in muscle

scientific article published on 07 August 2008

Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model

artículo científico publicado en 2017

Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization

artículo científico publicado en 2004

PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

artículo científico publicado en 2003

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

artículo científico publicado en 2005

Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice ⬇️

artículo científico publicado el 22 de noviembre de 2010

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits

artículo científico publicado en 2017

Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?

artículo científico publicado en 2002

Protein kinase A and two phosphatases are components of the inositol 1,4,5-trisphosphate receptor macromolecular signaling complex

artículo científico publicado en 2002

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

artículo científico publicado en 2002

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

artículo científico publicado en 2011

Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers

artículo científico publicado en 2002

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity

artículo científico publicado en 2008

Reply from Daniel C. Andersson, Matthew J. Betzenhauser, Steven Reiken, Alisa Umanskaya, Takayuki Shiomi and Andrew R. Marks ⬇️

artículo científico publicado el 15 de junio de 2013

Reply to Eisner et al.: CaMKII phosphorylation of RyR2 increases cardiac contractility.

artículo científico publicado en 2010

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

artículo científico publicado en 2002

Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

artículo científico publicado en 2010

Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice

artículo científico publicado en 2010

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.

artículo científico publicado en 2011

Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression

artículo científico publicado en 2006

Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.

artículo científico publicado en 2014

Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias

scientific journal article

Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor

artículo científico publicado en 2012

Structure of a mammalian ryanodine receptor

artículo científico publicado en 2014

The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model

artículo científico publicado en 2002

Lista de obras de

A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors

A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.

Acute RyR1 Ca<sup>2+</sup> leak enhances NADH-linked mitochondrial respiratory capacity

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice

Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

Bradycardic therapy improves left ventricular function and remodeling in dogs with coronary embolization-induced chronic heart failure

Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

Intracellular calcium leak as a therapeutic target for RYR1-related myopathies

Late Ventilator-Induced Diaphragmatic Dysfunction After Extubation

Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.

Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties.

Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation

Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure.

Nonshivering thermogenesis protects against defective calcium handling in muscle

Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model

Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization

PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice ⬇️

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits

Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?

Protein kinase A and two phosphatases are components of the inositol 1,4,5-trisphosphate receptor macromolecular signaling complex

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity

Reply from Daniel C. Andersson, Matthew J. Betzenhauser, Steven Reiken, Alisa Umanskaya, Takayuki Shiomi and Andrew R. Marks ⬇️

Reply to Eisner et al.: CaMKII phosphorylation of RyR2 increases cardiac contractility.

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.

Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression

Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.

Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias

Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor

Structure of a mammalian ryanodine receptor

The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model