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Activation of the p53 pathway induces α-smooth muscle actin expression in both myeloid leukemic cells and normal macrophages

artículo científico publicado en 2012

DNA prime and protein boost immunization with innovative polymeric cationic core-shell nanoparticles elicits broad immune responses and strongly enhance cellular responses of HIV-1 tat DNA vaccination

article

Dasatinib plus Nutlin-3 shows synergistic antileukemic activity in both p53 wild-type and p53 mutated B chronic lymphocytic leukemias by inhibiting the Akt pathway

artículo científico publicado en 2010

Endothelial cells obtained from patients affected by chronic venous disease exhibit a pro-inflammatory phenotype

artículo científico publicado en 2012

In vitro endothelial cell proliferation assay reveals distinct levels of proangiogenic cytokines characterizing sera of healthy subjects and of patients with heart failure

artículo científico

Induction of humoral and enhanced cellular immune responses by novel core-shell nanosphere- and microsphere-based vaccine formulations following systemic and mucosal administration

artículo científico publicado en 2009

Intranasal administration of recombinant TRAIL down-regulates CXCL-1/KC in an ovalbumin-induced airway inflammation murine model

artículo científico publicado en 2014

MCL1 down-regulation plays a critical role in mediating the higher anti-leukaemic activity of the multi-kinase inhibitor Sorafenib with respect to Dasatinib.

artículo científico publicado en 2012

Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging

scholarly article in RSC Advances, vol. 4 no. 35, 2014

Nanoparticles engineered with rituximab and loaded with Nutlin-3 show promising therapeutic activity in B-leukemic xenografts

artículo científico publicado en 2013

Nutlin-3 downregulates the expression of the oncogene TCL1 in primary B chronic lymphocytic leukemic cells

artículo científico publicado en 2011

Perifosine plus nutlin-3 combination shows a synergistic anti-leukaemic activity

artículo científico publicado en 2009

Perifosine selectively induces cell cycle block and modulates retinoblastoma and E2F1 protein levels in p53 mutated leukemic cell lines.

artículo científico publicado en 2010

Preparation and Characterization of Innovative Protein-coated Poly(Methylmethacrylate) Core-shell Nanoparticles for Vaccine Purposes

artículo científico publicado en 2007

Priming with a very low dose of DNA complexed with cationic block copolymers followed by protein boost elicits broad and long-lasting antigen-specific humoral and cellular responses in mice

artículo científico publicado en 2009

Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis

artículo científico publicado en 2013

Selective induction of TP53I3/p53-inducible gene 3 (PIG3) in myeloid leukemic cells, but not in normal cells, by Nutlin-3.

artículo científico publicado en 2012

The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells

artículo científico publicado en 2010

The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status

artículo científico publicado en 2012

miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells

artículo científico publicado en 2011