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Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells

artículo científico publicado en 2007

Activation of the p53 pathway induces α-smooth muscle actin expression in both myeloid leukemic cells and normal macrophages

artículo científico publicado en 2012

C-Reactive protein downregulates TRAIL expression in human peripheral monocytes via an Egr-1-dependent pathway

artículo científico publicado en 2013

Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70

article

Endothelial cells obtained from patients affected by chronic venous disease exhibit a pro-inflammatory phenotype

artículo científico publicado en 2012

Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL).

artículo científico publicado en 2006

Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells

artículo científico publicado en 2011

Nutlin-3 downregulates the expression of the oncogene TCL1 in primary B chronic lymphocytic leukemic cells

artículo científico publicado en 2011

Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism

artículo científico publicado en 2009

Reduced expression of cell cycle-associated genes in B lymphocytes purified from the peripheral blood of early-stage B chronic lymphocytic leukaemia patients

artículo científico publicado en 2009

Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells

artículo científico publicado en 2006

Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells

artículo científico publicado en 2007

TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release

artículo científico publicado en 2005

The MDM2 inhibitor Nutlins as an innovative therapeutic tool for the treatment of haematological malignancies

artículo científico publicado en 2008

The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells

artículo científico publicado en 2010

The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status

artículo científico publicado en 2012

Trail down-regulates the release of osteoprotegerin (OPG) by primary stromal cells

artículo científico publicado en 2011

Treatment with recombinant tumor necrosis factor-related apoptosis-inducing ligand alleviates the severity of streptozotocin-induced diabetes

artículo científico publicado en 2010

Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells.

artículo científico publicado en 2008

miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells

artículo científico publicado en 2011