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A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma

artículo científico publicado en 2016

Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization

artículo científico publicado en 2013

Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes

scholarly article

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

artículo científico publicado en 2015

Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis

artículo científico publicado en 2016

Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD.

artículo científico publicado en 2015

Allogeneic stem-cell transplantation in patients with NPM1-mutated acute myeloid leukemia: results from a prospective donor versus no-donor analysis of patients after upfront HLA typing within the SAL-AML 2003 trial

artículo científico publicado en 2014

An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse

artículo científico publicado en 2022

BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: prognostic implications

artículo científico publicado en 2006

BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study

artículo científico publicado en 2003

BCR-ABL Mutation-Guided Therapy for CML Blast Crisis: A Case Report

artículo científico publicado en 2015

Clinical outcome of de novo acute myeloid leukaemia patients with normal cytogenetics is affected by molecular genetic alterations: a concise review

artículo científico publicado en 2007

Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia

artículo científico publicado en 2016

Comparison of minimal residual disease levels in bone marrow and peripheral blood in adult acute lymphoblastic leukemia

artículo científico publicado en 2019

Deep sequencing in CD34+ cells from peripheral blood enables sensitive detection of measurable residual disease in AML

artículo científico publicado en 2022

Does time from diagnosis to treatment affect the prognosis of patients with newly diagnosed acute myeloid leukemia?

artículo científico publicado en 2020

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

artículo científico publicado en 2015

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells

artículo científico

ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling

artículo científico publicado en 2013

EZH2 mutations and impact on clinical outcome - an analysis in 1604 patients with newly diagnosed acute myeloid leukemia

scientific article published on 14 August 2019

Early Thymic Progenitor Leukemia (ETP-ALL) in Adults: A Distinct Molecular Entity, ⬇️

artículo científico publicado en 2011

Epigenetic control of differential expression of specific ERG isoforms in acute T-lymphoblastic leukemia.

artículo científico publicado en 2008

Epigenetic regulation of PAX5 expression in acute T-cell lymphoblastic leukemia

scientific article published on 14 December 2010

Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: An exome sequencing study of 50 patients

artículo científico publicado en 2018

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse ⬇️

artículo científico publicado en 2016

Exome Sequencing Identifies Recurring DNMT3A Mutations in Adult ETP-ALL ⬇️

artículo científico publicado en 2012

Expression of IGFBP7 in acute leukemia is regulated by DNA methylation

artículo científico publicado en 2010

FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications

artículo científico publicado en 2008

FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors

artículo científico publicado en 2013

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

artículo científico publicado en 2016

GATA3 Silencing Defines a Distinct Subset of ETP-ALL. ⬇️

artículo científico publicado en 2012

Gene expression with prognostic implications in cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2008

Genetic Evolution of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) during Therapy and Relapse: An Exome Sequencing Study of 47 Cases ⬇️

scholarly article

Genome-wide DNA-mapping of CD34+ cells from patients with myelodysplastic syndrome using 500K SNP arrays identifies significant regions of deletion and uniparental disomy

artículo científico publicado en 2009

Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL ⬇️

artículo científico publicado en 2015

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CAL

artículo científico publicado en 2008

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

artículo científico publicado en 2010

High Expression Levels of theETS-Related Gene,ERG, Predict Adverse Outcome and Improve Molecular Risk-Based Classification of Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

article

High Rate of FLT3 Mutations In Adult ETP-ALL. ⬇️

scholarly article

High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia ⬇️

artículo científico publicado el 6 de septiembre de 2011

High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults

artículo científico publicado en 2006

High-dose cytarabine consolidation with or without additional amsacrine and mitoxantrone in acute myeloid leukemia: results of the prospective randomized AML2003 trial

artículo científico publicado en 2013

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

artículo científico publicado en 2006

Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL.

artículo científico publicado en 2015

Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures

artículo científico publicado en 2019

Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

scholarly article by Alva Rani James et al published 14 January 2019 in Journal of Hematology & Oncology

Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study

artículo científico publicado en 2007

Low ERG and BAALC expression identifies a new subgroup of adult acute T-lymphoblastic leukemia with a highly favorable outcome

artículo científico publicado en 2007

Low Expression Of BCL11B Predicts Poor Overall Survival In Adult Standard Risk T-ALL ⬇️

scholarly article

Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients

artículo científico publicado en 2014

Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial

artículo científico publicado en 2018

MicroRNA Profiling Reveals Aberrant MicroRNA Expression in Adult ETP-ALL and Functional Studies Demonstrate a Role of Mir-222 in Acute Leukemia, ⬇️

artículo científico publicado en 2011

MicroRNA expression in cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2008

MicroRNA profiling reveals aberrant microRNA expression in adult ETP-ALL and functional studies implicate a role for miR-222 in acute leukemia ⬇️

artículo científico publicado el 20 de marzo de 2013

Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients ⬇️

artículo científico publicado en 2014

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control ⬇️

artículo científico publicado en 2015

Molecular Characterization of Acute Undifferentiated and Biphenotypic Leukemia ⬇️

artículo científico publicado en 2010

Multi-Genomics of Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Reveals Three Distinct Genetic Clusters Characterized By Different Alterations ⬇️

scholarly article

Mutation analysis of hCDC4 in AML cells identifies a new intronic polymorphism

artículo científico publicado en 2006

Mutational landscape of adult ETP-ALL.

artículo científico publicado en 2013

Mutational spectrum of adult T-ALL

artículo científico publicado en 2015

Outlook on PI3K/AKT/mTOR inhibition in acute leukemia

artículo científico

Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia

artículo científico publicado en 2011

Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study

artículo científico publicado en 2005

PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

artículo científico publicado en 2019

Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

artículo científico publicado en 2009

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

artículo científico publicado en 2010

Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

artículo científico publicado en 2009

Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

artículo científico publicado en 2010

Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study

artículo científico publicado en 2008

Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia

artículo científico publicado en 2015

R-split-CHOP chemotherapy for elderly patients with diffuse large B-cell lymphoma

artículo científico publicado en 2014

TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation

artículo científico publicado en 2016

The role of microRNA-196a and microRNA-196b as ERG regulators in acute myeloid leukemia and acute T-lymphoblastic leukemia

artículo científico publicado en 2010

Therapeutic spectrum in the treatment of myelodysplastic syndromes.

artículo científico publicado en 2004

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

artículo científico publicado en 2013

Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

artículo científico publicado en 2008

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