Lista de obras -

A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.

artículo científico publicado en 2010

A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells

artículo científico publicado en 2011

Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors

artículo científico publicado en 2014

Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells

artículo científico publicado en 2011

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated Pathway ⬇️

artículo científico publicado el 6 de septiembre de 2011

Cancerous stem cells can arise from pediatric brain tumors

artículo científico publicado en 2003

Cell lineage and regional identity of cultured spinal cord neural stem cells and comparison to brain-derived neural stem cells

artículo científico publicado en 2009

Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation

artículo científico publicado en 2010

D-2-Hydroxyglutarate Is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-Induced MIR148A Promoter Methylation.

artículo científico publicado en 2018

De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients ⬇️

artículo científico publicado el 26 de marzo de 2013

Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma

artículo científico publicado en 2020

Detection of a microRNA signal in an in vivo expression set of mRNAs

artículo científico publicado en 2007

Directed differentiation of human-induced pluripotent stem cells generates active motor neurons

artículo científico publicado en 2009

Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.

artículo científico publicado en 2007

Endogenous Wnt signaling maintains neural progenitor cell potency

artículo científico publicado en 2009

Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation

artículo científico publicado en 2014

Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS.

artículo científico publicado en 2009

Hydrogel matrix to support stem cell survival after brain transplantation in stroke.

artículo científico publicado en 2010

Identification of an Efficient Gene Expression Panel for Glioblastoma Classification.

artículo científico publicado en 2016

Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors

artículo científico publicado en 2010

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

artículo científico publicado en 2012

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

artículo científico publicado en 2009

Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma

artículo científico publicado en 2016

Introduction to neural stem cells

artículo científico publicado en 2007

Large-scale assessment of the gliomasphere model system

artículo científico publicado en 2016

MELK-a conserved kinase: functions, signaling, cancer, and controversy

artículo científico publicado en 2015

MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.

artículo científico publicado en 2013

Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation

scientific journal article

Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers

artículo científico publicado en 2014

Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells

artículo científico publicado en 2014

MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states

artículo científico publicado en 2010

Molecular markers in glioma

artículo científico publicado en 2017

Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition

artículo científico publicado en 2014

Neural Stem Cells (NSCs) and Proteomics

artículo científico publicado en 2015

Neurosphere formation is an independent predictor of clinical outcome in malignant glioma

artículo científico publicado en 2009

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

artículo científico publicado en 2011

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

artículo científico publicado en 2005

Patterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells

scientific journal article

Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

artículo científico publicado en 2011

Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

scientific article published on February 2009

SPINT2 is hypermethylated in both IDH1 mutated and wild-type glioblastomas, and exerts tumor suppression via reduction of c-Met activation

scientific article published on 05 March 2019

Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway ⬇️

artículo científico publicado el 9 de mayo de 2011

Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury

artículo científico publicado en 2008

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

artículo científico publicado en 2013

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.

artículo científico publicado en 2017

The RAS effector RIN1 modulates the formation of aversive memories

artículo científico publicado en 2003

Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone.

artículo científico publicado en 2014

Lista de obras de

A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.

A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells

Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors

Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated Pathway ⬇️

Cancerous stem cells can arise from pediatric brain tumors

Cell lineage and regional identity of cultured spinal cord neural stem cells and comparison to brain-derived neural stem cells

Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation

D-2-Hydroxyglutarate Is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-Induced MIR148A Promoter Methylation.

De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients ⬇️

Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma

Detection of a microRNA signal in an in vivo expression set of mRNAs

Directed differentiation of human-induced pluripotent stem cells generates active motor neurons

Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.

Endogenous Wnt signaling maintains neural progenitor cell potency

Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation

Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS.

Hydrogel matrix to support stem cell survival after brain transplantation in stroke.

Identification of an Efficient Gene Expression Panel for Glioblastoma Classification.

Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma

Introduction to neural stem cells

Large-scale assessment of the gliomasphere model system

MELK-a conserved kinase: functions, signaling, cancer, and controversy

MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.

Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation

Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers

Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells

MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states

Molecular markers in glioma

Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition

Neural Stem Cells (NSCs) and Proteomics

Neurosphere formation is an independent predictor of clinical outcome in malignant glioma

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

Patterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells

Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

SPINT2 is hypermethylated in both IDH1 mutated and wild-type glioblastomas, and exerts tumor suppression via reduction of c-Met activation

Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway ⬇️

Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.

The RAS effector RIN1 modulates the formation of aversive memories

Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone.