Lista de obras -

"Pure by NMR"?

artículo científico publicado en 2008

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.

artículo científico publicado en 2017

A blood-based metabolomics test to distinguish relapsing-remitting and secondary progressive multiple sclerosis: addressing practical considerations for clinical application

scientific article published on 24 July 2020

A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms.

artículo científico publicado en 2017

A two-directional approach to enantiopure 1,4-difluoro-cyclohexenes: synthesis of difluorinated cyclitol analogues

scientific article published on 03 September 2008

A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis

artículo científico publicado en 2014

AC-linked Glycomimetic in the Gas Phase and in Solution: Synthesis and Conformation of the Disaccharide Manα(1,6)-C-ManαOPh

artículo científico publicado en 2009

All-or-nothing cooperative self-assembly of an annulene sandwich

artículo científico publicado en 2011

Ammonium-directed dihydroxylation of 3-aminocyclohex-1-enes: development of a metal-free dihydroxylation protocol

artículo científico publicado en 2008

Ammonium-directed olefinic epoxidation: kinetic and mechanistic insights

scientific article published on 13 August 2012

Amylose-wrapped luminescent conjugated polymers

artículo científico publicado en 2008

An unsaturated peptidomimetic assembly derived from a carbohydrate

artículo científico publicado en 2004

Anatomy of a simple acyl intermediate in enzyme catalysis: combined biophysical and modeling studies on ornithine acetyl transferase

artículo científico publicado en 2009

Anomalous nuclear Overhauser effects in carbon-substituted aziridines: scalar cross-relaxation of the first kind

artículo científico publicado en 2015

Aromatic and antiaromatic ring currents in a molecular nanoring

artículo científico publicado en 2016

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor

artículo científico publicado en 2011

Barrierless Photoisomerization of 11-cis Retinal Protonated Schiff Base in Solution

scientific article published on 24 September 2015

Bend ribbon-forming tetrahydrofuran amino acids

artículo científico publicado en 2003

Binding of (5S)-penicilloic acid to penicillin binding protein 3

artículo científico publicado en 2013

Biomimetic synthesis of the crispatene core

artículo científico publicado en 2003

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

artículo científico publicado en 2010

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

artículo científico publicado en 2015

Cephalosporins inhibit human metallo β-lactamase fold DNA repair nucleases SNM1A and SNM1B/apollo.

artículo científico publicado en 2016

Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients

artículo científico publicado en 2015

ChemInform Abstract: Fluoromethylated Derivatives of Carnitine biosynthesis Intermediates - Synthesis and Applications

Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling

artículo científico publicado en 2019

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase

article

Conformational studies of oligomeric oxetane-based dipeptide isosteres derived from L-rhamnose or D-xylose.

artículo científico publicado en 2005

Cover Picture: Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy (Angew. Chem. Int. Ed. 12/2014)

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

article

Development and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylase

artículo científico publicado en 2012

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

artículo científico publicado en 2012

Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice

artículo científico publicado en 2016

Endohexosaminidase M: Exploring and Exploiting Enzyme Substrate Specificity

artículo científico publicado en 2006

Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

artículo científico publicado en 2009

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

artículo científico publicado en 2011

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

artículo científico publicado en 2014

From Disulfide- to Thioether-Linked Glycoproteins

artículo científico publicado en 2008

Frontispiece: Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Global Aromaticity and Antiaromaticity in Porphyrin Nanoring Anions

Global Aromaticity at the Nanoscale

Group epitope mapping considering relaxation of the ligand (GEM-CRL): including longitudinal relaxation rates in the analysis of saturation transfer difference (STD) experiments

artículo científico publicado en 2009

Harnessing NMR relaxation interference effects to characterise supramolecular assemblies

artículo científico publicado en 2016

Helix-forming carbohydrate amino acids

artículo científico publicado en 2005

Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide

artículo científico publicado en 2008

Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation

artículo científico publicado en 2014

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate

artículo científico publicado en 2005

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris

artículo científico publicado en 2007

Integrative biochemical, proteomics and metabolomics cerebrospinal fluid biomarkers predict clinical conversion to multiple sclerosis

artículo científico publicado en 2021

Interaction of Avibactam with Class B Metallo-β-Lactamases

artículo científico publicado en 2016

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen

artículo científico publicado en 2014

Investigations into the Manzamine Alkaloid Biosynthetic Hypothesis.

artículo científico publicado en 1998

Is JmjC oxygenase catalysis limited to demethylation?

artículo científico publicado en 2013

Mechanistic Investigation of Rh(I)-Catalyzed Asymmetric Suzuki-Miyaura Coupling with Racemic Allyl Halides

Metal-driven ligand assembly in the synthesis of cyclodextrin [2] and [3]rotaxanes

artículo científico publicado en 2007

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

artículo científico publicado en 2017

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy

Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy

artículo científico publicado en 2014

Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde

artículo científico publicado en 2010

NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis.

artículo científico publicado en 2015

Nitrogen inversion as a diastereomeric relay in azasugar synthesis: the first synthesis of adenophorine

scientific article published on 01 August 2003

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

artículo científico publicado en 2014

Normal tissue radioprotection by amifostine via Warburg-type effects

artículo científico publicado en 2016

Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids

artículo científico publicado en 2014

Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

artículo científico publicado en 2012

Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis

artículo científico publicado en 2018

Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

artículo científico publicado en 2020

Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.

artículo científico publicado en 2016

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

artículo científico publicado en 2015

Protein-ligand binding affinity determination by the waterLOGSY method: An optimised approach considering ligand rebinding.

artículo científico publicado en 2017

Reducing agent mediated non-enzymatic conversion of 2-oxoglutarate to succinate - implications for oxygenase assays

artículo científico publicado en 2020

Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors

artículo científico publicado en 2013

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

artículo científico publicado en 2014

Saturation transfer difference NMR reveals functionally essential kinetic differences for a sugar-binding repressor protein

artículo científico publicado en 2009

Scalar Cross-Relaxation Detected in the NOESY Spectra of Oxazolidines and Thiazolidines.

artículo científico publicado en 2016

Sequential desymmetrization-fluorination: enantioselective synthesis of fluorinated cyclitols

artículo científico publicado en 2006

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases

artículo científico publicado en 2011

Stereoselective Production of Dimethyl-Substituted Carbapenams via Engineered Carbapenem Biosynthesis Enzymes

Stereoselective preparation of lipidated carboxymethyl-proline/pipecolic acid derivatives via coupling of engineered crotonases with an alkylmalonyl-CoA synthetase

artículo científico publicado en 2013

Stereospecific anti SE2' fluorination of allenylsilanes: synthesis of enantioenriched propargylic fluorides

scientific article published on 03 April 2008

Structural and mechanistic studies on γ-butyrobetaine hydroxylase

artículo científico publicado en 2010

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.

artículo científico publicado en 2016

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

artículo científico publicado en 2002

Structure and reactivity of bicyclic methylene aziridines prepared by intramolecular aziridination of allenes

artículo científico publicado en 2010

Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases.

artículo científico publicado en 2014

Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans

artículo científico publicado en 2015

Studies on the reaction of glutathione and formaldehyde using NMR.

artículo científico publicado en 2010

Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles

scientific article published on 28 October 2019

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1†Electronic supplementary information (ESI) available: Procedures for protein expression and purification, 19F-labelling, crystallisation, data collection, and structure de

artículo científico publicado en 2014

Substrate selectivity analyses of factor inhibiting hypoxia-inducible factor

artículo científico publicado en 2013

Swarm formation in the desert locust Schistocerca gregaria: isolation and NMR analysis of the primary maternal gregarizing agent

artículo científico publicado en 2008

Synthesis and characterization of a novel N-F reagent derived from the ethano-Tröger's base: (1)J(FN) coupling constants as a signature for the N-F bond

artículo científico publicado en 2015

Synthesis and conformational analysis of cyclic analogues of inverse γ-turns

article

Synthesis of N-glycan oxazolines: donors for endohexosaminidase catalysed glycosylation

artículo científico publicado en 2006

Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹⁹F NMR studies.

artículo científico publicado en 2015

Synthesis, structure and dynamics of methoxynaphthalene-substituted phospha-ruthenocenes and -ferrocenes

artículo científico publicado en 2005

Synthetic Control of Retinal Photochemistry and Photophysics in Solution

artículo científico publicado en 2014

Terminalia bentzoë, a Mascarene Endemic Plant, Inhibits Human Hepatocellular Carcinoma Cells Growth In Vitro via G0/G1 Phase Cell Cycle Arrest

scientific article published on 12 October 2020

Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases

artículo científico publicado en 2017

The 2-Oxoglutarate-Dependent Oxygenase JMJD6 Catalyses Oxidation of Lysine Residues to give 5S-Hydroxylysine Residues

artículo científico publicado en 2011

The broad spectrum 2-oxoglutarate oxygenase inhibitor N-oxalylglycine is present in rhubarb and spinach leaves.

artículo científico publicado en 2015

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

artículo científico publicado en 2011

The synthesis of oligomers of oxetane-based dipeptide isosteres derived from L-rhamnose or D-xylose

artículo científico publicado en 2005

Thioester Hydrolysis and CC Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily

artículo científico publicado en 2008

Titelbild: Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy (Angew. Chem. 12/2014)

Torsional and Electronic Factors Control the C-H⋅⋅⋅O Interaction

artículo científico publicado en 2016

Tuning the Cavity of Cyclodextrins: Altered Sugar Adaptors in Protein Pores

article by Wen-Wu Li et al published 16 February 2011 in Journal of the American Chemical Society

Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions

artículo científico publicado en 2010

Vernier templating and synthesis of a 12-porphyrin nano-ring

artículo científico publicado en 2011

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation

artículo científico publicado en 2017

α- and α'-Lithiation-Electrophile Trapping of N-Thiopivaloyl and N-tert-Butoxythiocarbonyl α-Substituted Azetidines: Rationalization of the Regiodivergence Using NMR and Computation

artículo científico publicado en 2015

γ-Butyrobetaine hydroxylase catalyses a Stevens type rearrangement

artículo científico publicado en 2012

Lista de obras de

"Pure by NMR"?

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.

A blood-based metabolomics test to distinguish relapsing-remitting and secondary progressive multiple sclerosis: addressing practical considerations for clinical application

A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms.

A two-directional approach to enantiopure 1,4-difluoro-cyclohexenes: synthesis of difluorinated cyclitol analogues

A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis

AC-linked Glycomimetic in the Gas Phase and in Solution: Synthesis and Conformation of the Disaccharide Manα(1,6)-C-ManαOPh

All-or-nothing cooperative self-assembly of an annulene sandwich

Ammonium-directed dihydroxylation of 3-aminocyclohex-1-enes: development of a metal-free dihydroxylation protocol

Ammonium-directed olefinic epoxidation: kinetic and mechanistic insights

Amylose-wrapped luminescent conjugated polymers

An unsaturated peptidomimetic assembly derived from a carbohydrate

Anatomy of a simple acyl intermediate in enzyme catalysis: combined biophysical and modeling studies on ornithine acetyl transferase

Anomalous nuclear Overhauser effects in carbon-substituted aziridines: scalar cross-relaxation of the first kind

Aromatic and antiaromatic ring currents in a molecular nanoring

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor

Barrierless Photoisomerization of 11-cis Retinal Protonated Schiff Base in Solution

Bend ribbon-forming tetrahydrofuran amino acids

Binding of (5S)-penicilloic acid to penicillin binding protein 3

Biomimetic synthesis of the crispatene core

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Cephalosporins inhibit human metallo β-lactamase fold DNA repair nucleases SNM1A and SNM1B/apollo.

Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients

ChemInform Abstract: Fluoromethylated Derivatives of Carnitine biosynthesis Intermediates - Synthesis and Applications

Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase

Conformational studies of oligomeric oxetane-based dipeptide isosteres derived from L-rhamnose or D-xylose.

Cover Picture: Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy (Angew. Chem. Int. Ed. 12/2014)

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

Development and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylase

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice

Endohexosaminidase M: Exploring and Exploiting Enzyme Substrate Specificity

Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

From Disulfide- to Thioether-Linked Glycoproteins

Frontispiece: Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Global Aromaticity and Antiaromaticity in Porphyrin Nanoring Anions

Global Aromaticity at the Nanoscale

Group epitope mapping considering relaxation of the ligand (GEM-CRL): including longitudinal relaxation rates in the analysis of saturation transfer difference (STD) experiments

Harnessing NMR relaxation interference effects to characterise supramolecular assemblies

Helix-forming carbohydrate amino acids

Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide

Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris

Integrative biochemical, proteomics and metabolomics cerebrospinal fluid biomarkers predict clinical conversion to multiple sclerosis

Interaction of Avibactam with Class B Metallo-β-Lactamases

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen

Investigations into the Manzamine Alkaloid Biosynthetic Hypothesis.

Is JmjC oxygenase catalysis limited to demethylation?

Mechanistic Investigation of Rh(I)-Catalyzed Asymmetric Suzuki-Miyaura Coupling with Racemic Allyl Halides

Metal-driven ligand assembly in the synthesis of cyclodextrin [2] and [3]rotaxanes

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy

Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy

Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde

NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis.

Nitrogen inversion as a diastereomeric relay in azasugar synthesis: the first synthesis of adenophorine

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

Normal tissue radioprotection by amifostine via Warburg-type effects

Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids

Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis

Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Protein-ligand binding affinity determination by the waterLOGSY method: An optimised approach considering ligand rebinding.

Reducing agent mediated non-enzymatic conversion of 2-oxoglutarate to succinate - implications for oxygenase assays

Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Saturation transfer difference NMR reveals functionally essential kinetic differences for a sugar-binding repressor protein

Scalar Cross-Relaxation Detected in the NOESY Spectra of Oxazolidines and Thiazolidines.

Sequential desymmetrization-fluorination: enantioselective synthesis of fluorinated cyclitols

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases