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5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases

artículo científico publicado en 2007

5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors.

artículo científico publicado en 2009

A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase

artículo científico publicado en 2003

A proteomic approach to the investigation of early events involved in the activation of vascular smooth muscle cells.

artículo científico publicado en 2007

A proteomic approach to the investigation of early events involved in vascular smooth muscle cell activation.

artículo científico publicado en 2007

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches

artículo científico publicado en 2011

Effect of natural compounds on insulin signaling

artículo científico publicado en 2015

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives

artículo científico publicado en 2016

Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation

artículo científico publicado en 2002

Kinetic mechanism of the Zn-dependent aryl-phosphatase activity of myo-inositol-1-phosphatase

artículo científico publicado en 2006

Low molecular weight protein tyrosine phosphatase and caveolin-1: interaction and isoenzyme-dependent regulation.

artículo científico publicado en 2007

New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells

artículo científico publicado en 2012

New perspectives in PDGF receptor downregulation: the main role of phosphotyrosine phosphatases.

artículo científico publicado en 2002

PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway

artículo científico publicado en 2009

Preparation and properties of des-Tyr98 and des-Arg97-Tyr98 acylphosphatase (muscular isoenzyme)

Proliferation versus migration in platelet-derived growth factor signaling: the key role of endocytosis.

artículo científico publicado en 2008

Protein N-homocysteinylation induces the formation of toxic amyloid-like protofibrils.

artículo científico publicado en 2010

Site-directed mutagenesis of two aromatic residues lining the active site pocket of the yeast Ltp1

artículo científico publicado en 2007

Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.

artículo científico publicado en 2009

Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition

artículo científico publicado en 2014

Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors.

artículo científico publicado en 2009

Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity.

artículo científico publicado en 2009

Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors

artículo científico publicado en 2012

The effects of CA IX catalysis products within tumor microenvironment.

artículo científico publicado en 2013

The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1.

artículo científico publicado en 2004

The insulin-mimetic effect of Morin: a promising molecule in diabetes treatment

artículo científico publicado en 2013

Thiolation of Low-Mr Phosphotyrosine Protein Phosphatase by Thiol-Disulfides

Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.

artículo científico publicado en 2018