Lista de obras -

6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein

artículo científico publicado en 2012

A Synthetic Chalcone as a Potent Inducer of Glutathione Biosynthesis ⬇️

artículo científico publicado el 30 de enero de 2012

A new P-glycoprotein inhibitor from the caper spurge (Euphorbia lathyris).

artículo científico publicado en 2003

A template model for studying anticancer drug efflux transporter inhibitors in vitro

artículo científico publicado en 2012

ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity

artículo científico publicado en 2013

ABCG2 transports and transfers heme to albumin through its large extracellular loop

artículo científico publicado en 2010

ABCG2: recent discovery of potent and highly selective inhibitors

artículo científico

Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.

artículo científico publicado en 2007

Anticancer multidrug resistance mediated by MRP1: recent advances in the discovery of reversal agents

artículo científico publicado en 2005

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

artículo científico publicado en 2013

Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells

artículo científico publicado en 2009

Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

artículo científico publicado en 2009

Characterization of YvcC (BmrA), a multidrug ABC transporter constitutively expressed in Bacillus subtilis

artículo científico publicado en 2004

ChemInform Abstract: The Flavanolignan Silybin and Its Hemisynthetic Derivatives, a Novel Series of Potential Modulators of P-Glycoprotein

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux

artículo científico publicado en 2014

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux

artículo científico publicado en 2006

Dexamethasone down-regulates ABCG2 expression levels in breast cancer cells.

artículo científico publicado en 2008

Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells

artículo científico publicado en 2011

Ferrocene-embedded flavonoids targeting the Achilles heel of multidrug-resistant cancer cells through collateral sensitivity

artículo científico publicado en 2017

Highly efficient over-production in E. coli of YvcC, a multidrug-like ATP-binding cassette transporter from Bacillus subtilis.

artículo científico publicado en 2002

Identification of specific reversal agents for Leishmania ABCI4-mediated antimony resistance by flavonoid and trolox derivative screening

artículo científico publicado en 2013

Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1.

artículo científico publicado en 2011

Inhibitors of cancer cell multidrug resistance mediated by breast cancer resistance protein (BCRP/ABCG2).

artículo científico publicado en 2006

Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity

artículo científico publicado en 2012

Jatrophanes from Euphorbia squamosa as Potent Inhibitors of Candida albicans Multidrug Transporters

artículo científico publicado en 2014

Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models

artículo científico publicado en 2013

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

artículo científico publicado en 2014

MRP1-dependent Collateral Sensitivity of Multidrug-resistant Cancer Cells: Identifying Selective Modulators Inducing Cellular Glutathione Depletion.

artículo científico publicado en 2016

MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors ⬇️

artículo científico publicado el 20 de enero de 2011

Make azoles active again: chalcones as potent reversal agents of transporters-mediated resistance in Candida albicans

scientific article published on 25 July 2018

Methoxy stilbenes as potent, specific, untransported, and noncytotoxic inhibitors of breast cancer resistance protein

artículo científico publicado en 2011

Microparticle-mediated transfer of the viral receptors CAR and CD46, and the CFTR channel in a CHO cell model confers new functions to target cells

artículo científico publicado en 2012

Multidrug resistance ABC transporter structure predictions by homology modeling approaches

artículo científico publicado en 2011

New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity

artículo científico publicado en 2013

New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2.

artículo científico publicado en 2016

Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors

artículo científico publicado en 2007

Pharmacokinetic interactions in mice between irinotecan and MBL-II-141, an ABCG2 inhibitor.

artículo científico publicado en 2017

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

artículo científico publicado en 2012

Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity

artículo científico publicado en 2015

Potent and fully noncompetitive peptidomimetic inhibitor of multidrug resistance P-glycoprotein.

artículo científico publicado en 2010

Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953

artículo científico publicado en 2003

Probing the conformation of the resting state of a bacterial multidrug ABC transporter, BmrA, by a site-directed spin labeling approach

artículo científico publicado en 2009

Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model.

artículo científico publicado en 2013

Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position

artículo científico publicado en 2014

Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.

artículo científico publicado en 2002

Recent trends of chalcones potentialities as antiproliferative and antiresistance agents

artículo científico publicado en 2015

Selective Cytotoxicity of 1,3,4-Thiadiazolium Mesoionic Derivatives on Hepatocarcinoma Cells (HepG2)

artículo científico publicado en 2015

Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2.

artículo científico publicado en 2013

Structuring detergents for extracting and stabilizing functional membrane proteins

artículo científico publicado en 2011

Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein

artículo científico publicado en 2012

Symmetric bis-chalcones as a new type of breast cancer resistance protein inhibitors with a mechanism different from that of chromones

artículo científico publicado en 2014

Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance

artículo científico publicado en 2014

Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2

artículo científico publicado en 2020

Understanding polyspecificity within the substrate-binding cavity of the human multidrug resistance P-glycoprotein

artículo científico publicado en 2014

Lista de obras de

6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein

A Synthetic Chalcone as a Potent Inducer of Glutathione Biosynthesis ⬇️

A new P-glycoprotein inhibitor from the caper spurge (Euphorbia lathyris).

A template model for studying anticancer drug efflux transporter inhibitors in vitro

ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity

ABCG2 transports and transfers heme to albumin through its large extracellular loop

ABCG2: recent discovery of potent and highly selective inhibitors

Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.

Anticancer multidrug resistance mediated by MRP1: recent advances in the discovery of reversal agents

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells

Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

Characterization of YvcC (BmrA), a multidrug ABC transporter constitutively expressed in Bacillus subtilis

ChemInform Abstract: The Flavanolignan Silybin and Its Hemisynthetic Derivatives, a Novel Series of Potential Modulators of P-Glycoprotein

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux

Dexamethasone down-regulates ABCG2 expression levels in breast cancer cells.

Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells

Ferrocene-embedded flavonoids targeting the Achilles heel of multidrug-resistant cancer cells through collateral sensitivity

Highly efficient over-production in E. coli of YvcC, a multidrug-like ATP-binding cassette transporter from Bacillus subtilis.

Identification of specific reversal agents for Leishmania ABCI4-mediated antimony resistance by flavonoid and trolox derivative screening

Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1.

Inhibitors of cancer cell multidrug resistance mediated by breast cancer resistance protein (BCRP/ABCG2).

Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity

Jatrophanes from Euphorbia squamosa as Potent Inhibitors of Candida albicans Multidrug Transporters

Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

MRP1-dependent Collateral Sensitivity of Multidrug-resistant Cancer Cells: Identifying Selective Modulators Inducing Cellular Glutathione Depletion.

MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors ⬇️

Make azoles active again: chalcones as potent reversal agents of transporters-mediated resistance in Candida albicans

Methoxy stilbenes as potent, specific, untransported, and noncytotoxic inhibitors of breast cancer resistance protein

Microparticle-mediated transfer of the viral receptors CAR and CD46, and the CFTR channel in a CHO cell model confers new functions to target cells

Multidrug resistance ABC transporter structure predictions by homology modeling approaches

New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity

New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2.

Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors

Pharmacokinetic interactions in mice between irinotecan and MBL-II-141, an ABCG2 inhibitor.

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity

Potent and fully noncompetitive peptidomimetic inhibitor of multidrug resistance P-glycoprotein.

Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953

Probing the conformation of the resting state of a bacterial multidrug ABC transporter, BmrA, by a site-directed spin labeling approach

Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model.

Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position

Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.

Recent trends of chalcones potentialities as antiproliferative and antiresistance agents

Selective Cytotoxicity of 1,3,4-Thiadiazolium Mesoionic Derivatives on Hepatocarcinoma Cells (HepG2)

Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2.

Structuring detergents for extracting and stabilizing functional membrane proteins

Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein

Symmetric bis-chalcones as a new type of breast cancer resistance protein inhibitors with a mechanism different from that of chromones

Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance

Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2

Understanding polyspecificity within the substrate-binding cavity of the human multidrug resistance P-glycoprotein