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CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

artículo científico publicado en 2004

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians

artículo científico publicado en 2004

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.

artículo científico publicado en 2006

Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

artículo científico publicado en 2003

Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection

artículo científico publicado en 2007

Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy.

artículo científico publicado en 2008

HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition

artículo científico publicado en 2008

Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals

artículo científico publicado en 2010

Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa

artículo científico publicado en 2006

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

artículo científico publicado en 2010

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

artículo científico publicado en 2005

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

artículo científico publicado en 2007