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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

artículo científico publicado en 2013

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

artículo científico publicado en 2015

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

artículo científico publicado en 2016

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

artículo científico publicado en 2017

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

artículo científico publicado en 2017

Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers

artículo científico publicado en 2020

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

artículo científico publicado en 2019

Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers

artículo científico publicado en 2017

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

artículo científico publicado en 2014

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

scientific article published on 29 May 2019