Lista de obras -

2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.

artículo científico publicado en 2005

Allosteric Modulation of Chemoattractant Receptors

artículo científico publicado en 2016

Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls

artículo científico publicado en 2008

Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.

artículo científico publicado en 2018

Antitumor effects of a human dimeric antibody fragment 131I-AFRA-DFM5.3 in a mouse model for ovarian cancer

artículo científico publicado en 2011

Aryltriflates as a Neglected Moiety in Medicinal Chemistry: A Case Study from a Lead Optimization of CXCL8 Inhibitors

artículo científico publicado en 2011

Autocrine CXCL8-dependent invasiveness triggers modulation of actin cytoskeletal network and cell dynamics

scientific article published on 27 January 2020

Binding Mode Exploration of B1 Receptor Antagonists' by the Use of Molecular Dynamics and Docking Simulation-How Different Target Engagement Can Determine Different Biological Effects

artículo científico publicado en 2020

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

artículo científico publicado en 2020

CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice

artículo científico publicado en 2020

CXCR1/2 Antagonism Is Protective during Influenza and Post-Influenza Pneumococcal Infection.

artículo científico publicado en 2017

CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice

artículo científico publicado en 2014

CXCR1/2 inhibition enhances pancreatic islet survival after transplantation

artículo científico publicado en 2012

CXCR1/2 pathways in paclitaxel-induced neuropathic pain

artículo científico publicado en 2017

Carbocysteine lysine salt monohydrate (SCMC-LYS) is a selective scavenger of reactive oxygen intermediates (ROIs).

artículo científico publicado en 2003

Chemokine Signaling in Chemotherapy-Induced Neuropathic Pain

scientific article published on 14 June 2019

Conversion of murine antibodies to human antibodies and their optimization for ovarian cancer therapy targeted to the folate receptor.

artículo científico publicado en 2008

Correction to: The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

scientific article published on 01 August 2019

Correction: Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis

artículo científico publicado en 2019

Current status of chemokine receptor inhibitors in development

artículo científico publicado en 2012

DF2726A, a new IL-8 signalling inhibitor, is able to counteract chemotherapy-induced neuropathic pain

artículo científico publicado en 2019

DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain

artículo científico publicado en 2015

DF3016A induces increased BDNF transcription in ischemic neuroinflammation injury

artículo científico publicado en 2020

DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats.

artículo científico publicado en 2015

Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2

artículo científico publicado en 2007

Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.

artículo científico publicado en 2009

Development of a systemically-active dual CXCR1/CXCR2 allosteric inhibitor and its efficacy in a model of transient cerebral ischemia in the rat.

artículo científico publicado en 2006

Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.

artículo científico

ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets

artículo científico publicado en 2006

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study

artículo científico publicado en 2019

Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise

artículo científico publicado en 2020

FOCUS ON THE USE OF RESVERATROL AS ADJUVANT IN GLIOBLASTOMA THERAPHY

scientific article published on 31 March 2020

Gastroprotective Effects of L-Lysine Salification of Ketoprofen in Ethanol-Injured Gastric Mucosa

Intravital Microscopic Evaluation of the Effects of a CXCR2 Antagonist in a Model of Liver Ischemia Reperfusion Injury in Mice

artículo científico publicado en 2017

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells

artículo científico publicado en 2009

Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment

artículo científico publicado en 2017

Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis

artículo científico publicado en 2008

Multiple anti-tumor effects of Reparixin on thyroid cancer

artículo científico publicado en 2017

NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes

artículo científico publicado en 2020

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

scholarly article

Phase I Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis

Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis

Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury.

artículo científico publicado en 2004

Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors

artículo científico publicado en 2009

Synthesis of E-Aryl Ethenesulfonamides: A Simple One-Pot, Two-Step Procedure from 1-Hydroxy-1-arylalkanes ⬇️

artículo científico publicado el 3 de octubre de 2003

Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling

artículo científico publicado en 2015

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

artículo científico publicado en 2014

The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

scientific article published on 05 April 2019

Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial

artículo científico publicado en 2019

Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs).

artículo científico publicado en 2016

Lista de obras de

2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.

Allosteric Modulation of Chemoattractant Receptors

Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls

Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.

Antitumor effects of a human dimeric antibody fragment 131I-AFRA-DFM5.3 in a mouse model for ovarian cancer

Aryltriflates as a Neglected Moiety in Medicinal Chemistry: A Case Study from a Lead Optimization of CXCL8 Inhibitors

Autocrine CXCL8-dependent invasiveness triggers modulation of actin cytoskeletal network and cell dynamics

Binding Mode Exploration of B1 Receptor Antagonists' by the Use of Molecular Dynamics and Docking Simulation-How Different Target Engagement Can Determine Different Biological Effects

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice

CXCR1/2 Antagonism Is Protective during Influenza and Post-Influenza Pneumococcal Infection.

CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice

CXCR1/2 inhibition enhances pancreatic islet survival after transplantation

CXCR1/2 pathways in paclitaxel-induced neuropathic pain

Carbocysteine lysine salt monohydrate (SCMC-LYS) is a selective scavenger of reactive oxygen intermediates (ROIs).

Chemokine Signaling in Chemotherapy-Induced Neuropathic Pain

Conversion of murine antibodies to human antibodies and their optimization for ovarian cancer therapy targeted to the folate receptor.

Correction to: The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

Correction: Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis

Current status of chemokine receptor inhibitors in development

DF2726A, a new IL-8 signalling inhibitor, is able to counteract chemotherapy-induced neuropathic pain

DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain

DF3016A induces increased BDNF transcription in ischemic neuroinflammation injury

DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats.

Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2

Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.

Development of a systemically-active dual CXCR1/CXCR2 allosteric inhibitor and its efficacy in a model of transient cerebral ischemia in the rat.

Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.

ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study

Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise

FOCUS ON THE USE OF RESVERATROL AS ADJUVANT IN GLIOBLASTOMA THERAPHY

Gastroprotective Effects of L-Lysine Salification of Ketoprofen in Ethanol-Injured Gastric Mucosa

Intravital Microscopic Evaluation of the Effects of a CXCR2 Antagonist in a Model of Liver Ischemia Reperfusion Injury in Mice

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells

Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment

Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis

Multiple anti-tumor effects of Reparixin on thyroid cancer

NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

Phase I Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis

Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis

Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury.

Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors

Synthesis of E-Aryl Ethenesulfonamides: A Simple One-Pot, Two-Step Procedure from 1-Hydroxy-1-arylalkanes ⬇️

Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial

Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs).