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1,3-Dibromo-1,1-difluoro-2-propanone as a Useful Synthon for a Chemoselective Preparation of 4-Bromodifluoromethyl Thiazoles

artículo científico publicado en 2018

Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.

artículo científico publicado en 2018

Catalyst-Free Synthesis of Polysubstituted 5-Acylamino-1,3-Thiazoles via Hantzsch Cyclization of α-Chloroglycinates

artículo científico publicado en 2019

DF2726A, a new IL-8 signalling inhibitor, is able to counteract chemotherapy-induced neuropathic pain

artículo científico publicado en 2019

DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain

artículo científico publicado en 2015

DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats

artículo científico publicado en 2015

Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2

artículo científico publicado en 2007

Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.

artículo científico publicado en 2009

Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.

artículo científico

Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise

artículo científico publicado en 2020

Inhibition of osteoclast activity by complement regulation with DF3016A, a novel small-molecular-weight C5aR inhibitor

scientific article published on 31 December 2019

NK1 receptor antagonists as a new treatment for corneal neovascularization.

artículo científico publicado en 2014

Phosphorus trichloride-mediated and microwave-assisted synthesis of a small collection of amides bearing strong electron-withdrawing group substituted anilines

artículo científico publicado en 2009

Straightforward chemo- and stereoselective fluorocyclopropanation of allylic alcohols: exploiting the electrophilic nature of the not so elusive fluoroiodomethyllithium

artículo científico publicado en 2019

Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors

artículo científico publicado en 2009

Synthesis of E-Aryl Ethenesulfonamides: A Simple One-Pot, Two-Step Procedure from 1-Hydroxy-1-arylalkanes

artículo científico publicado el 3 de octubre de 2003

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

artículo científico publicado en 2014

The 15N induced isotope shift as an effective tool for the structure elucidation of 2,4 and 2,5 di-substituted thiazoles