Lista de obras -

A Dynamic Transcriptional Analysis Reveals IL-6 Axis as a Prominent Mediator of Surgical Acute Response in Non-ischemic Mouse Heart

scientific article published on 31 October 2019

Acute myocardial infarction in mice: assessment of transmurality by strain rate imaging

artículo científico publicado en 2007

An optimal experimental design for the development of preservative heart solutions

artículo científico publicado en 2002

Brain death does not change epicardial action potentials and their response to ischemia-reperfusion in open-chest pigs.

artículo científico publicado en 2006

Brain death provokes very acute alteration in myocardial morphology detected by echocardiography: preventive effect of beta-blockers

artículo científico publicado en 2010

Cardiac fibroblasts protect cardiomyocytes against lethal ischemia-reperfusion injury.

artículo científico publicado en 2014

Cardioprotection in the clinical setting

artículo científico publicado en 2010

Cardioprotective effect of VEGF and venom VEGF-like protein in acute myocardial ischemia in mice: effect on mitochondrial function

artículo científico publicado en 2014

Ceramide in the antiapoptotic effect of ischemic preconditioning

artículo científico publicado en 2003

Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials.

artículo científico publicado en 2017

Critical appraisal of STAT3 pattern in adult cardiomyocytes

scientific article published on 22 April 2019

Cyclophilin D and myocardial ischemia-reperfusion injury: a fresh perspective.

artículo científico

Cyclosporine A at reperfusion fails to reduce infarct size in the in vivo rat heart

artículo científico publicado en 2013

Cyclosporine A, a Potential Therapy of Ischemic Reperfusion Injury. A Common History for Heart and Brain

artículo científico publicado en 2016

Cyclosporine before PCI in Patients with Acute Myocardial Infarction

artículo científico publicado en 2015

Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention

artículo científico

Delayed low pressure at reperfusion: A new approach for cardioprotection.

artículo científico publicado en 2015

Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury.

artículo científico publicado en 2013

Desflurane-induced preconditioning alters calcium-induced mitochondrial permeability transition.

artículo científico publicado en 2004

Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening ⬇️

artículo científico publicado el 26 de enero de 2011

Determination of the myocardial area at risk after reperfused acute myocardial infarction with different imaging techniques: cardiac magnetic resonance imaging, multidetector computed tomography and histopathological validation

artículo científico publicado en 2011

Determination of the myocardial area at risk with pre- versus post-reperfusion imaging techniques in the pig model

artículo científico publicado en 2011

Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance.

artículo científico publicado en 2015

Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice.

artículo científico publicado en 2017

ER stress inhibits neuronal death by promoting autophagy

artículo científico publicado en 2012

ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies

artículo científico publicado en 2014

Effect of Cyclosporine in Nonshockable Out-of-Hospital Cardiac Arrest: The CYRUS Randomized Clinical Trial

artículo científico

Effect of Cyclosporine on Lesion Growth and Infarct Size within the White and Gray Matter.

artículo científico publicado en 2017

Efficient and non-toxic gene transfer to cardiomyocytes using novel generation amplicon vectors derived from HSV-1.

artículo científico publicado en 2004

Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition ⬇️

artículo científico publicado el 7 de junio de 2013

Evaluation of cyclosporine A in a stroke model in the immature rat brain

artículo científico publicado en 2010

Evolving therapies for myocardial ischemia/reperfusion injury.

artículo científico

Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition

artículo científico publicado en 2017

Formation of palmitic acid/Ca2+ complexes in the mitochondrial membrane: a possible role in the cyclosporin-insensitive permeability transition

artículo científico publicado en 2004

Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model.

artículo científico publicado en 2016

Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts

artículo científico publicado en 2007

Infarct size reduction in patients with STEMI: why we can do it!

artículo científico

Influence of afterload on left ventricular radial and longitudinal systolic functions: a two-dimensional strain imaging study

scientific article published on 07 August 2009

Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion

artículo científico publicado en 2008

Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice

artículo científico publicado en 2007

Inhibition of mitochondrial permeability transition pore opening: translation to patients

scientific article published on 16 February 2009

Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study

scientific article published on 28 April 2010

Involvement of Cyclophilin D and Calcium in Isoflurane-induced Preconditioning.

artículo científico publicado en 2015

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

artículo científico publicado en 2016

Ischaemic postconditioning reduces infarct size: systematic review and meta-analysis of randomized controlled trials.

artículo científico publicado en 2014

Longitudinal strain quantitates regional right ventricular contractile function

artículo científico publicado en 2003

Melatonin as a cardioprotective therapy following ST-segment elevation myocardial infarction: is it really promising? Reply.

artículo científico publicado en 2017

Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury.

artículo científico publicado en 2010

Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties

artículo científico publicado en 2017

Minor Changes in Core Temperature Prior to Cardiac Arrest Influence Outcomes: An Experimental Study

artículo científico publicado en 2014

Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

artículo científico publicado en 2014

Mitochondrial permeability transition pore and postconditioning

artículo científico publicado en 2006

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week

scientific article published on 01 January 2019

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop

artículo científico publicado en 2011

Non-beating HL-1 cells for confocal microscopy: application to mitochondrial functions during cardiac preconditioning

artículo científico publicado en 2005

Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

artículo científico publicado en 2017

Novel therapeutic strategies for cardioprotection.

artículo científico

Opposite and tissue-specific effects of coenzyme Q2 on mPTP opening and ROS production between heart and liver mitochondria: role of complex I.

artículo científico publicado en 2012

PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning

artículo científico publicado en 2005

Paradoxical toxicity of cardioplegic compounds on ischemic cardiomyocyte using optimal design strategy

artículo científico publicado en 2005

Persistent inhibition of mitochondrial permeability transition by preconditioning during the first hours of reperfusion

artículo científico publicado en 2008

Pharmacological approaches to reperfusion therapy.

artículo científico

Post-conditioning protects from cardioplegia and cold ischemia via inhibition of mitochondrial permeability transition pore

scientific article published on 16 April 2007

Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

scientific article published on 06 May 2010

Postconditioning in acute myocardial infarction patients.

scientific article published on 06 October 2010

Postconditioning in man.

artículo científico publicado en 2007

Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential.

artículo científico publicado en 2009

Postconditioning inhibits mitochondrial permeability transition

scientific article published on 10 January 2005

Postconditioning the Heart of ST-Elevation Myocardial Infarction Patients ⬇️

artículo científico publicado el 9 de abril de 2013

Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition

artículo científico publicado en 2015

Postconditioning: From the Bench to Bedside ⬇️

artículo científico publicado el 11 de octubre de 2010

Postconditioning: from experimental proof to clinical concept

artículo científico publicado en 2010

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

artículo científico publicado en 2018

Preconditioning delays Ca2+-induced mitochondrial permeability transition

artículo científico publicado en 2004

Preservation of ischemia and isoflurane-induced preconditioning after brain death in rabbit hearts.

artículo científico publicado en 2002

RETRACTED: Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K+ channels.

artículo científico publicado en 2012

Regional myocardial function after myocardial infarction in mice: a follow-up study by strain rate imaging

artículo científico publicado en 2009

Revisiting myocardial necrosis biomarkers: assessment of the effect of conditioning therapies on infarct size by kinetic modelling

artículo científico publicado en 2017

Right isovolumic contraction velocity predicts survival in pulmonary hypertension

artículo científico

Second-generation sulfonylureas preserve inhibition of mitochondrial permeability transition by the mitochondrial K+(ATP) opener nicorandil in experimental myocardial infarction

artículo científico publicado en 2009

Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury

artículo científico publicado en 2005

Stable myocardial function and endocrine dysfunction during experimental brain death

artículo científico publicado en 2005

Strain-Rate Imaging Predicts the Attenuation of Left Ventricular Remodeling Induced by Ischemic Postconditioning After Myocardial Infarction in Mice

artículo científico publicado en 2011

Synergistic protective effect of cyclosporin A and rotenone against hypoxia–reoxygenation in cardiomyocytes ⬇️

artículo científico publicado el 10 de diciembre de 2012

Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations.

artículo científico publicado en 2017

Therapeutic Hypothermia After Cardiac Arrest: Involvement of the Risk Pathway in Mitochondrial PTP-Mediated Neuroprotection

artículo científico publicado en 2019

Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.

artículo científico

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

artículo científico publicado en 2010

Trials, tribulations and speculation! Report from the 7th Biennial Hatter Cardiovascular Institute Workshop

artículo científico publicado en 2012

Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury

artículo científico publicado en 2005

Ubiquitous protective effects of cyclosporine A in preventing cardiac arrest-induced multiple organ failure

artículo científico publicado en 2014

Unacylated ghrelin analog prevents myocardial reperfusion injury independently of permeability transition pore

artículo científico publicado en 2016

p53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice

artículo científico publicado en 2012

Lista de obras de

A Dynamic Transcriptional Analysis Reveals IL-6 Axis as a Prominent Mediator of Surgical Acute Response in Non-ischemic Mouse Heart

Acute myocardial infarction in mice: assessment of transmurality by strain rate imaging

An optimal experimental design for the development of preservative heart solutions

Brain death does not change epicardial action potentials and their response to ischemia-reperfusion in open-chest pigs.

Brain death provokes very acute alteration in myocardial morphology detected by echocardiography: preventive effect of beta-blockers

Cardiac fibroblasts protect cardiomyocytes against lethal ischemia-reperfusion injury.

Cardioprotection in the clinical setting

Cardioprotective effect of VEGF and venom VEGF-like protein in acute myocardial ischemia in mice: effect on mitochondrial function

Ceramide in the antiapoptotic effect of ischemic preconditioning

Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials.

Critical appraisal of STAT3 pattern in adult cardiomyocytes

Cyclophilin D and myocardial ischemia-reperfusion injury: a fresh perspective.

Cyclosporine A at reperfusion fails to reduce infarct size in the in vivo rat heart

Cyclosporine A, a Potential Therapy of Ischemic Reperfusion Injury. A Common History for Heart and Brain

Cyclosporine before PCI in Patients with Acute Myocardial Infarction

Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention

Delayed low pressure at reperfusion: A new approach for cardioprotection.

Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury.

Desflurane-induced preconditioning alters calcium-induced mitochondrial permeability transition.

Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening ⬇️

Determination of the myocardial area at risk after reperfused acute myocardial infarction with different imaging techniques: cardiac magnetic resonance imaging, multidetector computed tomography and histopathological validation

Determination of the myocardial area at risk with pre- versus post-reperfusion imaging techniques in the pig model

Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance.

Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice.

ER stress inhibits neuronal death by promoting autophagy

ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies

Effect of Cyclosporine in Nonshockable Out-of-Hospital Cardiac Arrest: The CYRUS Randomized Clinical Trial

Effect of Cyclosporine on Lesion Growth and Infarct Size within the White and Gray Matter.

Efficient and non-toxic gene transfer to cardiomyocytes using novel generation amplicon vectors derived from HSV-1.

Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition ⬇️

Evaluation of cyclosporine A in a stroke model in the immature rat brain

Evolving therapies for myocardial ischemia/reperfusion injury.

Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition

Formation of palmitic acid/Ca2+ complexes in the mitochondrial membrane: a possible role in the cyclosporin-insensitive permeability transition

Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model.

Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts

Infarct size reduction in patients with STEMI: why we can do it!

Influence of afterload on left ventricular radial and longitudinal systolic functions: a two-dimensional strain imaging study

Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion

Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice

Inhibition of mitochondrial permeability transition pore opening: translation to patients

Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study

Involvement of Cyclophilin D and Calcium in Isoflurane-induced Preconditioning.

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

Ischaemic postconditioning reduces infarct size: systematic review and meta-analysis of randomized controlled trials.

Longitudinal strain quantitates regional right ventricular contractile function

Melatonin as a cardioprotective therapy following ST-segment elevation myocardial infarction: is it really promising? Reply.

Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury.

Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties

Minor Changes in Core Temperature Prior to Cardiac Arrest Influence Outcomes: An Experimental Study

Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

Mitochondrial permeability transition pore and postconditioning

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop

Non-beating HL-1 cells for confocal microscopy: application to mitochondrial functions during cardiac preconditioning

Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

Novel therapeutic strategies for cardioprotection.

Opposite and tissue-specific effects of coenzyme Q2 on mPTP opening and ROS production between heart and liver mitochondria: role of complex I.

PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning

Paradoxical toxicity of cardioplegic compounds on ischemic cardiomyocyte using optimal design strategy

Persistent inhibition of mitochondrial permeability transition by preconditioning during the first hours of reperfusion

Pharmacological approaches to reperfusion therapy.

Post-conditioning protects from cardioplegia and cold ischemia via inhibition of mitochondrial permeability transition pore

Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

Postconditioning in acute myocardial infarction patients.

Postconditioning in man.

Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential.

Postconditioning inhibits mitochondrial permeability transition

Postconditioning the Heart of ST-Elevation Myocardial Infarction Patients ⬇️

Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition

Postconditioning: From the Bench to Bedside ⬇️

Postconditioning: from experimental proof to clinical concept

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

Preconditioning delays Ca2+-induced mitochondrial permeability transition

Preservation of ischemia and isoflurane-induced preconditioning after brain death in rabbit hearts.

RETRACTED: Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K+ channels.

Regional myocardial function after myocardial infarction in mice: a follow-up study by strain rate imaging

Revisiting myocardial necrosis biomarkers: assessment of the effect of conditioning therapies on infarct size by kinetic modelling

Right isovolumic contraction velocity predicts survival in pulmonary hypertension