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A novel synthetic quinolinone inhibitor presents proteolytic and hemorrhagic inhibitory activities against snake venom metalloproteases.

artículo científico publicado en 2015

Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I--gene expression profile of highly expressed phospholipases A2.

artículo científico publicado en 2004

Anti-platelet aggregation activity of two novel acidic Asp49-phospholipases A2 from Bothrops brazili snake venom

artículo científico publicado en 2017

Antitumoral Potential of Snake Venom Phospholipases A2 and Synthetic Peptides

artículo científico publicado en 2016

Antitumoral activity of snake venom proteins: new trends in cancer therapy

artículo científico publicado en 2014

Bhalternin: Functional and structural characterization of a new thrombin-like enzyme from Bothrops alternatus snake venom.

artículo científico publicado en 2010

Biochemical and functional characterization of Parawixia bistriata spider venom with potential proteolytic and larvicidal activities

artículo científico publicado en 2014

Biochemical characterization of a phospholipase A2 homologue from the venom of the social wasp Polybia occidentalis.

artículo científico publicado en 2018

Biodegradable microparticles containing crotamine isolated from Crotalus durissus terrificus display antileishmanial activity in vitro

artículo científico publicado en 2015

Biodiversity as a source of bioactive compounds against snakebites

artículo científico publicado en 2014

Biological characterization of the Amazon coral Micrurus spixii snake venom: Isolation of a new neurotoxic phospholipase A2.

artículo científico publicado en 2015

BmajPLA2-II, a basic Lys49-phospholipase A2 homologue from Bothrops marajoensis snake venom with parasiticidal potential.

artículo científico publicado en 2017

Camelid Single-Domain Antibodies (VHHs) against Crotoxin: A Basis for Developing Modular Building Blocks for the Enhancement of Treatment or Diagnosis of Crotalic Envenoming.

artículo científico publicado en 2018

Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological properties

artículo científico publicado en 2003

Cloning and expression of an acidic platelet aggregation inhibitor phospholipase A2 cDNA from Bothrops jararacussu venom gland.

artículo científico publicado en 2004

Comparative venomics of Brazilian coral snakes: Micrurus frontalis, Micrurus spixii spixii, and Micrurus surinamensis

scientific article published on 12 May 2019

Comparative venomics of Brazilian coral snakes: Micrurus frontalis, Micrurus spixii spixii, and Micrurus surinamensis

scientific article published on 01 April 2020

Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s

artículo científico publicado en 2010

Cross-reactivity and inhibition myotoxic effects induced by Bothrops snake venoms using specific polyclonal anti-BnSP7 antibodies

artículo científico publicado en 2017

Crotalus durissus collilineatus venom gland transcriptome: analysis of gene expression profile

artículo científico publicado en 2009

Crystal structure of a myotoxic Asp49-phospholipase A2 with low catalytic activity: Insights into Ca2+-independent catalytic mechanism

artículo científico publicado en 2008

Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity

artículo científico publicado en 2009

Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A2: quaternary structure and inhibition mechanism insights

artículo científico publicado el 21 de noviembre de 2003

Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A2 complexed with alpha-tocopherol

artículo científico publicado en 2005

Danger in the canopy. Comparative proteomics and bioactivities of the venoms of the South American palm pitviper Bothrops bilineatus subspecies bilineatus and smaragdinus, and antivenomics of B. b. bilineatus (Rondônia) venom against the Brazilian p

artículo científico publicado en 2020

Enzymatic and structural characterization of a basic phospholipase A2 from the sea anemone Condylactis gigantea

scientific article published on 26 May 2010

Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract

artículo científico publicado en 2013

Expression of human recombinant antibody fragments capable of partially inhibiting the phospholypase activity of Crotalus durissus terrificus venom

artículo científico publicado en 2009

Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments.

artículo científico publicado en 2016

Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti

artículo científico publicado en 2014

Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom

artículo científico publicado en 2008

Isolation and biochemical characterization of a new thrombin-like serine protease from Bothrops pirajai snake venom

artículo científico publicado en 2014

Isolation and expression of a hypotensive and anti-platelet acidic phospholipase A2 from Bothrops moojeni snake venom

artículo científico publicado en 2012

Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity

artículo científico publicado en 2020

Isolation, structural and functional characterization of a new Lys49 phospholipase A2 homologue from Bothrops neuwiedi urutu with bactericidal potential.

artículo científico publicado en 2016

Liposomes containing an ASP49-phospholipase A2 from Bothrops jararacussu snake venom as experimental therapy against cutaneous leishmaniasis.

artículo científico publicado en 2016

Mechanism of the cytotoxic effect of l-amino acid oxidase isolated from Bothrops alternatus snake venom

artículo científico publicado en 2016

Medicinal plants with inhibitory properties against snake venoms

artículo científico publicado en 2005

Molecular approaches for structural characterization of Bothrops L-amino acid oxidases with antiprotozoal activity: cDNA cloning, comparative sequence analysis, and molecular modeling.

artículo científico publicado en 2007

Molecular characterization of an acidic phospholipase A2 from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region

artículo científico publicado el 18 de febrero de 2011

Myotoxic phospholipases A(2) isolated from Bothrops brazili snake venom and synthetic peptides derived from their C-terminal region: cytotoxic effect on microorganism and tumor cells

artículo científico publicado en 2008

Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome

artículo científico publicado en 2014

Pharmacological perspectives of wasp venom

artículo científico publicado en 2009

Phospholipase A2 Inhibitor from Crotalus durissus terrificus rattlesnake: Effects on human peripheral blood mononuclear cells and human neutrophils cells.

artículo científico publicado en 2017

Photobiostimulation reduces edema formation induced in mice by Lys-49 phospholipases A2 isolated from Bothrops moojeni venom.

artículo científico publicado en 2014

Plasmodium falciparum purine nucleoside phosphorylase as a model in the search for new inhibitors by high throughput screening

artículo científico publicado en 2020

Preliminary X-ray crystallographic studies of a Lys49-phospholipase A2 homologue from Bothrops pirajai venom complexed with p-bromo-phenacyl bromide and alpha-tocopherol inhibitors.

artículo científico publicado en 2007

Protective effect of schizolobium parahyba flavonoids against snake venoms and isolated toxins

artículo científico publicado en 2011

Snake Venom, A Natural Library of New Potential Therapeutic Molecules: Challenges and Current Perspectives

artículo científico publicado en 2018

Snake venom L-amino acid oxidases: some consideration about their functional characterization

artículo científico publicado en 2009

Snake venom L-amino acid oxidases: trends in pharmacology and biochemistry

artículo científico publicado en 2014

Snake venom phospholipase A2 inhibitors: medicinal chemistry and therapeutic potential

artículo científico publicado en 2007

Snake venomics and antivenomics of Crotalus durissus subspecies from Brazil: assessment of geographic variation and its implication on snakebite management

artículo científico publicado en 2010

Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids

artículo científico publicado en 2015

Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition

artículo científico publicado en 2011

Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A₂-like

artículo científico publicado en 2013

Structural and phylogenetic studies with MjTX-I reveal a multi-oligomeric toxin--a novel feature in Lys49-PLA2s protein class

artículo científico publicado en 2013

Structural bases for a complete myotoxic mechanism: crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom

artículo científico publicado en 2013

Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A₂ class

artículo científico publicado en 2011

The effect of 3β, 6β, 16β-trihydroxylup-20(29)-ene lupane compound isolated from Combretum leprosum Mart. on peripheral blood mononuclear cells.

artículo científico publicado en 2015

Tityus serrulatus scorpion venom and toxins: an overview

artículo científico publicado en 2009

Venomics and antivenomics of the poorly studied Brazil's lancehead, Bothrops brazili (Hoge, 1954), from the Brazilian State of Pará

artículo científico publicado en 2020

cDNA sequence and molecular modeling of a nerve growth factor from Bothrops jararacussu venomous gland

artículo científico publicado en 2002