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ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

artículo científico publicado en 2016

Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference

artículo científico publicado en 2016

Alemtuzumab in combination with methylprednisolone is a highly effective induction regimen for patients with chronic lymphocytic leukemia and deletion of TP53: final results of the national cancer research institute CLL206 trial

artículo científico publicado en 2012

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

artículo científico publicado en 2011

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

artículo científico publicado en 2002

Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data

artículo científico publicado en 2014

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

artículo científico publicado en 2017

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

artículo científico publicado en 2014

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

artículo científico publicado en 2010

Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact

scientific article published on 02 January 2019

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

artículo científico publicado en 2015

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

artículo científico publicado en 2016

Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia

artículo científico publicado en 2002

Exome sequence read depth methods for identifying copy number changes

artículo científico publicado en 2014

Functional analysis of the ATM-p53-p21 pathway in the LRF CLL4 trial: blockade at the level of p21 is associated with short response duration.

artículo científico publicado en 2012

Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing

artículo científico publicado en 2015

Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study

scientific article published on 23 January 2020

Guidelines on the diagnosis, investigation and management of chronic lymphocytic leukaemia

artículo científico publicado en 2012

Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: results from the LRF CLL4 trial

artículo científico publicado en 2011

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy

artículo científico publicado en 2017

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

artículo científico publicado en 2014

Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation

artículo científico publicado en 2010

Rituximab plus chlorambucil as first-line treatment for chronic lymphocytic leukemia: Final analysis of an open-label phase II study

artículo científico publicado en 2014

Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia

artículo científico publicado en 2018

The frequency ofTP53gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors

article

The morphology of CLL revisited: the clinical significance of prolymphocytes and correlations with prognostic/molecular markers in the LRF CLL4 trial

scientific article published on 06 May 2016

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.

artículo científico publicado en 2013

Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events

scientific article published on 01 August 2002

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma

artículo científico publicado en 2013

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

artículo científico publicado en 2015

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