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A simple transcriptomic signature able to predict drug-induced hepatic steatosis.

artículo científico publicado en 2014

Cytometric analysis for drug-induced steatosis in HepG2 cells.

artículo científico publicado en 2009

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

artículo científico publicado en 2003

Establishment and characterization of immortal hepatocytes derived from various transgenic mouse lines.

artículo científico publicado en 2002

HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.

artículo científico publicado en 2013

High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins

scientific article published on 27 August 2014

Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.

artículo científico publicado en 2016

LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells.

artículo científico publicado en 2015

Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes

scientific article published on 13 November 2018

Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts

artículo científico publicado en 2006

Transcriptional regulation and expression of CYP3A4 in hepatocytes.

artículo científico publicado en 2007