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A novel method for sample preparation of fresh lung cancer tissue for proteomics analysis by tumor cell enrichment and removal of blood contaminants

artículo científico publicado en 2010

Activity of hydrolytic enzymes in tumour cells is a determinant for anti-tumour efficacy of the melphalan containing prodrug J1.

artículo científico publicado en 2003

Affinity prefractionation for MS-based plasma proteomics

artículo científico publicado en 2009

Annotated regions of significance of SELDI-TOF-MS spectra for detecting protein biomarkers

artículo científico publicado en 2006

Antitumor activity of the alkylating oligopeptides J1 (L-melphalanyl-p-L-fluorophenylalanine ethyl ester) and P2 (L-prolyl-m-L-sarcolysyl-p-L-fluorophenylalanine ethyl ester): comparison with melphalan

artículo científico publicado el 1 de septiembre de 2003

Antitumor activity of the novel melphalan containing tripeptide J3 (L-prolyl-L-melphalanyl-p-L-fluorophenylalanine ethyl ester): comparison with its m-L-sarcolysin analogue P2.

artículo científico publicado en 2003

Antitumor efficacy and acute toxicity of the novel dipeptide melphalanyl-p-L-fluorophenylalanine ethyl ester (J1) in vivo

artículo científico publicado en 2004

Evaluation of three principally different intact protein prefractionation methods for plasma biomarker discovery.

artículo científico publicado en 2008

Preclinical activity of melflufen (J1) in ovarian cancer

scientific article published on 09 August 2016

Proteomic data analysis workflow for discovery of candidate biomarker peaks predictive of clinical outcome for patients with acute myeloid leukemia

artículo científico publicado en 2008

Quantitative proteomics profiling of primary lung adenocarcinoma tumors reveals functional perturbations in tumor metabolism

artículo científico publicado en 2013

Structure-activity relationship for alkylating dipeptide nitrogen mustard derivatives.

artículo científico publicado en 2003

Tumor expression of S100A6 correlates with survival of patients with stage I non-small-cell lung cancer

artículo científico publicado en 2008

Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling

artículo científico publicado en 2007

Use of narrow-range peptide IEF to improve detection of lung adenocarcinoma markers in plasma and pleural effusion

artículo científico publicado en 2009