Lista de obras -

A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction

artículo científico publicado en 2009

A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen

artículo científico publicado en 2013

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.

artículo científico publicado en 2014

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies

artículo científico publicado en 2009

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells

artículo científico publicado en 2009

BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid

artículo científico publicado en 2014

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding

artículo científico publicado en 2006

Chromatin organization at the nuclear pore favours HIV replication

artículo científico publicado en 2015

Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp

artículo científico publicado en 2007

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

artículo científico publicado en 2015

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

artículo científico publicado en 2011

Contribution of MxB oligomerization to HIV-1 capsid binding and restriction

artículo científico publicado en 2015

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1 ⬇️

artículo científico publicado el 13 de noviembre de 2012

Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.

artículo científico publicado en 2012

Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration.

artículo científico publicado en 2013

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

artículo científico publicado en 2016

Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility.

artículo científico publicado en 2014

Endocytosis is a critical step in entry of subgroup B avian leukosis viruses.

artículo científico publicado en 2002

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

artículo científico publicado en 2015

HIV-1 uncoating is facilitated by dynein and kinesin 1

artículo científico publicado en 2014

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

artículo científico publicado en 2012

Identification and characterization of naturally occurring splice variants of SAMHD1 ⬇️

artículo científico publicado el 23 de octubre de 2012

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1

artículo científico publicado en 2014

Inhibition of Reverse Transcriptase Activity Increases Stability of the HIV-1 Core ⬇️

artículo científico publicado el 17 de octubre de 2012

Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particles

artículo científico publicado en 2008

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.

artículo científico publicado en 2017

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain

artículo científico publicado en 2007

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

artículo científico publicado en 2014

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

artículo científico publicado en 2013

Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection

artículo científico publicado en 2009

Preferential lentiviral targeting of astrocytes in the central nervous system

artículo científico publicado en 2013

Proceedings of the Frontiers of Retrovirology Conference 2016.

artículo científico publicado en 2016

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

artículo científico publicado en 2015

RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating

artículo científico publicado en 2011

Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.

artículo científico publicado en 2006

Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.

artículo científico publicado en 2006

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

artículo científico publicado en 2015

Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region.

artículo científico publicado en 2014

Retroviral restriction factor TRIM5alpha is a trimer

artículo científico publicado en 2005

Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core

artículo científico publicado en 2013

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac ⬇️

artículo científico publicado el 12 de junio de 2012

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

artículo científico publicado en 2016

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

artículo científico publicado en 2006

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

artículo científico publicado en 2014

Structure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition module

artículo científico publicado en 2012

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

artículo científico publicado en 2012

TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity

artículo científico publicado en 2005

The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation ⬇️

artículo científico publicado el 17 de abril de 2013

The Role of TNPO3 in HIV-1 Replication ⬇️

artículo científico publicado el 19 de julio de 2012

The ability of multimerized cyclophilin A to restrict retrovirus infection

artículo científico publicado en 2007

The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha

artículo científico publicado en 2005

The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating

artículo científico publicado en 2014

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

scientific journal article

Trafficking of some old world primate TRIM5α proteins through the nucleus ⬇️

artículo científico publicado el 15 de mayo de 2011

Unique features of TRIM5alpha among closely related human TRIM family members

artículo científico publicado en 2007

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.

artículo científico publicado en 2014

Lista de obras de

A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction

A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells

BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding

Chromatin organization at the nuclear pore favours HIV replication

Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

Contribution of MxB oligomerization to HIV-1 capsid binding and restriction

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1 ⬇️

Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.

Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility.

Endocytosis is a critical step in entry of subgroup B avian leukosis viruses.

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

HIV-1 uncoating is facilitated by dynein and kinesin 1

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

Identification and characterization of naturally occurring splice variants of SAMHD1 ⬇️

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1

Inhibition of Reverse Transcriptase Activity Increases Stability of the HIV-1 Core ⬇️

Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particles

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection

Preferential lentiviral targeting of astrocytes in the central nervous system

Proceedings of the Frontiers of Retrovirology Conference 2016.

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating

Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.

Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region.

Retroviral restriction factor TRIM5alpha is a trimer

Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac ⬇️

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

Structure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition module

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity

The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation ⬇️

The Role of TNPO3 in HIV-1 Replication ⬇️

The ability of multimerized cyclophilin A to restrict retrovirus infection

The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha

The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

Trafficking of some old world primate TRIM5α proteins through the nucleus ⬇️

Unique features of TRIM5alpha among closely related human TRIM family members

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.