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A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485.

artículo científico publicado en 2018

A novel ultrasensitive hybridization-based ELISA method for 2-methoxyphosphorothiolate microRNAs and its in vitro and in vivo application

artículo científico publicado en 2010

Author Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

artículo científico publicado en 2020

Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia

artículo científico publicado en 2007

CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia

artículo científico publicado en 2013

Clinical and functional significance of circular RNAs in cytogenetically normal AML

scientific article published on 01 January 2020

Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia

artículo científico publicado en 2012

Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine

artículo científico publicado en 2010

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients

artículo científico publicado en 2013

Discovery and functional implications of a miR-29b-1/miR-29a cluster polymorphism in acute myeloid leukemia

artículo científico publicado en 2017

Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia

artículo científico publicado en 2016

Dose escalation of lenalidomide in relapsed or refractory acute leukemias

artículo científico publicado en 2010

EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia

artículo científico publicado en 2019

Elucidating the role of the long non-coding RNA dancr in leukemic stem cells in acute myeloid leukemia (AML)

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

artículo científico publicado en 2013

Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells

scientific article published on 11 March 2019

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

artículo científico publicado en 2014

Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profiling

artículo científico publicado en 2011

Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia

artículo científico publicado en 2012

Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML.

artículo científico publicado en 2014

Improved nonrelapse mortality and infection rate with lower dose of antithymocyte globulin in patients undergoing reduced-intensity conditioning allogeneic transplantation for hematologic malignancies

scientific article published on September 2009

In vivo quantification of active decitabine-triphosphate metabolite: a novel pharmacoanalytical endpoint for optimization of hypomethylating therapy in acute myeloid leukemia

artículo científico publicado en 2012

Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia

artículo científico publicado en 2012

MicroRNA 29b functions in acute myeloid leukemia

artículo científico publicado en 2009

MicroRNA expression in cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2008

MicroRNA fingerprints during human megakaryocytopoiesis

artículo científico publicado en 2006

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

artículo científico publicado en 2008

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

artículo científico publicado en 2009

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia

scientific article published on 14 August 2019

PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells

artículo científico publicado en 2013

Pharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia

artículo científico publicado en 2013

Phase I study of azacitidine and bortezomib in adults with relapsed or refractory acute myeloid leukemia

artículo científico publicado en 2013

Pluripotent stem cell miRNAs and metastasis in invasive breast cancer

artículo científico publicado en 2014

Prognostic and Biologic Relevance of Clinically Applicable Long Noncoding RNA Profiling in Older Patients with Cytogenetically Normal Acute Myeloid Leukemia

artículo científico publicado en 2019

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

artículo científico

Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia

artículo científico publicado en 2017

Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

artículo científico publicado en 2010

Publisher Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 07 January 2020

Regulation of acute graft-versus-host disease by microRNA-155.

artículo científico publicado en 2012

Reprogramming of miRNA networks in cancer and leukemia

artículo científico publicado en 2010

SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

artículo científico publicado en 2014

Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

artículo científico publicado en 2013

Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia

artículo científico publicado en 2010

Synthetic microRNA cassette dosing: pharmacokinetics, tissue distribution and bioactivity

artículo científico publicado en 2012

Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia

artículo científico publicado en 2013

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 25 November 2019