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A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three brain metastases from solid tumors after surgical resection or radiosurgery: quality-o

artículo científico publicado en 2012

A Systematic Review and Recommendation for Reporting of Surrogate Endpoint Evaluation Using Meta-analyses

artículo científico publicado en 2019

A multinational, multi-tumour basket study in very rare cancer types: The European Organization for Research and Treatment of Cancer phase II 90101 'CREATE' trial

scientific article published on 14 January 2019

A new measure of treatment effect in clinical trials involving competing risks based on generalized pairwise comparisons

scientific article published on 16 September 2020

Adjuvant Chemotherapy for Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis of Individual Participant Data from Randomised Controlled Trials

artículo científico publicado en 2022

Adjuvant Gemcitabine Alone Versus Gemcitabine-Based Chemoradiotherapy After Curative Resection for Pancreatic Cancer: A Randomized EORTC-40013-22012/FFCD-9203/GERCOR Phase II Study ⬇️

artículo científico publicado el 13 de septiembre de 2010

Adjuvant Radiotherapy After Surgery for Pathologically Advanced Prostate Cancer

artículo científico publicado en 2007

Adjuvant chemotherapy after preoperative (chemo)radiotherapy and surgery for patients with rectal cancer: a systematic review and meta-analysis of individual patient data

artículo científico publicado en 2015

Adjuvant chemotherapy for rectal cancer--authors' reply

artículo científico publicado en 2014

Adjuvant postoperative high-dose radiotherapy for atypical and malignant meningioma: A phase-II parallel non-randomized and observation study (EORTC 22042-26042)

scientific article published on 28 June 2018

Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study

artículo científico publicado en 2010

Analysing data from patient-reported outcome and quality of life endpoints for cancer clinical trials: a start in setting international standards ⬇️

artículo científico publicado en 2016

Are prostate-specific antigen changes valid surrogates for survival in hormone-refractory prostate cancer? A meta-analysis is needed!

artículo científico publicado en 2007

Association of Gleason Grade With Androgen Deprivation Therapy Duration and Survival Outcomes: A Systematic Review and Patient-Level Meta-analysis

artículo científico publicado en 2019

BPA uptake does not correlate with LAT1 and Ki67 expressions in tumor samples (results of EORTC trial 11001)

artículo científico publicado en 2011

Bone marrow MRI versus 18F-FDG-PET/CT for detecting multiple myeloma lesions: diagnostic performance and clinical relevance ⬇️

scholarly article

CMET-43. COMPARISON OF LOCAL CONTROL OF BRAIN METASTASES WITH STEREOTACTIC RADIOSURGERY VERSUS SURGICAL RESECTION: A SECONDARY ANALYSIS OF EORTC 22952–26001

Can radical prostatectomy benefit patients despite the presence of regional metastases?

artículo científico publicado en 2010

Can whole-body magnetic resonance imaging with diffusion-weighted imaging replace Tc 99m bone scanning and computed tomography for single-step detection of metastases in patients with high-risk prostate cancer?

artículo científico publicado en 2012

Characterisation and classification of oligometastatic disease: a European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of Cancer consensus recommendation

scientific article published on 01 January 2020

Chemotherapy with preoperative radiotherapy in rectal cancer

artículo científico publicado en 2006

Clinical trial designs for predictive marker validation in cancer treatment trials

artículo científico publicado en 2005

Collaboration between EORTC and JCOG-how to accelerate global clinical research partnership

artículo científico publicado en 2017

Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial

scientific article published on 01 February 2019

Comparison of Local Control of Brain Metastases With Stereotactic Radiosurgery vs Surgical Resection: A Secondary Analysis of a Randomized Clinical Trial

scientific article published on 01 February 2019

Cumulative Toxicity in Targeted Therapies: What to Expect at the Recommended Phase II Dose

scientific article published on 01 November 2019

Defining dose-limiting toxicity for phase 1 trials of molecularly targeted agents: results of a DLT-TARGETT international survey

artículo científico publicado en 2014

Differences in time to disease progression do not predict for cancer-specific survival in patients receiving immediate or deferred androgen-deprivation therapy for prostate cancer: final results of EORTC randomized trial 30891 with 12 years of follo

artículo científico publicado en 2013

Does local treatment of the prostate in advanced and/or lymph node metastatic disease improve efficacy of androgen-deprivation therapy? A systematic review

artículo científico publicado en 2010

Dose-Finding Methods: Moving Away from the 3 + 3 to Include Richer Outcomes.

artículo científico publicado en 2017

Dummy run and conformity indices in the ongoing EORTC low-grade glioma trial 22033-26033: First evaluation of quality of radiotherapy planning.

artículo científico publicado en 2010

Duration of androgen suppression in the treatment of prostate cancer

artículo científico publicado en 2009

EORTC 22972-26991/MRC BR10 trial: fractionated stereotactic boost following conventional radiotherapy of high grade gliomas. Clinical and quality-assurance results of the stereotactic boost arm.

artículo científico publicado en 2008

EORTC Nomograms and Risk Groups for Predicting Recurrence, Progression, and Disease-specific and Overall Survival in Non-Muscle-invasive Stage Ta-T1 Urothelial Bladder Cancer Patients Treated with 1-3 Years of Maintenance Bacillus Calmette-Guérin.

artículo científico publicado en 2015

EORTC prostate cancer trials: what have we learnt?

artículo científico publicado en 2002

EORTC trial 11001: distribution of two 10B-compounds in patients with squamous cell carcinoma of head and neck, a translational research/phase 1 trial.

artículo científico publicado en 2009

EORTC-ROG expert opinion: radiotherapy volume and treatment guidelines for neoadjuvant radiation of adenocarcinomas of the gastroesophageal junction and the stomach

artículo científico publicado en 2009

ESMO-MCBS: setting the record straight - Authors' reply

artículo científico publicado en 2019

Early versus delayed endocrine treatment of T2-T3 pN1-3 M0 prostate cancer without local treatment of the primary tumour: final results of European Organisation for the Research and Treatment of Cancer protocol 30846 after 13 years of follow-up (a r

artículo científico publicado en 2008

Early versus delayed endocrine treatment of pN1-3 M0 prostate cancer without local treatment of the primary tumor: results of European Organisation for the Research and Treatment of Cancer 30846--a phase III study

artículo científico publicado en 2004

Editorial comment

artículo científico publicado en 2009

Effect of age and radiation dose on local control after breast conserving treatment: EORTC trial 22881-10882.

artículo científico publicado en 2006

Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.

artículo científico publicado en 2005

European Organisation of Research and Treatment of Cancer (EORTC) Gastrointestinal Group: Workshop on the role of metabolic imaging in the neoadjuvant treatment of gastrointestinal cancer

artículo científico publicado en 2008

Event-Free Survival, a Prostate-Specific Antigen-Based Composite End Point, Is Not a Surrogate for Overall Survival in Men With Localized Prostate Cancer Treated With Radiation

scientific article published on 18 June 2020

Expression of the androgen-regulated fusion gene TMPRSS2-ERG does not predict response to endocrine treatment in hormone-naïve, node-positive prostate cancer

artículo científico publicado en 2009

External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study.

artículo científico publicado en 2010

Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study

artículo científico publicado en 2014

From a Comic Opera to Surcare an Open Letter to Whom Clinical Research in Surgery Is a Concern: Announcing the Launch of SURCARE

artículo científico publicado en 2016

Guidelines for time-to-event end-point definitions in trials for pancreatic cancer. Results of the DATECAN initiative (Definition for the Assessment of Time-to-event End-points in CANcer trials).

artículo científico publicado en 2014

Identification of patients with prostate cancer who benefit from immediate postoperative radiotherapy: EORTC 22911.

artículo científico publicado en 2007

Immediate or deferred androgen deprivation for patients with prostate cancer not suitable for local treatment with curative intent: European Organisation for Research and Treatment of Cancer (EORTC) Trial 30891

artículo científico publicado en 2006

Immediate versus deferred chemotherapy after radical cystectomy in patients with pT3-pT4 or N+ M0 urothelial carcinoma of the bladder (EORTC 30994): an intergroup, open-label, randomised phase 3 trial

artículo científico publicado en 2014

Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial

artículo científico publicado en 2007

Impact of acute kidney injury on anticancer treatment dosage and long-term outcomes: a pooled analysis of European Organisation for Research and Treatment of Cancer trials

artículo científico publicado en 2020

Impact of pathological characteristics on local relapse after breast-conserving therapy: a subgroup analysis of the EORTC boost versus no boost trial

artículo científico publicado en 2009

Impact of pathology review of stage and margin status of radical prostatectomy specimens (EORTC trial 22911).

artículo científico publicado en 2006

Impact of primary tumor location on survival from EORTC advanced urothelial cancer studies.

artículo científico publicado en 2017

Impact of the COVID-19 crisis on imaging in oncological trials

artículo científico publicado en 2020

Impact of the boost dose of 10 Gy versus 26 Gy in patients with early stage breast cancer after a microscopically incomplete lumpectomy: 10-year results of the randomised EORTC boost trial

artículo científico publicado en 2008

Implications of prostate-specific antigen doubling time as indicator of failure after surgery or radiation therapy for prostate cancer

artículo científico publicado en 2006

In Reply:

Intermittent maximal androgen blockade in patients with metastatic prostate cancer: an EORTC feasibility study

artículo científico publicado en 2003

Internal Mammary and Medial Supraclavicular Irradiation in Breast Cancer

artículo científico publicado en 2015

International evaluation of the psychometrics of health-related quality of life questionnaires for use among long-term survivors of testicular and prostate cancer ⬇️

artículo científico publicado en 2017

International standards for the analysis of quality-of-life and patient-reported outcome endpoints in cancer randomised controlled trials: recommendations of the SISAQOL Consortium

artículo científico publicado en 2020

Is baseline quality of life useful for predicting survival with hormone-refractory prostate cancer? A pooled analysis of three studies of the European Organisation for Research and Treatment of Cancer Genitourinary Group

artículo científico publicado en 2004

Is prostate-specific antigen a valid surrogate end point for survival in hormonally treated patients with metastatic prostate cancer? Joint research of the European Organisation for Research and Treatment of Cancer, the Limburgs Universitair Centrum

artículo científico publicado en 2005

Late toxicity following conventional radiotherapy for prostate cancer: analysis of the EORTC trial 22863

Local Failure and Survival After Definitive Radiotherapy for Aggressive Prostate Cancer: An Individual Patient-level Meta-analysis of Six Randomized Trials

artículo científico publicado en 2019

Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial

artículo científico publicado en 2002

MRI versus 18F-FDG-PET/CT for detecting bone marrow involvement in multiple myeloma: diagnostic performance and clinical relevance

scientific article published on 16 December 2019

Metastasis-Free Survival Is a Strong Surrogate of Overall Survival in Localized Prostate Cancer

artículo científico

Metastatic prostate cancer treated by flutamide versus cyproterone acetate. Final analysis of the "European Organization for Research and Treatment of Cancer" (EORTC) Protocol 30892.

artículo científico publicado en 2004

Morbidity from pelvic lymphadenectomy in men undergoing radical prostatectomy

artículo científico publicado en 2006

Moving forward toward standardizing analysis of quality of life data in randomized cancer clinical trials ⬇️

article by Andrew Bottomley et al published December 2018 in Clinical Trials

N-of-1 trials in oncology

artículo científico publicado en 2015

Nomogram to predict ipsilateral breast relapse based on pathology review from the EORTC 22881-10882 boost versus no boost trial.

artículo científico publicado en 2011

Nomograms for predicting local recurrence, distant metastases, and overall survival for patients with locally advanced rectal cancer on the basis of European randomized clinical trials

artículo científico publicado en 2011

One-step TNM staging of high-risk prostate cancer using magnetic resonance imaging (MRI): toward an upfront simplified "all-in-one" imaging approach?

artículo científico

Overall Survival in Men With Bone Metastases From Castration-Resistant Prostate Cancer Treated With Bone-Targeting Radioisotopes: A Meta-analysis of Individual Patient Data From Randomized Clinical Trials

scientific article published on 12 December 2019

Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

article

P52 Can the forest plot be simplified without loosing relevant information in meta-analyses? ⬇️

scholarly article

Palliative-care trials: how best to publish findings?

artículo científico publicado en 2008

Patients at high risk of progression after radical prostatectomy: do they all benefit from immediate post-operative irradiation? (EORTC trial 22911)

artículo científico publicado en 2005

Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Canc

artículo científico publicado en 2007

Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial

artículo científico publicado en 2008

Pooled Analysis of external-beam RADiotherapy parameters in phase II and phase III trials in radiochemotherapy in Anal Cancer (PARADAC)

artículo científico publicado en 2019

Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911)

scientific article published on 19 October 2012

Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911)

scientific article published on 01 August 2005

Postoperative radiotherapy for high-risk prostate cancer – Authors' reply ⬇️

artículo científico publicado el 30 de marzo de 2013

Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup Trial 40983).

artículo científico publicado en 2012

Predictors of the risk of fibrosis at 10 years after breast conserving therapy for early breast cancer: a study based on the EORTC Trial 22881-10882 'boost versus no boost'

artículo científico publicado en 2008

Profile of European radiotherapy departments contributing to the EORTC Radiation Oncology Group (ROG) in the 21st century

artículo científico publicado en 2008

Prognostic Factors for Local Control in Breast Cancer After Long-term Follow-up in the EORTC Boost vs No Boost Trial: A Randomized Clinical Trial

artículo científico

Prophylactic cranial irradiation in extensive disease small-cell lung cancer: short-term health-related quality of life and patient reported symptoms: results of an international Phase III randomized controlled trial by the EORTC Radiation Oncology a

article

Prophylactic cranial irradiation in extensive small-cell lung cancer

artículo científico publicado en 2007

Proportional odds assumption for modeling longitudinal ordinal multiple toxicity outcomes in dose finding studies of targeted agents: A pooled analysis of 54 studies

artículo científico publicado en 2020

Prostate cancer: to screen or not to screen?

artículo científico publicado en 2009

Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892).

artículo científico publicado en 2003

Prostate-specific antigen (PSA) alone is not an appropriate surrogate marker of long-term therapeutic benefit in prostate cancer trials

artículo científico publicado en 2006

Prostate-specific antigen (PSA) as a surrogate end point for survival in prostate cancer clinical trials

scientific article published on 28 August 2007

Protocol of the Definition for the Assessment of Time-to-event Endpoints in CANcer trials (DATECAN) project: formal consensus method for the development of guidelines for standardised time-to-event endpoints' definitions in cancer clinical trials.

artículo científico publicado en 2012

Quality assurance in breast cancer: EORTC experiences in the phase III trial on irradiation of the internal mammary nodes

scientific article published on 19 January 2007

Quality assurance in the EORTC phase III randomised 'boost vs. no boost' trial for breast conserving therapy: comparison of the results of two individual case reviews performed early and late during the accrual period

artículo científico publicado en 2005

Quality assurance in the EORTC randomized trial 22922/10925 investigating the role of irradiation of the internal mammary and medial supraclavicular lymph node chain works

artículo científico publicado en 2006

Quality assurance of the EORTC 22043-30041 trial in post-operative radiotherapy in prostate cancer: results of the Dummy Run procedure

artículo científico publicado en 2013

Quality of life in good prognosis patients with metastatic germ cell cancer: a prospective study of the European Organization for Research and Treatment of Cancer Genitourinary Group/Medical Research Council Testicular Cancer Study Group (30941/TE20

artículo científico publicado en 2003

Quality of surgery in T3-4 rectal cancer: involvement of circumferential resection margin not influenced by preoperative treatment. Results from EORTC trial 22921

scientific article published on 12 July 2007

Raltitrexed (Tomudex) versus standard leucovorin-modulated bolus 5-fluorouracil: Results from the randomised phase III Pan-European Trial in Adjuvant Colon Cancer 01 (PETACC-1).

artículo científico publicado en 2008

Randomized phase III study comparing paclitaxel-bleomycin, etoposide, and cisplatin (BEP) to standard BEP in intermediate-prognosis germ-cell cancer: intergroup study EORTC 30983.

artículo científico publicado en 2012

Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3.

artículo científico publicado en 2009

Re: Design and endpoints of clinical trials in patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group

artículo científico publicado en 2008

Recruiting long-term survivors of European Organisation for Research and Treatment of Cancer phase III clinical trials into quality of life studies: challenges and opportunities

artículo científico publicado en 2014

Responding to the challenges of international collaborations between the east and the west - report of the first JCOG-EORTC symposium and a perspective from young JCOG and EORTC investigators

artículo científico publicado en 2019

Results of the phase II EORTC 22971 trial evaluating combined accelerated external radiation and chemotherapy with 5FU and cisplatin in patients with muscle invasive transitional cell carcinoma of the bladder

artículo científico publicado en 2008

Robot-assisted cystectomy: does it meet expectations?

artículo científico publicado en 2010

Sample size computation in phase II designs combining the A'Hern design and the Sargent and Goldberg design

artículo científico publicado en 2019

Selection bias is not a good reason for advising more than 5 years of adjuvant hormonal therapy for all patients with locally advanced prostate cancer treated with radiotherapy

artículo científico publicado en 2009

Selection of appropriate end-points (pCR vs 2yDFS) for tailoring treatments with prediction models in locally advanced rectal cancer

artículo científico publicado en 2015

Short Androgen Suppression and Radiation Dose Escalation for Intermediate- and High-Risk Localized Prostate Cancer: Results of EORTC Trial 22991.

artículo científico publicado en 2016

Short- vs long-term androgen suppression plus external beam radiation therapy and survival in men of advanced age with node-negative high-risk adenocarcinoma of the prostate

scientific article published on 01 May 2007

Statistical analysis of patient-reported outcome data in randomised controlled trials of locally advanced and metastatic breast cancer: a systematic review ⬇️

Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME)

scientific article published on 18 June 2019

Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data ⬇️

artículo científico publicado el 14 de mayo de 2013

The abdominoperineal resection itself is associated with an adverse outcome: the European experience based on a pooled analysis of five European randomised clinical trials on rectal cancer

artículo científico publicado en 2009

The influence of the boost technique on local control in breast conserving treatment in the EORTC 'boost versus no boost' randomised trial

artículo científico publicado en 2004

Timing to achieve the highest rate of pCR after preoperative radiochemotherapy in rectal cancer: a pooled analysis of 3085 patients from 7 randomized trials

scientific article published on 20 September 2020

Towards an evidence-informed value scale for surgical and radiation oncology: a multi-stakeholder perspective

artículo científico publicado en 2019

Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents--dose-Limiting Toxicity and Toxicity Assessment Recommendation Group for Early Trials

artículo científico publicado en 2014

Toxicity at three years with and without irradiation of the internal mammary and medial supraclavicular lymph node chain in stage I to III breast cancer (EORTC trial 22922/10925)

artículo científico publicado en 2010

Trial design on prophylaxis and treatment of brain metastases: lessons learned from the EORTC Brain Metastases Strategic Meeting 2012.

artículo científico publicado en 2012

Uptake of two 10B-compounds in liver metastases of colorectal adenocarcinoma for extracorporeal irradiation with boron neutron capture therapy (EORTC Trial 11001).

artículo científico publicado en 2008

Use of modern imaging methods to facilitate trials of metastasis-directed therapy for oligometastatic disease in prostate cancer: a consensus recommendation from the EORTC Imaging Group

artículo científico publicado en 2018

Using PSA to guide timing of androgen deprivation in patients with T0-4 N0-2 M0 prostate cancer not suitable for local curative treatment (EORTC 30891)

artículo científico publicado en 2007

Variability in the recurrence rate at first follow-up cystoscopy after TUR in stage Ta T1 transitional cell carcinoma of the bladder: a combined analysis of seven EORTC studies

artículo científico publicado en 2002

What can be concluded from the ERSPC and PLCO trial data? ⬇️

artículo científico publicado el 1 de noviembre de 2010

What has been learned from meta-analyses of neoadjuvant and adjuvant chemotherapy in bladder cancer?

artículo científico publicado en 2006

Whole body MRI in spondyloarthritis (SpA): Preliminary results suggest that DWI outperforms STIR for lesion detection

artículo científico publicado en 2018

Whole-breast irradiation with or without a boost for patients treated with breast-conserving surgery for early breast cancer: 20-year follow-up of a randomised phase 3 trial

artículo científico publicado en 2014

pT3N0M0 prostate cancer: a plea for adjuvant radiation

artículo científico publicado en 2009

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