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A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials

artículo científico publicado en 2019

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease

artículo científico publicado en 2020

Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later

artículo científico publicado en 2013

Amyloid β-associated cognitive decline in the absence of clinical disease progression and systemic illness

artículo científico publicado en 2017

Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease

scientific article published on 02 December 2019

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

scientific article published on 01 January 2020

BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease

artículo científico publicado en 2016

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease

artículo científico publicado en 2015

Cerebrospinal Fluid Biomarkers and Reserve Variables as Predictors of Future "Non-Cognitive" Outcomes of Alzheimer's Disease

scientific article published on 16 April 2016

Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning

artículo científico publicado en 2016

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease

artículo científico publicado en 2019

Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis

artículo científico publicado en 2016

Differentiating cognitive impairment due to corticobasal degeneration and Alzheimer disease

artículo científico publicado en 2017

Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease

scientific article published on 25 August 2018

Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network

scientific article published on 13 October 2018

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease

artículo científico publicado en 2019

Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease

scientific article published on 11 June 2018

Examining the Complicated Relationship Between Depressive Symptoms and Cognitive Impairment in Preclinical Alzheimer Disease

scientific article published on 01 January 2019

Functional connectivity and graph theory in preclinical Alzheimer's disease

scientific article published on 18 October 2013

In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging

artículo científico publicado en 2016

Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers

artículo científico publicado en 2018

Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease

scientific article published on 01 August 2018

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

artículo científico publicado en 2018

Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study

artículo científico publicado en 2016

Neurofilament Light Predicts Decline in Attention but Not Episodic Memory in Preclinical Alzheimer's Disease

artículo científico publicado en 2020

Neuropsychological measures that detect early impairment and decline in preclinical Alzheimer disease

artículo científico publicado en 2017

Physical Exercise and Longitudinal Trajectories in Alzheimer Disease Biomarkers and Cognitive Functioning

artículo científico publicado en 2020

Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study

artículo científico publicado en 2013

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning

scientific article published on 11 February 2020

Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults

artículo científico publicado en 2018

Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease

scientific article published on 23 June 2020

Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study

artículo científico publicado en 2020

Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease

scientific article published on 06 June 2020

Sex-specific genetic predictors of Alzheimer's disease biomarkers

artículo científico publicado en 2018

Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease

scholarly article by Guoqiao Wang et al published 2018 in Alzheimer's & dementia (New York, N. Y.)

Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease

scientific article published on 15 July 2020

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

artículo científico publicado en 2018

Spatially distinct atrophy is linked to β-amyloid and tau in preclinical Alzheimer disease

artículo científico publicado en 2015

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset

artículo científico publicado en 2019

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid β-Associated Cognitive Decline in Older Adults

artículo científico publicado en 2019

Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers

scientific article published on 01 April 2019

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

artículo científico publicado en 2016

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease

scientific article published on 21 March 2019

The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model

artículo científico publicado en 2016

Two-period linear mixed effects models to analyze clinical trials with run-in data when the primary outcome is continuous: Applications to Alzheimer's disease

scientific article published on 05 September 2019

Use of an experimental language acquisition paradigm for standardized neuropsychological assessment of learning: A pilot study in young and older adults

artículo científico publicado en 2019

Vascular risk factors are associated with longitudinal changes in cerebrospinal fluid tau markers and cognition in preclinical Alzheimer's disease

scientific article published on 01 August 2019

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

article by Miguel Ángel Araque Caballero et al published 1 October 2018 in Brain