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125I versus 103Pd for low-risk prostate cancer: preliminary PSA outcomes from a prospective randomized multicenter trial.

artículo científico publicado en 2003

20 Gy versus 44 Gy supplemental beam radiation with Pd-103 prostate brachytherapy: preliminary biochemical outcomes from a prospective randomized multi-center trial

scientific article published on 01 June 2005

A DNA methylation microarray-based study identifies ERG as a gene commonly methylated in prostate cancer

artículo científico publicado en 2011

A Novel System for Estimating Residual Disease and Pathologic Response to Neoadjuvant Treatment of Prostate Cancer

artículo científico publicado en 2016

A causal role for ERG in neoplastic transformation of prostate epithelium.

artículo científico publicado en 2008

A challenge for the diagnostic immunohistopathologist. Adding the CD phenotypes to our diagnostic toolbox

scientific article published on 01 July 2003

A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues

artículo científico publicado en 2022

A model for the design and construction of a resource for the validation of prognostic prostate cancer biomarkers: the Canary Prostate Cancer Tissue Microarray

artículo científico

A molecular correlate to the Gleason grading system for prostate adenocarcinoma

artículo científico publicado en 2006

A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer

artículo científico publicado en 2015

A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49

artículo científico publicado en 2002

Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors

artículo científico publicado en 2014

Active surveillance for prostate cancer: the role of the pathologist

article

Aggressive variants of castration-resistant prostate cancer

artículo científico publicado en 2014

An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones.

artículo científico publicado en 1998

Analysis and sorting of prostate cancer cell types by flow cytometry

artículo científico publicado en 1999

Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH.

artículo científico publicado en 2016

Analyzing patterns of staining in immunohistochemical studies: application to a study of prostate cancer recurrence

scientific article published on 01 May 2005

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

artículo científico publicado en 2017

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

scientific article published on July 2009

Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

artículo científico publicado en 2018

Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

artículo científico publicado en 2011

Application of Affymetrix array and Massively Parallel Signature Sequencing for identification of genes involved in prostate cancer progression

artículo científico publicado en 2005

Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer.

artículo científico publicado en 2017

Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy

scientific article published on 19 March 2019

Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2.

artículo científico publicado en 2016

Bladder expression of CD cell surface antigens and cell-type-specific transcriptomes.

artículo científico publicado en 2012

Bone histology at autopsy and matched bone scintigraphy findings in patients with hormone refractory prostate cancer: the effect of bisphosphonate therapy on bone scintigraphy results

artículo científico publicado el 1 de enero de 2003

Bone metastasis in prostate cancer: Recurring mitochondrial DNA mutation reveals selective pressure exerted by the bone microenvironment

artículo científico publicado en 2015

Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer

artículo científico publicado en 2018

CD90/THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker

artículo científico publicado en 2010

Cathepsin K mRNA and protein expression in prostate cancer progression

artículo científico publicado en 2003

Cell proliferation and apoptosis during prostatic tumor xenograft involution and regrowth after castration

scientific article published on 01 September 1996

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations

artículo científico publicado en 2016

Cell–cell interaction in prostate gene regulation and cytodifferentiation

artículo científico publicado el 30 de septiembre de 1997

Characterization of a novel androgen-sensitive, prostate-specific antigen-producing prostatic carcinoma xenograft: LuCaP 23.

artículo científico publicado en 1996

Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases

artículo científico publicado en 2013

Characterization of prostate cell types by CD cell surface molecules

artículo científico publicado en 2002

Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer

artículo científico publicado en 2016

Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes

artículo científico publicado en 2014

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study

artículo científico publicado en 2018

Clinical correlates to PSA spikes and positive repeat biopsies after prostate brachytherapy

artículo científico publicado el 1 de octubre de 2003

Comparative Effectiveness of a Patient Centered Pathology Report for Bladder Cancer Care

artículo científico publicado en 2016

Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer

artículo científico publicado en 2009

Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist

artículo científico publicado en 2014

Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

artículo científico publicado en 2018

Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate

artículo científico publicado en 2008

De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc

scientific article published on 02 October 2020

Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine

artículo científico publicado en 2011

Development of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE).

artículo científico publicado en 2006

Diagnosing 12 prostate needle cores within an hour of biopsy via open-top light-sheet microscopy

artículo científico publicado en 2020

Differences in Upgrading of Prostate Cancer in Prostatectomies between Community and Academic Practices

artículo científico publicado en 2013

Differential Inductive Signaling of CD90 Prostate Cancer-Associated Fibroblasts Compared to Normal Tissue Stromal Mesenchyme Cells.

artículo científico publicado en 2011

Differential expression of CD10 in prostate cancer and its clinical implication

artículo científico publicado en 2007

Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases

artículo científico

Differential expression of osteonectin/SPARC during human prostate cancer progression

artículo científico publicado en 2000

Differential gene expression in benign prostate epithelium of men with and without prostate cancer: evidence for a prostate cancer field effect

artículo científico publicado en 2010

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

artículo científico publicado en 2015

Effect of Preanalytic Variables on an Automated PTEN Immunohistochemistry Assay for Prostate Cancer

artículo científico publicado en 2018

Effects of androgen deprivation therapy and bisphosphonate treatment on bone in patients with metastatic castration-resistant prostate cancer: results from the University of Washington Rapid Autopsy Series

artículo científico publicado en 2013

Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases

artículo científico publicado en 2015

Evaluation of ERG and SPINK1 by Immunohistochemical Staining and Clinicopathological Outcomes in a Multi-Institutional Radical Prostatectomy Cohort of 1067 Patients.

artículo científico publicado en 2015

Expression of prostate specific membrane antigen and three alternatively spliced variants of PSMA in prostate cancer patients

artículo científico publicado en 2003

Expression of the human cachexia-associated protein (HCAP) in prostate cancer and in a prostate cancer animal model of cachexia

artículo científico publicado en 2003

Factors predictive of rectal bleeding after 103Pd and supplemental beam radiation for prostate cancer

artículo científico publicado en 2004

Flat Urothelial Lesions With Atypia: Interobserver Concordance and Added Value of Immunohistochemical Profiling.

artículo científico publicado en 2018

Gene expression down-regulation in CD90+ prostate tumor-associated stromal cells involves potential organ-specific genes

artículo científico publicado en 2009

Gene expression relationship between prostate cancer cells of Gleason 3, 4 and normal epithelial cells as revealed by cell type-specific transcriptomes

artículo científico publicado en 2009

Gene fusion analysis in renal cell carcinoma by FusionPlex RNA-sequencing and correlations of molecular findings with clinicopathological features

scientific article published on 10 August 2019

Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations

artículo científico publicado en 2019

Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer

scientific article published on 28 March 2019

Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients

artículo científico publicado en 2008

Harnessing non-destructive 3D pathology

scientific article published in 2021

Heterogeneity in primary and metastatic prostate cancer as defined by cell surface CD profile

artículo científico publicado en 2004

Hevin, an antiadhesive extracellular matrix protein, is down-regulated in metastatic prostate adenocarcinoma

artículo científico publicado en 1998

Histologic Grading of Prostatic Adenocarcinoma Can Be Further Optimized: Analysis of the Relative Prognostic Strength of Individual Architectural Patterns in 1275 Patients From the Canary Retrospective Cohort

artículo científico publicado en 2016

Histologic changes associated with neoadjuvant chemotherapy are predictive of nodal metastases in patients with high-risk prostate cancer.

artículo científico publicado en 2010

Histological, immunophenotypic and histomorphometric characterization of prostate cancer bone metastases

artículo científico publicado en 2004

Histopathological assessment of prostate cancer bone osteoblastic metastases

artículo científico publicado en 2008

How wide is the spectrum of neuroendocrine carcinoma of the urinary bladder?

artículo científico publicado en 2007

Human cancers express a mutator phenotype

artículo científico publicado en 2006

I-125 versus Pd-103 for low-risk prostate cancer: long-term morbidity outcomes from a prospective randomized multicenter controlled trial

artículo científico publicado en 2005

I-125 versus Pd-103 for low-risk prostate cancer: morbidity outcomes from a prospective randomized multicenter trial

artículo científico publicado en 2002

Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer

scientific article published on 05 December 2019

Identification of differentially expressed prostate genes: increased expression of transcription factor ETS-2 in prostate cancer

artículo científico

Immunohistochemical validation of expression microarray results

artículo científico publicado en 2005

Inhibition of angiopoietin-2 in LuCaP 23.1 prostate cancer tumors decreases tumor growth and viability

artículo científico publicado en 2010

Integrative Clinical Genomics of Advanced Prostate Cancer.

artículo científico publicado en 2015

Integrative clinical genomics of advanced prostate cancer

artículo científico publicado en 2015

Intense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study

artículo científico publicado en 2014

Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

artículo científico publicado en 2021

International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 1: specimen handling

artículo científico publicado el 10 de septiembre de 2010

Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists

artículo científico publicado en 2014

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

artículo científico publicado en 2007

Is partial cystectomy the treatment of choice for mucinous adenocarcinoma of the urachus?

artículo científico publicado en 1997

Isolation and characterization of human and mouse WDR19,a novel WD-repeat protein exhibiting androgen-regulated expression in prostate epithelium

artículo científico publicado en 2003

Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens

artículo científico publicado en 2017

Long-Term Outcomes for Patients with Prostate Cancer Having Intermediate and High-Risk Disease, Treated with Combination External Beam Irradiation and Brachytherapy

artículo científico publicado el 18 de agosto de 2010

Long-term outcomes after treatment with brachytherapy and supplemental conformal radiation for prostate cancer patients having intermediate and high-risk features

scientific article published on 01 August 2007

Long-term outcomes after treatment with external beam radiation therapy and palladium 103 for patients with higher risk prostate carcinoma: influence of prostatic acid phosphatase

artículo científico publicado en 2003

Long-term prostate cancer control using palladium-103 brachytherapy and external beam radiotherapy in patients with a high likelihood of extracapsular cancer extension

artículo científico publicado en 2007

Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort

artículo científico publicado en 2016

Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma

artículo científico publicado en 2005

LuCaP 35: A new model of prostate cancer progression to androgen independence

artículo científico publicado el 1 de junio de 2003

LuCaP Prostate Cancer Patient-Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease an--d Serve as Models for Evaluating Cancer Therapeutics.

artículo científico publicado en 2017

MUC1 Expression by Immunohistochemistry Is Associated with Adverse Pathologic Features in Prostate Cancer: A Multi-Institutional Study

artículo científico publicado en 2016

Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth

artículo científico publicado en 2008

Metastases of prostate cancer express estrogen receptor-beta

artículo científico publicado en 2004

Metastatic Adenocarcinoma of the Epididymis: A Case Report and Brief Literature Review

artículo científico publicado en 2017

Metastatic conventional prostatic adenocarcinoma with diffuse chromogranin A and androgen receptor positivity

artículo científico publicado en 2004

Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE)

artículo científico publicado en 2008

Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate

artículo científico

Mismatch repair enzyme expression in primary and castrate resistant prostate cancer.

artículo científico publicado en 2016

Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: identification of a cytoprotective mechanism involving growth differentiation factor 15.

artículo científico publicado en 2007

Molecular and cellular characterization of ABCG2 in the prostate

artículo científico publicado en 2007

Molecular characterization of prostatic small-cell neuroendocrine carcinoma

artículo científico publicado en 2003

Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer

artículo científico publicado en 2019

Morbidity effect of the time gap between supplemental beam radiation and Pd-103 prostate brachytherapy

artículo científico publicado en 2003

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

scientific article published on 04 July 2019

Multiplexed functional genomic analysis of 5' untranslated region mutations across the spectrum of prostate cancer

artículo científico publicado en 2021

Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease

artículo científico publicado en 2009

Open-Top Light-Sheet Microscopy Image Atlas of Prostate Core Needle Biopsies

scientific article published on 20 March 2019

Optimized prostate brachytherapy minimizes the prognostic impact of percent of biopsy cores involved with adenocarcinoma

artículo científico publicado en 2007

Osteoprotegerin and rank ligand expression in prostate cancer

artículo científico publicado en 2001

Outcomes of Active Surveillance for Clinically Localized Prostate Cancer in the Prospective, Multi-Institutional Canary PASS Cohort

artículo científico publicado en 2015

Overexpression of protease-activated receptors-1,-2, and-4 (PAR-1, -2, and -4) in prostate cancer

scholarly article by Peter C Black et al published 1 May 2007 in The Prostate

Oxidative DNA damage in the prostate may predispose men to a higher risk of prostate cancer

artículo científico publicado en 2009

PTEN Loss as Determined by Clinical-grade Immunohistochemistry Assay Is Associated with Worse Recurrence-free Survival in Prostate Cancer

artículo científico publicado en 2016

Pathology Imagebase-a reference image database for standardization of pathology.

artículo científico publicado en 2017

Persistent intraprostatic androgen concentrations after medical castration in healthy men.

artículo científico publicado en 2006

Phenotypic heterogeneity of end-stage prostate carcinoma metastatic to bone

artículo científico publicado en 2003

Placental bone morphogenetic protein (PLAB) gene expression in normal, pre-malignant and malignant human prostate: relation to tumor development and progression

artículo científico publicado en 2001

Positive surgical margins at radical prostatectomy predict prostate cancer specific mortality

artículo científico publicado en 2010

Practice patterns related to prostate cancer grading: results of a 2019 Genitourinary Pathology Society clinician survey

scientific article published on 15 September 2020

Prise en charge de la pièce de prostatectomie radicale. Résultats de la conférence de consensus de la Société internationale d’uropathologie (ISUP)

article by Eva Compérat et al published June 2013 in Annales de Pathologie

Prognostic value of Ki67 in localized prostate carcinoma: a multi-institutional study of >1000 prostatectomies

artículo científico publicado en 2016

Prostate cancer cell phenotypes based on AGR2 and CD10 expression

artículo científico publicado en 2013

Prostate cancer that is within 0.1 mm of the surgical margin of a radical prostatectomy predicts greater likelihood of recurrence

artículo científico publicado en 2014

Prostate cancer-associated gene expression alterations determined from needle biopsies

artículo científico publicado en 2009

Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

artículo científico publicado en 1999

Prostatic acid phosphatase adversely affects cause-specific survival in patients with intermediate to high-risk prostate cancer treated with brachytherapy

artículo científico publicado en 2008

Protease-activated receptor 2 signaling upregulates angiogenic growth factors in renal cell carcinoma

artículo científico publicado en 2012

Protease-activated receptor-1 is upregulated in reactive stroma of primary prostate cancer and bone metastasis

artículo científico publicado en 2009

Readability of urologic pathology reports: the need for patient-centered approaches.

artículo científico

Regulation of CEACAM5 and therapeutic efficacy of an anti-CEACAM5-SN38 antibody-drug conjugate in neuroendocrine prostate cancer

artículo científico publicado en 2020

Regulation of hepatocyte activator inhibitor-1 expression by androgen and oncogenic transformation in the prostate

artículo científico publicado en 2005

Renal Cell Carcinoma with Angioleiomyoma-Like Stroma and Clear Cell Papillary Renal Cell Carcinoma: Exploring SDHB Protein Immunohistochemistry and the Relationship to Tuberous Sclerosis Complex

artículo científico publicado en 2017

Renal cell carcinoma with angioleiomyoma-like stroma: clinicopathological, immunohistochemical, and molecular features supporting classification as a distinct entity

artículo científico publicado en 2014

Response to Neoadjuvant Chemotherapy and Survival in Micropapillary Urothelial Carcinoma: Data From a Tertiary Referral Center and the Surveillance, Epidemiology, and End Results (SEER) Program

artículo científico publicado en 2020

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

artículo científico publicado en 2015

Solid immersion meniscus lens (SIMlens) for open-top light-sheet microscopy

scientific article published on 01 September 2019

Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms

scientific article published on 11 April 2019

Sporadic Oncocytic Tumors with Features Intermediate between Oncocytoma and Chromophobe Renal Cell Carcinoma: Comprehensive Clinico-Pathological and Genomic Profiling

scientific article published on 13 July 2020

Stromal mesenchyme cell genes of the human prostate and bladder

artículo científico publicado en 2005

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

scientific article published on 29 February 2016

Surgical pathology and the patient: a systematic review evaluating the primary audience of pathology reports

artículo científico publicado en 2014

TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis

artículo científico publicado en 2017

Targeted androgen pathway suppression in localized prostate cancer: a pilot study

artículo científico publicado en 2013

Tertiary Gleason pattern 5 in Gleason 7 prostate cancer predicts pathological stage and biochemical recurrence

scientific article published on 17 March 2008

Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion

scientific article published on 02 August 2019

The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer

scientific article published on 26 June 2020

The accumulation of versican in the nodules of benign prostatic hyperplasia

artículo científico publicado en 2009

The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.

artículo científico publicado en 2014

The critical role of the pathologist in determining eligibility for active surveillance as a management option in patients with prostate cancer: consensus statement with recommendations supported by the College of American Pathologists, Internationa

artículo científico

The development and comparative effectiveness of a patient-centered prostate biopsy report: a prospective, randomized study

artículo científico publicado en 2019

The effect of supplemental beam radiation on prostate brachytherapy-related morbidity: morbidity outcomes from two prospective randomized multicenter trials

artículo científico publicado en 2003

The expression of osteoclastogenesis-associated factors and osteoblast response to osteolytic prostate cancer cells

artículo científico publicado en 2010

The landscape of somatic copy-number alteration across human cancers

artículo científico publicado en 2010

The potential impact of reproducibility of Gleason grading in men with early stage prostate cancer managed by active surveillance: a multi-institutional study

artículo científico publicado en 2011

The prognostic significance of Gleason pattern 5 in prostate cancer patients treated with Pd 103 plus beam radiation therapy

artículo científico publicado en 2004

The prognostic significance of Gleason pattern 5 in prostate cancer patients treated with Pd-103 brachytherapy

scientific article published on December 2007

The role of tissue microarrays in prostate cancer biomarker discovery

artículo científico publicado en 2007

The time gap between Pd-103 prostate brachytherapy and supplemental beam radiation does not impact on rectal morbidity or likelihood of cure

artículo científico publicado en 2008

The urologic epithelial stem cell database (UESC) - a web tool for cell type-specific gene expression and immunohistochemistry images of the prostate and bladder

artículo científico publicado en 2007

Transcriptomes of human prostate cells

artículo científico publicado en 2006

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

artículo científico publicado en 2012

Trends in Metastatic Kidney Cancer Survival From the Cytokine to the Targeted Therapy Era.

artículo científico publicado en 2015

Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor (IGF-IR) gene transcription in an androgen receptor-dependent manner

artículo científico publicado en 2009

Tumour cell survival mechanisms in lethal metastatic prostate cancer differ between bone and soft tissue metastases

artículo científico publicado en 2013

Urinary prostate specific antigen levels after radical prostatectomy

scientific article published on 01 January 1994

Utility of Pathology Imagebase for Standardization of Prostate Cancer Grading

artículo científico publicado en 2018

Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention

artículo científico publicado en 2010

WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence

artículo científico publicado en 2008