Lista de obras -

1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin.

artículo científico

A Comprehensive Guide to Sleeping Beauty-Based Somatic Transposon Mutagenesis in the Mouse

artículo científico publicado en 2011

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

artículo científico publicado en 2015

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

artículo científico publicado en 2015

A novel role for SALL4 during scar-free wound healing in axolotl.

artículo científico publicado en 2016

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

artículo científico publicado en 2017

CRISPR/Cas9 library screening for drug target discovery

artículo científico publicado en 2017

CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells

artículo científico publicado en 2020

Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance

artículo científico publicado en 2013

Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma.

artículo científico publicado en 2017

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.

artículo científico publicado en 2012

Coping with cancer genes altered by copy number

artículo científico publicado en 2015

EditR: A Method to Quantify Base Editing from Sanger Sequencing

scientific article published on 01 June 2018

Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells

artículo científico

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

scientific article published on 13 June 2019

Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease

artículo científico publicado en 2018

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

artículo científico publicado en 2013

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

artículo científico publicado en 2018

HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs

artículo científico publicado en 2014

Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas

artículo científico publicado en 2019

Implication of ZNF217 in accelerating tumor development and therapeutically targeting ZNF217-induced PI3K-AKT signaling for the treatment of metastatic osteosarcoma

artículo científico publicado en 2020

Modular assembly of transposon integratable multigene vectors using RecWay assembly.

artículo científico publicado en 2013

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

artículo científico publicado en 2016

PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma

artículo científico publicado en 2020

PM-05ARHGAP36 AS A NOVEL DRIVER IN HIGH-RISK HUMAN MEDULLOBLASTOMA.

artículo científico publicado en 2014

PTPS-02FOXR2: AN ONCOGENE IN MEDULLOBLASTOMA.

artículo científico publicado en 2015

PVT1 dependence in cancer with MYC copy-number increase.

artículo científico

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

artículo científico publicado en 2016

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

artículo científico publicado en 2017

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

artículo científico publicado en 2016

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

artículo científico publicado en 2015

Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

artículo científico publicado en 2017

Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts

scientific article published on 11 January 2017

SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

artículo científico publicado en 2012

Simple and efficient methods for enrichment and isolation of endonuclease modified cells

artículo científico publicado en 2014

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma

artículo científico publicado en 2018

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery

artículo científico

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma.

artículo científico publicado en 2016

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

artículo científico publicado en 2015

The Molecular Imaging of Natural Killer Cells

scholarly article published in Molecular imaging : official journal of the Society for Molecular Imaging

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

artículo científico publicado en 2016

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.

artículo científico publicado en 2015

Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis

artículo científico publicado en 2014

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

artículo científico publicado en 2014

Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML

artículo científico publicado en 2016

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress

artículo científico publicado en 2016

microRNA-based attenuation of influenza virus across susceptible hosts

artículo científico publicado en 2017

Lista de obras de

1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin.

A Comprehensive Guide to Sleeping Beauty-Based Somatic Transposon Mutagenesis in the Mouse

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

A novel role for SALL4 during scar-free wound healing in axolotl.

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

CRISPR/Cas9 library screening for drug target discovery

CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells

Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance

Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma.

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.

Coping with cancer genes altered by copy number

EditR: A Method to Quantify Base Editing from Sanger Sequencing

Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs

Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas

Implication of ZNF217 in accelerating tumor development and therapeutically targeting ZNF217-induced PI3K-AKT signaling for the treatment of metastatic osteosarcoma

Modular assembly of transposon integratable multigene vectors using RecWay assembly.

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma

PM-05ARHGAP36 AS A NOVEL DRIVER IN HIGH-RISK HUMAN MEDULLOBLASTOMA.

PTPS-02FOXR2: AN ONCOGENE IN MEDULLOBLASTOMA.

PVT1 dependence in cancer with MYC copy-number increase.

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts

SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

Simple and efficient methods for enrichment and isolation of endonuclease modified cells

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma.

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

The Molecular Imaging of Natural Killer Cells

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.

Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress

microRNA-based attenuation of influenza virus across susceptible hosts