Lista de obras -

A transposon and transposase system for human application

artículo científico publicado en 2010

Awakening gene therapy with Sleeping Beauty transposons

artículo científico publicado en 2005

Characterization of the Human Artemis Promoter by Heterologous Gene Expression In Vitro and In Vivo ⬇️

artículo científico publicado el 10 de junio de 2011

Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

artículo científico publicado en 2009

Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon

artículo científico publicado en 2006

Counterselection and co-delivery of transposon and transposase functions for Sleeping Beauty-mediated transposition in cultured mammalian cells

artículo científico publicado en 2004

DDE transposases: Structural similarity and diversity

artículo científico publicado en 2010

Delivering the second revolution in site-specific nucleases

artículo científico publicado en 2014

Duration of expression and activity of Sleeping Beauty transposase in mouse liver following hydrodynamic DNA delivery

artículo científico publicado en 2010

Editing livestock genomes with site-specific nucleases

artículo científico publicado en 2013

Effective Expression-Independent Gene Trapping and Mutagenesis Mediated by Sleeping Beauty Transposon ⬇️

artículo científico publicado el 23 de agosto de 2012

Effective Gene Trapping Mediated by Sleeping Beauty Transposon ⬇️

artículo científico publicado el 31 de agosto de 2012

Efficacy and Safety of Sleeping Beauty Transposon-Mediated Gene Transfer in Preclinical Animal Studies ⬇️

artículo científico publicado el 1 de octubre de 2011

Efficient nonmeiotic allele introgression in livestock using custom endonucleases ⬇️

artículo científico publicado el 6 de septiembre de 2013

Engineered Swine Models of Cancer

artículo científico publicado en 2016

Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy ⬇️

artículo científico publicado el 10 de enero de 2013

Fishing for answers with transposons.

artículo científico publicado en 2005

Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons

artículo científico publicado en 2010

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

artículo científico publicado en 2003

Gene therapy for neurologic manifestations of mucopolysaccharidoses

artículo científico publicado en 2014

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

artículo científico publicado en 2003

Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

artículo científico publicado en 2006

Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells.

artículo científico publicado en 2011

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.

artículo científico publicado en 2012

Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier

artículo científico publicado en 2014

Mammalian germ-line transgenesis by transposition.

artículo científico publicado en 2002

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

artículo científico publicado en 2010

NMR structural analysis ofSleeping Beautytransposase binding to DNA

artículo científico publicado en 2014

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

artículo científico publicado en 2016

Precision Editing of Large Animal Genomes ⬇️

artículo científico publicado el 1 de enero de 2012

Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy

artículo científico publicado en 2007

Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

artículo científico publicado en 2007

Prolonged Expression of Secreted Enzymes in Dogs After Liver-Directed Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Systemic Disease

artículo científico publicado en 2017

Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses

artículo científico publicado en 2007

Quantitative analysis of α-L-iduronidase expression in immunocompetent mice treated with the Sleeping Beauty transposon system

artículo científico publicado en 2013

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

artículo científico publicado en 2008

Sleeping Beauty System to Redirect T-cell Specificity for Human Applications ⬇️

artículo científico publicado el 1 de febrero de 2013

Sleeping Beauty-mediated correction of Fanconi anemia type C.

artículo científico publicado en 2011

Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression

artículo científico publicado en 2005

Sleeping beauty transposon-mediated gene therapy for prolonged expression

artículo científico publicado en 2005

Structure-based prediction of insertion-site preferences of transposons into chromosomes

artículo científico publicado en 2006

Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon

artículo científico publicado en 2002

Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system

artículo científico publicado en 2009

Targeting DNA With Fingers and TALENs ⬇️

artículo científico publicado el 24 de enero de 2012

The Sleeping Beauty transposon system: a non-viral vector for gene therapy ⬇️

artículo científico publicado el 15 de abril de 2011

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

artículo científico publicado en 2008

Translating Sleeping Beauty transposition into cellular therapies: victories and challenges

artículo científico publicado en 2010

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

artículo científico publicado en 2015

Lista de obras de

A transposon and transposase system for human application

Awakening gene therapy with Sleeping Beauty transposons

Characterization of the Human Artemis Promoter by Heterologous Gene Expression In Vitro and In Vivo ⬇️

Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon

Counterselection and co-delivery of transposon and transposase functions for Sleeping Beauty-mediated transposition in cultured mammalian cells

DDE transposases: Structural similarity and diversity

Delivering the second revolution in site-specific nucleases

Duration of expression and activity of Sleeping Beauty transposase in mouse liver following hydrodynamic DNA delivery

Editing livestock genomes with site-specific nucleases

Effective Expression-Independent Gene Trapping and Mutagenesis Mediated by Sleeping Beauty Transposon ⬇️

Effective Gene Trapping Mediated by Sleeping Beauty Transposon ⬇️

Efficacy and Safety of Sleeping Beauty Transposon-Mediated Gene Transfer in Preclinical Animal Studies ⬇️

Efficient nonmeiotic allele introgression in livestock using custom endonucleases ⬇️

Engineered Swine Models of Cancer

Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy ⬇️

Fishing for answers with transposons.

Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

Gene therapy for neurologic manifestations of mucopolysaccharidoses

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells.

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.

Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier

Mammalian germ-line transgenesis by transposition.

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

NMR structural analysis ofSleeping Beautytransposase binding to DNA

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Precision Editing of Large Animal Genomes ⬇️

Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy

Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

Prolonged Expression of Secreted Enzymes in Dogs After Liver-Directed Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Systemic Disease

Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses

Quantitative analysis of α-L-iduronidase expression in immunocompetent mice treated with the Sleeping Beauty transposon system

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

Sleeping Beauty System to Redirect T-cell Specificity for Human Applications ⬇️

Sleeping Beauty-mediated correction of Fanconi anemia type C.

Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression

Sleeping beauty transposon-mediated gene therapy for prolonged expression

Structure-based prediction of insertion-site preferences of transposons into chromosomes

Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon

Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system

Targeting DNA With Fingers and TALENs ⬇️

The Sleeping Beauty transposon system: a non-viral vector for gene therapy ⬇️

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

Translating Sleeping Beauty transposition into cellular therapies: victories and challenges

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery