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A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

artículo científico

A solvent resistant lab-on-chip platform for radiochemistry applications

artículo científico publicado en 2014

Anticalins directed against the fibronectin extra domain B as diagnostic tracers for glioblastomas

artículo científico publicado en 2015

Asymmetry of fibrillar plaque burden in amyloid mouse models

scientific article published on 15 May 2020

Automated production of [18F]SiTATE on a Scintomics GRP™ platform for PET/CT imaging of neuroendocrine tumors

scientific article published on 30 July 2020

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

artículo científico publicado en 2018

Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification

artículo científico publicado en 2017

Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium

artículo científico publicado en 2018

Detection of Cerebrospinal Fluid Dissemination of Recurrent Glioblastoma Using TSPO-PET With 18F-GE-180.

artículo científico publicado en 2018

Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice

scientific article published on 27 September 2018

First-in-Human Brain Imaging of [18F]TRACK, a PET tracer for Tropomyosin Receptor Kinases

scientific article published on 29 April 2019

Fully Automated Production and Characterization of 64 Cu and Proof-of-Principle Small-Animal PET Imaging Using 64 Cu-Labelled CA XII Targeting 6A10 Fab.

artículo científico publicado en 2018

Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study

artículo científico publicado en 2016

Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases

artículo científico publicado en 2020

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

artículo científico publicado en 2017

Imaging microglial activation in tacrolimus-associated CNS vasculitis with translocator protein PET

scientific article published on 01 November 2018

In Vivo Imaging of Glial Activation after Unilateral Labyrinthectomy in the Rat: A [18F]GE180-PET Study

artículo científico publicado en 2017

Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

artículo científico publicado en 2017

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model

artículo científico publicado en 2019

Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning

artículo científico publicado en 2020

Microfluidics: a groundbreaking technology for PET tracer production?

artículo científico publicado en 2013

Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in App<sup>NL-G-F</sup> mice

artículo científico publicado en 2020

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study

Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel 68Ga-mCXCL12 PET tracer

artículo científico publicado en 2020

Perfusion-Phase [18F]THK5351 Tau-PET Imaging as a Surrogate Marker for Neurodegeneration

scientific article published on 28 September 2017

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

artículo científico publicado en 2019

Small-Animal PET Imaging of Tau Pathology with 18F-THK5117 in 2 Transgenic Mouse Models

artículo científico publicado en 2016

Synthesis and in vitro and in vivo evaluation of SiFA-tagged bombesin and RGD peptides as tumor imaging probes for positron emission tomography

artículo científico publicado en 2014

TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis

artículo científico publicado en 2017

Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study

artículo científico publicado en 2017

[18F]-THK5351 PET Correlates with Topology and Symptom Severity in Progressive Supranuclear Palsy.

artículo científico publicado en 2017

[18F]MPPF and [18F]FDG μPET imaging in rats: impact of transport and restraint stress

scientific article published on 29 September 2020