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Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice

B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis

artículo científico publicado en 2011

B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis.

artículo científico publicado en 2008

B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice

artículo científico publicado en 2009

Biochemical and immunologic effects of rituximab in patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid

artículo científico publicado en 2012

Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII mice

artículo científico publicado en 2013

DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

artículo científico publicado en 2015

Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis

artículo científico publicado en 2009

Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice

artículo científico publicado en 2013

Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice

artículo científico publicado en 2009

Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis

artículo científico publicado en 2010

Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice

artículo científico publicado en 2009

Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα(-/-) mice

artículo científico publicado en 2014

Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis

artículo científico publicado en 2011

Gut microbiota translocation promotes autoimmune cholangitis

artículo científico publicado en 2018

Lymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGFβ receptor II.

artículo científico publicado en 2012

Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production

scientific article published on 15 August 2009

Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse

artículo científico publicado en 2013

Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells

artículo científico publicado en 2014

The fingerprint of antimitochondrial antibodies and the etiology of primary biliary cholangitis

artículo científico publicado en 2017

The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice

artículo científico publicado en 2012

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