Lista de obras -

A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6.

artículo científico publicado en 2016

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

artículo científico publicado en 1996

A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo.

artículo científico publicado en 2004

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

artículo científico publicado en 1998

A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene

artículo científico publicado en 2002

Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene

scientific article published on 01 July 1993

Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements

artículo científico publicado en 2003

Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice

artículo científico publicado en 1993

Attenuation of fibrosis in vitro and in vivo with SPARC siRNA

artículo científico publicado en 2010

Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes ⬇️

artículo científico publicado el 15 de septiembre de 1993

Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice

artículo científico publicado en 1994

Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification ⬇️

artículo científico publicado el 21 de enero de 2012

Chondrocytes transdifferentiate into osteoblasts in endochondral bone during development, postnatal growth and fracture healing in mice

artículo científico publicado en 2014

Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain

artículo científico publicado en 1992

Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor

artículo científico publicado en 1996

Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes

scientific journal article

Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1).

artículo científico publicado en 1995

Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype

artículo científico publicado en 2004

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation

artículo científico publicado en 2005

Coordinate patterns of expression of type I and III collagens during mouse development

artículo científico publicado en 1995

Correction: SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters.

artículo científico publicado en 2015

Cthrc1 is a positive regulator of osteoblastic bone formation

scientific journal article

Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure

artículo científico publicado en 2009

Developmental expression of a type II collagen/beta-galactosidase fusion gene in transgenic mice

artículo científico publicado en 1995

E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein

artículo científico publicado en 2013

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

scientific journal article

Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumors

artículo científico publicado en 2010

Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family

artículo científico publicado en 2001

Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage

scientific article published on December 2009

Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization

scientific journal article

Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix

artículo científico publicado en 2013

Identification of SOX9 interaction sites in the genome of chondrocytes

artículo científico publicado en 2010

Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9.

artículo científico publicado en 2006

Interactions between Sox9 and beta-catenin control chondrocyte differentiation

artículo científico publicado en 2004

Joint formation requires muscle formation and contraction

artículo científico publicado en 2009

Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis

artículo científico publicado en 2002

Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation

artículo científico publicado en 2015

Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation

artículo científico publicado en 2015

Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing

artículo científico publicado en 1991

Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice

artículo científico publicado en 2010

NFAT and Osterix cooperatively regulate bone formation

artículo científico publicado en 2005

Normal long bone growth and development in type X collagen-null mice

artículo científico publicado en 1994

Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors

artículo científico publicado en 2005

Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene

artículo científico publicado en 2000

Osterix is required for cranial neural crest-derived craniofacial bone formation

artículo científico publicado en 2013

Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma

artículo científico publicado en 2005

Persistent low level of osterix accelerates interleukin-6 production and impairs regeneration after tissue injury

artículo científico publicado en 2013

Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer

artículo científico publicado en 2000

Positive regulation of adult bone formation by osteoblast-specific transcription factor osterix

artículo científico publicado en 2009

Postnatally induced inactivation of Osterix in osteoblasts results in the reduction of bone formation and maintenance

artículo científico publicado en 2009

Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene

artículo científico publicado en 1996

Purification and molecular cloning of the "A" chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor

scientific journal article

Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3

scientific journal article

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

scientific journal article

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

artículo científico publicado en 2010

SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc.

artículo científico publicado en 2016

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

scientific journal article

SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters

artículo científico publicado en 2014

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

artículo científico publicado en 2010

Sox9 is required for cartilage formation

scientific journal article

Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest

artículo científico publicado en 2003

Sp7 and Runx2 molecular complex synergistically regulate expression of target genes

artículo científico publicado en 2014

Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter

artículo científico publicado en 2008

Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs.

artículo científico publicado en 1992

Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs

artículo científico publicado en 1991

Specificity protein 7 is not essential for tooth morphogenesis.

artículo científico publicado en 2014

Structural insights into histone demethylase NO66 in interaction with osteoblast-specific transcription factor osterix and gene repression

artículo científico publicado en 2013

TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation

artículo científico publicado en 1993

Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation

scientific journal article

The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor

artículo científico publicado en 1990

The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones

scientific journal article

The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template

artículo científico publicado en 2010

The exon structure of the mouse alpha 2(IX) collagen gene shows unexpected divergence from the chick gene

artículo científico publicado en 1994

The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern

artículo científico publicado en 1993

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

artículo científico publicado en 2002

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

scientific journal article

Toward understanding S0X9 function in chondrocyte differentiation ⬇️

artículo científico publicado el 1 de marzo de 1998

Transcriptional control mechanisms for the expression of type I collagen genes ⬇️

artículo científico publicado el 1 de noviembre de 1991

Transcriptional regulation of Vascular Endothelial Growth Factor (VEGF) by osteoblast-specific transcription factor Osterix (Osx) in osteoblasts

artículo científico publicado en 2011

Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5.

artículo científico publicado en 2008

Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth

artículo científico publicado en 2004

Transgenic mice with deficiencies in cartilage collagens: possible models for gene therapy.

artículo científico publicado en 1995

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

scientific journal article

p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

artículo científico publicado en 2005

Lista de obras de

A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6.

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo.

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene

Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene

Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements

Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice

Attenuation of fibrosis in vitro and in vivo with SPARC siRNA

Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes ⬇️

Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice

Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification ⬇️

Chondrocytes transdifferentiate into osteoblasts in endochondral bone during development, postnatal growth and fracture healing in mice

Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain

Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor

Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes

Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1).

Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation

Coordinate patterns of expression of type I and III collagens during mouse development

Correction: SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters.

Cthrc1 is a positive regulator of osteoblastic bone formation

Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure

Developmental expression of a type II collagen/beta-galactosidase fusion gene in transgenic mice

E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumors

Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family

Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage

Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization

Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix

Identification of SOX9 interaction sites in the genome of chondrocytes

Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9.

Interactions between Sox9 and beta-catenin control chondrocyte differentiation

Joint formation requires muscle formation and contraction

Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis

Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation

Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation

Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing

Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice

NFAT and Osterix cooperatively regulate bone formation

Normal long bone growth and development in type X collagen-null mice

Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors

Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene

Osterix is required for cranial neural crest-derived craniofacial bone formation

Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma

Persistent low level of osterix accelerates interleukin-6 production and impairs regeneration after tissue injury

Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer

Positive regulation of adult bone formation by osteoblast-specific transcription factor osterix

Postnatally induced inactivation of Osterix in osteoblasts results in the reduction of bone formation and maintenance

Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene

Purification and molecular cloning of the "A" chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor

Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc.

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

Sox9 is required for cartilage formation

Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest

Sp7 and Runx2 molecular complex synergistically regulate expression of target genes

Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter

Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs.

Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs

Specificity protein 7 is not essential for tooth morphogenesis.

Structural insights into histone demethylase NO66 in interaction with osteoblast-specific transcription factor osterix and gene repression

TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation

Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation

The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor

The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones

The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template

The exon structure of the mouse alpha 2(IX) collagen gene shows unexpected divergence from the chick gene

The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

Toward understanding S0X9 function in chondrocyte differentiation ⬇️

Transcriptional control mechanisms for the expression of type I collagen genes ⬇️

Transcriptional regulation of Vascular Endothelial Growth Factor (VEGF) by osteoblast-specific transcription factor Osterix (Osx) in osteoblasts