Lista de obras -

2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: Synthesis, in vitro cytotoxic activity, and QSAR investigations

artículo científico publicado en 2006

Analogues of Cis- and Transplatin with a Rich Solution Chemistry: cis-[PtCl2 (NH3 )(1-MeC-N3)] and trans-[PtI2 (NH3 )(1-MeC-N3)].

artículo científico publicado en 2015

Anticancer activity and mode of action of titanocene C.

artículo científico publicado en 2010

Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents

artículo científico publicado en 2008

Assessment of cisplatin concentration and depth of penetration in human lung tissue after hyperthermic exposure

artículo científico publicado en 2014

Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents

artículo científico publicado en 2009

Characterization of three B-cell lymphoma cell lines from chemotherapy resistant patients with respect to in vitro sensitivity to 21 antitumor agents, ABC-transporter expression and cellular redox status

artículo científico publicado en 2007

ChemInform Abstract: β-Lactam Derivatives as Potential Anticancer Compounds.

artículo científico publicado en 2008

Chiral platinum(II) metallointercalators with potent in vitro cytotoxic activity

artículo científico publicado en 2007

Comparison of Cellular Death Pathways after mTHPC-mediated Photodynamic Therapy (PDT) in Five Human Cancer Cell Lines

artículo científico publicado en 2019

Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data

artículo científico publicado en 2006

Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data

artículo científico publicado en 2007

Cytotoxic and antimicrobial activities of Cu(II), Co(II), Pt(II) and Zn(II) Complexes with N,O-chelating heterocyclic carboxylates

artículo científico publicado en 2011

Degradation and intermediates of diclofenac as instructive example for decomposition of recalcitrant pharmaceuticals by hydroxyl radicals generated with pulsed corona plasma in water

artículo científico publicado en 2017

EXAFS, DFT, Light-Induced Nucleobase Binding, and Cytotoxicity of the Photoactive Complexcis-[Ru(bpy)2(CO)Cl]+

Effects of cytotoxic cis- and trans-diammine monochlorido platinum(II) complexes on selenium-dependent redox enzymes and DNA.

artículo científico publicado en 2017

Electron-Transfer-Driven Trans-Ligand Labilization: A Novel Activation Mechanism for Pt(IV) Anticancer Complexes

artículo científico publicado en 1998

Evaluation for Synergistic Effects by Combinations of Photodynamic Therapy (PDT) with Temoporfin (mTHPC) and Pt(II) Complexes Carboplatin, Cisplatin or Oxaliplatin in a Set of Five Human Cancer Cell Lines

artículo científico publicado en 2018

Evaluation of (S)- and (R)-misonidazole as GPX inhibitors: synthesis, characterization including circular dichroism and in vitro testing on bovine GPx-1.

artículo científico publicado en 2013

First- and Second-Generation Heterometallic Dendrimers Containing Ferrocenyl–Ruthenium(II)–Arene Motifs: Synthesis, Structure, Electrochemistry, and Preliminary Cell Proliferation Studies

article by Preshendren Govender et al published 17 September 2014 in Organometallics

Flupirtine Analogues: Explorative Synthesis and Influence of Chemical Structure on K7.2/K7.3 Channel Opening Activity

Flupirtine and retigabine as templates for ligand-based drug design of KV7.2/3 activators

scientific article published on 01 May 2019

Gold(III) complexes with hydroxyquinoline, aminoquinoline and quinoline ligands: Synthesis, cytotoxicity, DNA and protein binding studies.

artículo científico publicado en 2015

Hybrid Molecules Composed of 2,4-Diamino-1,3,5-triazines and 2-Imino-Coumarins and Coumarins. Synthesis and Cytotoxic Properties

artículo científico publicado en 2018

Identification of a glutathione peroxidase inhibitor that reverses resistance to anticancer drugs in human B-cell lymphoma cell lines

artículo científico publicado en 2012

In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent

artículo científico publicado en 2009

In vitro anticancer activity and evaluation of DNA duplex binding affinity of phenyl-substituted indoloquinolines ⬇️

artículo científico publicado el 26 de febrero de 2011

In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(ii) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

artículo científico publicado en 2018

Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light

artículo científico publicado en 2015

Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors.

artículo científico publicado en 2012

Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)] ⬇️

artículo científico publicado el 21 de enero de 2011

Investigation of the in vitro metabolism of the analgesic flupirtine

artículo científico publicado en 2008

Light-activated destruction of cancer cell nuclei by platinum diazide complexes

artículo científico publicado en 2006

Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.

artículo científico publicado en 2015

Microwave-assisted synthesis and evaluation of acylhydrazones as potential inhibitors of bovine glutathione peroxidase

artículo científico publicado en 2014

Nicotinamide adenine dinucleotide phosphate-regenerating system coupled to a glutathione-reductase microtiter method for determination of total glutathione concentrations in adherent growing cancer cell lines

artículo científico publicado en 2003

No correlation between GSH levels in human cancer cell lines and the cell growth inhibitory activities of platinum diamine complexes.

artículo científico publicado en 2004

Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure-Activity Relationship Study

artículo científico publicado en 2015

Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines

artículo científico publicado en 2012

Nucleotide Platination Induced by Visible Light

artículo científico publicado en 1999

Oxidation potentials of N-modified derivatives of the analgesic flupirtine linked to potassium KV 7 channel opening activity but not hepatocyte toxicity.

artículo científico publicado en 2014

Pentathiepins: a novel class of glutathione peroxidase 1 inhibitors that induce oxidative stress, loss of mitochondrial membrane potential and apoptosis in human cancer cells

scientific article published on 20 April 2020

Pharmacological Evaluation of the Anticancer Activity of Extracts and Fractions of Lannea barteri Oliv. (Anacardiaceae) on Adherent Human Cancer Cell Lines

artículo científico publicado en 2020

Photoactivatable platinum complexes

artículo científico publicado en 2007

Photoactivation of Diiodido-Pt(IV) Complexes Coupled to Upconverting Nanoparticles

artículo científico publicado en 2016

Photosensitizers for Photodynamic Therapy: Photochemistry in the Service of Oncology

artículo científico publicado en 2016

Quantification of elastase-like activity in 13 human cancer cell lines and in an immortalized human epithelial cell line by RP-HPLC.

artículo científico publicado en 2003

Quantitative LC-MS/MS determination of flupirtine, its N-acetylated and two mercapturic acid derivatives in man

artículo científico publicado en 2014

Structural diversity of copper(II) complexes with N-(2-pyridyl)imidazolidin-2-ones(thiones) and their in vitro antitumor activity.

artículo científico publicado en 2014

Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.

artículo científico publicado en 2007

Structure-activity relationships of targeted RuII(η6-p-cymene) anticancer complexes with flavonol-derived ligands

artículo científico publicado en 2012

Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra

artículo científico publicado en 2009

Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.

artículo científico publicado en 2009

Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(iv) complexes ⬇️

artículo científico publicado el 4 de abril de 2011

Sulfide Analogues of Flupirtine and Retigabine with Nanomolar KV 7.2/KV 7.3 Channel Opening Activity

artículo científico publicado en 2019

Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines.

artículo científico publicado en 2012

Synthesis and Preliminary Cytotoxicity Studies of 1-[1-(4,5-Dihydrooxazol-2-yl)-1H-indazol-3-yl]-3-phenylurea and 3-phenylthiourea Derivatives

artículo científico publicado en 2017

Synthesis and anticancer activity of novel 2-amino-4-(4-phenylpiperazino)- 1,3,5-triazine derivatives.

artículo científico publicado en 2004

Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines.

artículo científico publicado en 2006

Synthesis and biological activity of some 2-imidazolinylhydrazone derivatives.

artículo científico publicado en 2009

Synthesis and cytotoxic activity of imidazo[1,2-a]-1,3,5-triazine analogues of 6-mercaptopurine

artículo científico publicado en 2008

Synthesis and cytotoxicity testing of novel 2-(3-substituted-6-chloro-1,1-dioxo-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinones

artículo científico publicado en 2008

Synthesis and in vitro anti-tumor activity of N-{1-[(3-thioxo-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene}arylsulfonamides

artículo científico publicado en 2006

Synthesis and potassium K7 channel opening activity of thioether analogues of the analgesic flupirtine

scientific article published on 01 November 2018

Synthesis of N-(2-pyridyl)imidazolidin-2-ones and 1-(2-pyridyl)-2,3,7,8-tetrahydro-1H-imidazo[2,1-b][1,3,5]triazepin-5(6H)-ones with potential biological activities

Synthesis of aza-aromatic hydroxylamine-O-sulfonates and their application to tandem nucleophilic addition–electrophilic 5-endo-trig cyclization

article

Synthesis of indirubin-N'-glycosides and their anti-proliferative activity against human cancer cell lines.

artículo científico publicado en 2008

Synthesis of novel aryl(heteroaryl)sulfonyl ureas of possible biological interest

artículo científico publicado en 2010

Synthesis, Structure and Cytotoxicity Testing of Novel 7-(4,5-dihydro-1H-imidazol-2-yl)-2-aryl-6,7-dihydro-2H-imidazo[2,1-c][1,2,4]triazol-3(5H)-Imine Derivatives

artículo científico publicado en 2020

Synthesis, Structure, Chemical Stability, and In Vitro Cytotoxic Properties of Novel Quinoline-3-Carbaldehyde Hydrazones Bearing a 1,2,4-Triazole or Benzotriazole Moiety

artículo científico publicado en 2018

Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles

artículo científico publicado en 2004

Synthesis, crystal structure and biological activities of copper(II) complexes with chelating bidentate 2-substituted benzimidazole ligands

artículo científico publicado en 2006

Synthesis, crystal structure, cytotoxic and superoxide dismutase activities of copper(II) complexes of N-(4,5-dihydroimidazol-2-yl)azoles

artículo científico publicado en 2007

Synthesis, cytotoxicity testing, and structure-activity relationships of novel 6-chloro-7-(4-phenylimino-4H-3,1-benzoxazin-2-yl)-3-(substituted)-1,4,2-benzodithiazine 1,1-dioxides

artículo científico publicado en 2011

Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates

artículo científico publicado en 2010

Synthesis, reactions and structure-activity relationships of 1-hydroxyspiro[2.5]cyclooct-4-en-3-ones: illudin analogs with in vitro cytotoxic activity

scientific article published on 17 April 2006

Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides

artículo científico publicado en 2007

The Effect of Glutathione Peroxidase-1 Knockout on Anticancer Drug Sensitivities and Reactive Oxygen Species in Haploid HAP-1 Cells

scientific article published on 18 December 2020

Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism.

artículo científico publicado en 2012

Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity

artículo científico publicado en 2009

Unusual reactivity of cytotoxic cis-dihydrazide Pt(II) complexes in aqueous solution

artículo científico publicado en 2003

[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis

artículo científico publicado en 2007

β-Lactam derivatives as potential anti-cancer compounds

artículo científico publicado en 2008

Lista de obras de

2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: Synthesis, in vitro cytotoxic activity, and QSAR investigations

Analogues of Cis- and Transplatin with a Rich Solution Chemistry: cis-[PtCl2 (NH3 )(1-MeC-N3)] and trans-[PtI2 (NH3 )(1-MeC-N3)].

Anticancer activity and mode of action of titanocene C.

Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents

Assessment of cisplatin concentration and depth of penetration in human lung tissue after hyperthermic exposure

Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents

Characterization of three B-cell lymphoma cell lines from chemotherapy resistant patients with respect to in vitro sensitivity to 21 antitumor agents, ABC-transporter expression and cellular redox status

ChemInform Abstract: β-Lactam Derivatives as Potential Anticancer Compounds.

Chiral platinum(II) metallointercalators with potent in vitro cytotoxic activity

Comparison of Cellular Death Pathways after mTHPC-mediated Photodynamic Therapy (PDT) in Five Human Cancer Cell Lines

Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data

Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data

Cytotoxic and antimicrobial activities of Cu(II), Co(II), Pt(II) and Zn(II) Complexes with N,O-chelating heterocyclic carboxylates

Degradation and intermediates of diclofenac as instructive example for decomposition of recalcitrant pharmaceuticals by hydroxyl radicals generated with pulsed corona plasma in water

EXAFS, DFT, Light-Induced Nucleobase Binding, and Cytotoxicity of the Photoactive Complexcis-[Ru(bpy)2(CO)Cl]+

Effects of cytotoxic cis- and trans-diammine monochlorido platinum(II) complexes on selenium-dependent redox enzymes and DNA.

Electron-Transfer-Driven Trans-Ligand Labilization: A Novel Activation Mechanism for Pt(IV) Anticancer Complexes

Evaluation for Synergistic Effects by Combinations of Photodynamic Therapy (PDT) with Temoporfin (mTHPC) and Pt(II) Complexes Carboplatin, Cisplatin or Oxaliplatin in a Set of Five Human Cancer Cell Lines

Evaluation of (S)- and (R)-misonidazole as GPX inhibitors: synthesis, characterization including circular dichroism and in vitro testing on bovine GPx-1.

First- and Second-Generation Heterometallic Dendrimers Containing Ferrocenyl–Ruthenium(II)–Arene Motifs: Synthesis, Structure, Electrochemistry, and Preliminary Cell Proliferation Studies

Flupirtine Analogues: Explorative Synthesis and Influence of Chemical Structure on K7.2/K7.3 Channel Opening Activity

Flupirtine and retigabine as templates for ligand-based drug design of KV7.2/3 activators

Gold(III) complexes with hydroxyquinoline, aminoquinoline and quinoline ligands: Synthesis, cytotoxicity, DNA and protein binding studies.

Hybrid Molecules Composed of 2,4-Diamino-1,3,5-triazines and 2-Imino-Coumarins and Coumarins. Synthesis and Cytotoxic Properties

Identification of a glutathione peroxidase inhibitor that reverses resistance to anticancer drugs in human B-cell lymphoma cell lines

In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent

In vitro anticancer activity and evaluation of DNA duplex binding affinity of phenyl-substituted indoloquinolines ⬇️

In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(ii) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light

Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors.

Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)] ⬇️

Investigation of the in vitro metabolism of the analgesic flupirtine

Light-activated destruction of cancer cell nuclei by platinum diazide complexes

Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.

Microwave-assisted synthesis and evaluation of acylhydrazones as potential inhibitors of bovine glutathione peroxidase

Nicotinamide adenine dinucleotide phosphate-regenerating system coupled to a glutathione-reductase microtiter method for determination of total glutathione concentrations in adherent growing cancer cell lines

No correlation between GSH levels in human cancer cell lines and the cell growth inhibitory activities of platinum diamine complexes.

Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure-Activity Relationship Study

Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines

Nucleotide Platination Induced by Visible Light

Oxidation potentials of N-modified derivatives of the analgesic flupirtine linked to potassium KV 7 channel opening activity but not hepatocyte toxicity.

Pentathiepins: a novel class of glutathione peroxidase 1 inhibitors that induce oxidative stress, loss of mitochondrial membrane potential and apoptosis in human cancer cells

Pharmacological Evaluation of the Anticancer Activity of Extracts and Fractions of Lannea barteri Oliv. (Anacardiaceae) on Adherent Human Cancer Cell Lines

Photoactivatable platinum complexes

Photoactivation of Diiodido-Pt(IV) Complexes Coupled to Upconverting Nanoparticles

Photosensitizers for Photodynamic Therapy: Photochemistry in the Service of Oncology

Quantification of elastase-like activity in 13 human cancer cell lines and in an immortalized human epithelial cell line by RP-HPLC.

Quantitative LC-MS/MS determination of flupirtine, its N-acetylated and two mercapturic acid derivatives in man

Structural diversity of copper(II) complexes with N-(2-pyridyl)imidazolidin-2-ones(thiones) and their in vitro antitumor activity.

Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.

Structure-activity relationships of targeted RuII(η6-p-cymene) anticancer complexes with flavonol-derived ligands

Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra

Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.

Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(iv) complexes ⬇️

Sulfide Analogues of Flupirtine and Retigabine with Nanomolar KV 7.2/KV 7.3 Channel Opening Activity

Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines.

Synthesis and Preliminary Cytotoxicity Studies of 1-[1-(4,5-Dihydrooxazol-2-yl)-1H-indazol-3-yl]-3-phenylurea and 3-phenylthiourea Derivatives

Synthesis and anticancer activity of novel 2-amino-4-(4-phenylpiperazino)- 1,3,5-triazine derivatives.

Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines.

Synthesis and biological activity of some 2-imidazolinylhydrazone derivatives.

Synthesis and cytotoxic activity of imidazo[1,2-a]-1,3,5-triazine analogues of 6-mercaptopurine

Synthesis and cytotoxicity testing of novel 2-(3-substituted-6-chloro-1,1-dioxo-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinones

Synthesis and in vitro anti-tumor activity of N-{1-[(3-thioxo-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene}arylsulfonamides

Synthesis and potassium K7 channel opening activity of thioether analogues of the analgesic flupirtine

Synthesis of N-(2-pyridyl)imidazolidin-2-ones and 1-(2-pyridyl)-2,3,7,8-tetrahydro-1H-imidazo[2,1-b][1,3,5]triazepin-5(6H)-ones with potential biological activities

Synthesis of aza-aromatic hydroxylamine-O-sulfonates and their application to tandem nucleophilic addition–electrophilic 5-endo-trig cyclization

Synthesis of indirubin-N'-glycosides and their anti-proliferative activity against human cancer cell lines.

Synthesis of novel aryl(heteroaryl)sulfonyl ureas of possible biological interest

Synthesis, Structure and Cytotoxicity Testing of Novel 7-(4,5-dihydro-1<i>H</i>-imidazol-2-yl)-2-aryl-6,7-dihydro-2<i>H</i>-imidazo[2,1-<i>c</i>][1,2,4]triazol-3(5<i>H</i>)-Imine Derivatives

Synthesis, Structure, Chemical Stability, and In Vitro Cytotoxic Properties of Novel Quinoline-3-Carbaldehyde Hydrazones Bearing a 1,2,4-Triazole or Benzotriazole Moiety

Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles

Synthesis, crystal structure and biological activities of copper(II) complexes with chelating bidentate 2-substituted benzimidazole ligands

Synthesis, crystal structure, cytotoxic and superoxide dismutase activities of copper(II) complexes of N-(4,5-dihydroimidazol-2-yl)azoles

Synthesis, cytotoxicity testing, and structure-activity relationships of novel 6-chloro-7-(4-phenylimino-4H-3,1-benzoxazin-2-yl)-3-(substituted)-1,4,2-benzodithiazine 1,1-dioxides

Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates

Synthesis, reactions and structure-activity relationships of 1-hydroxyspiro[2.5]cyclooct-4-en-3-ones: illudin analogs with in vitro cytotoxic activity

Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides

The Effect of Glutathione Peroxidase-1 Knockout on Anticancer Drug Sensitivities and Reactive Oxygen Species in Haploid HAP-1 Cells

Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism.