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11C-sorafenib and 15O-H2O PET for early evaluation of sorafenib therapy

artículo científico publicado en 2020

18th European Symposium on Radiopharmacy and Radiopharmaceuticals

article

89Zr-immuno-PET for imaging of long circulating drugs and disease targets: why, how and when to be applied?

artículo científico publicado en 2014

ABCG2- and ABCB1 Inhibition Using Supratherapeutic Doses of Erlotinib: Clinical Implications in the Treatment of Central Nervous System Metastases

artículo científico publicado en 2019

Absolute Quantification of [11C]docetaxel Kinetics in Lung Cancer Patients Using Positron Emission Tomography

scientific article published on 12 July 2011

Altered GABAA receptor density and unaltered blood-brain barrier [11C]flumazenil transport in drug-resistant epilepsy patients with mesial temporal sclerosis

artículo científico publicado en 2015

An oncological view on the blood-testis barrier.

artículo científico publicado en 2002

Bench to bedside development of GMP grade Rhenium-188-HEDP, a radiopharmaceutical for targeted treatment of painful bone metastases

artículo científico publicado en 2014

Biochemical Persistence of Prostate-specific Antigen after Robot-assisted Laparoscopic Radical Prostatectomy: Tumor localizations using PSMA PET/CT imaging

artículo científico publicado en 2020

Biodistribution and radiation dosimetry of 11C-labelled docetaxel in cancer patients

artículo científico publicado en 2010

Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

artículo científico publicado en 2005

Cytotoxic Effects of the Therapeutic Radionuclide Rhenium-188 Combined with Taxanes in Human Prostate Carcinoma Cell Lines

artículo científico publicado en 2017

Detecting resistance in EGFR-mutated non-small-cell lung cancer after clonal selection through targeted therapy.

artículo científico publicado en 2015

Detection of prostate cancer with 18F-DCFPyL PET/CT compared to final histopathology of radical prostatectomy specimens: is PSMA-targeted biopsy feasible? The DeTeCT trial

artículo científico publicado en 2020

Development of [(11)C]erlotinib positron emission tomography for in vivo evaluation of EGF receptor mutational status.

artículo científico publicado en 2012

Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?

scientific article published on 14 September 2019

Dried blood spot sampling of nilotinib in patients with chronic myeloid leukaemia: a comparison with venous blood sampling.

artículo científico publicado en 2017

Drug composition matters: the influence of carrier concentration on the radiochemical purity, hydroxyapatite affinity and in-vivo bone accumulation of the therapeutic radiopharmaceutical 188Rhenium-HEDP

artículo científico publicado en 2015

Dynamics of multidrug resistance: P-glycoprotein analyses with positron emission tomography

artículo científico publicado en 2002

Effective Drug Delivery in Diffuse Intrinsic Pontine Glioma: A Theoretical Model to Identify Potential Candidates

artículo científico publicado en 2017

Effects of Food on the Pharmacokinetics of Nilotinib in Chronic Myeloid Leukemia: Enabling Significant Dose Reduction and Relief of Treatment Burden: The NIFO-Study

scholarly article

Effects of erlotinib therapy on [(11)C]erlotinib uptake in EGFR mutated, advanced NSCLC.

artículo científico publicado en 2016

Enhanced cerebral uptake of receptor ligands by modulation of P-glycoprotein function in the blood-brain barrier

artículo científico publicado en 2000

Enzymatic synthesis of [4-methoxy-11C]daunorubicin for functional imaging of P-glycoprotein with PET

artículo científico publicado en 1998

Feasibility of and patients' perspective on nilotinib dried blood spot self-sampling

scientific article published on 07 February 2019

Food-effect study of nilotinib in chronic myeloid leukaemia (NiFo study): Enabling dose reduction and relief of treatment burden

scientific article published on 03 April 2020

Imaging of TKI-target interactions for personalized cancer therapy

artículo científico publicado en 2012

Immuno-Positron Emission Tomography with Zirconium-89-Labeled Monoclonal Antibodies in Oncology: What Can We Learn from Initial Clinical Trials?

artículo científico publicado en 2016

In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically.

artículo científico publicado en 2007

In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein.

artículo científico publicado en 2004

In vivo measurement of [11C]verapamil kinetics in human tissues.

artículo científico publicado en 2001

Individualized treatment planning in oncology: role of PET and radiolabelled anticancer drugs in predicting tumour resistance

artículo científico publicado en 2008

Irradiation of rat brain reduces P-glycoprotein expression and function.

artículo científico publicado en 2007

Locally increased P-glycoprotein function in major depression: a PET study with [11C]verapamil as a probe for P-glycoprotein function in the blood-brain barrier

artículo científico publicado en 2009

Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages

artículo científico publicado en 2015

Molecular Imaging of ABCB1/ABCG2 Inhibition at the Human Blood Brain Barrier using Elacridar and 11C-Erlotinib PET.

artículo científico publicado en 2017

Molecular imaging of targeted therapies with positron emission tomography: the visualization of personalized cancer care

artículo científico publicado en 2014

Needs for information and reasons for (non)adherence in chronic myeloid leukaemia: Be aware of social activities disturbing daily routines

scientific article published on 30 July 2018

New positron emission tomography tracer [(11)C]carvedilol reveals P-glycoprotein modulation kinetics

artículo científico publicado en 2005

P-glycoprotein at the blood-brain barrier and analysis of drug transport with positron-emission tomography.

artículo científico publicado en 2001

PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS.

artículo científico publicado en 2004

PSMA PET/CT in the Evaluation of Initial Response in Candidates Who Underwent Salvage Radiation Therapy after Radical Prostatectomy for Prostate Cancer

artículo científico publicado en 2020

Patient satisfaction with information on oral anticancer agent use.

artículo científico publicado en 2017

Pediatric microdose and microtracer studies using 14C in Europe.

artículo científico publicado en 2015

Pediatric microdose study of [(14)C]paracetamol to study drug metabolism using accelerated mass spectrometry: proof of concept

artículo científico publicado en 2014

Peripheral metabolism of [(18)F]FDDNP and cerebral uptake of its labelled metabolites

artículo científico publicado en 2008

Personalizing NSCLC therapy by characterizing tumors using TKI-PET and immuno-PET.

artículo científico publicado en 2016

Pharmaceutical and clinical development of phosphonate-based radiopharmaceuticals for the targeted treatment of bone metastases

artículo científico publicado en 2016

Pharmaceutical preparation of oxygen-15 labelled molecular oxygen and carbon monoxide gasses in a hospital setting

artículo científico publicado en 2010

Phase I trial of <sup>131</sup>I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients

artículo científico publicado en 2020

Pilot Study on the Feasibility of PET/CT Lymphoscintigraphy with 89Zr-Nanocolloidal Albumin for Sentinel Node Identification in Oral Cancer Patients

artículo científico publicado en 2013

Positron emission tomography for modeling pathophysiological processes in vivo.

artículo científico publicado en 2008

Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain.

artículo científico publicado en 2005

Quantification of 11C-Laniquidar Kinetics in the Brain

artículo científico publicado en 2015

Quantification of 18F-fluorocholine kinetics in patients with prostate cancer.

artículo científico publicado en 2015

Quantification of [18F]afatinib using PET/CT in NSCLC patients: a feasibility study

artículo científico publicado en 2020

Quantitative Parametric Perfusion Images Using 15O-Labeled Water and a Clinical PET/CT Scanner: Test-Retest Variability in Lung Cancer

scientific article published on 18 October 2010

Quantitative and Simplified Analysis of 11C-Erlotinib Studies

artículo científico publicado en 2016

Quantitative assessment of P-glycoprotein function in the rat blood-brain barrier by distribution volume of [11C]verapamil measured with PET.

artículo científico publicado en 2003

Radiation dose of the P-glycoprotein tracer 11C-laniquidar

artículo científico publicado en 2013

Radiolabeled drugs and PET imaging for personalized medicine

artículo científico publicado en 2018

Rapid decrease in delivery of chemotherapy to tumors after anti-VEGF therapy: implications for scheduling of anti-angiogenic drugs.

artículo científico publicado en 2012

Re: Sarcoid-like reaction to malignancy on whole-body integrated (18)F-FDG PET/CT: prevalence and disease pattern

scientific article published on 11 November 2009

Regional increase in P-glycoprotein function in the blood-brain barrier of patients with chronic schizophrenia: a PET study with [(11)C]verapamil as a probe for P-glycoprotein function

artículo científico publicado en 2010

Repeatability of Quantitative 18F-DCFPyL PET/CT Measurements in Metastatic Prostate Cancer

scientific article published on 10 January 2020

Reply: Quantification of 18F-DCFPyL Uptake: TBR Versus Patlak's Analysis

scientific article published on 26 August 2019

Response and Adherence to Nilotinib in Daily practice (RAND study): an in-depth observational study of chronic myeloid leukemia patients treated with nilotinib

scientific article published on 02 June 2020

Satisfaction with information on nilotinib treatment in chronic myeloid leukemia patients

scientific article published on 25 March 2019

Simplified Methods for Quantification of 18F-DCFPyL Uptake in Patients with Prostate Cancer

scientific article published on 18 April 2019

Successful Use of [14C]Paracetamol Microdosing to Elucidate Developmental Changes in Drug Metabolism

artículo científico publicado en 2017

Synthesis of [3-N-(11) C-methyl]temozolomide via in situ activation of 3-N-hydroxymethyl temozolomide and alkylation with [(11) C]methyl iodide.

artículo científico publicado en 2015

The Predictive Value of Preoperative Negative Prostate Specific Membrane Antigen Positron Emission Tomography Imaging for Lymph Node Metastatic Prostate Cancer

artículo científico publicado en 2021

The Predictive Value of Preoperative Negative Prostate Specific Membrane Antigen Positron Emission Tomography Imaging for Lymph Node Metastatic Prostate Cancer

artículo científico publicado en 2021

The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours.

artículo científico publicado en 2004

The navigating and de-risking role of <sup>89</sup>Zr-immuno-PET in the development of biopharmaceuticals

artículo científico publicado en 2020

The oral bioavailability and metabolism of midazolam in stable critically ill children: a pharmacokinetic microtracing study

artículo científico publicado en 2020

Toward prediction of efficacy of chemotherapy: a proof of concept study in lung cancer patients using [¹¹C]docetaxel and positron emission tomography.

artículo científico publicado en 2013

Treatment of painful bone metastases in prostate and breast cancer patients with the therapeutic radiopharmaceutical rhenium-188-HEDP. Clinical benefit in a real-world study.

artículo científico publicado en 2016

Untangling the web of European regulations for the preparation of unlicensed radiopharmaceuticals: a concise overview and practical guidance for a risk-based approach.

artículo científico publicado en 2015

Using prostate‐specific membrane antigen positron‐emission tomography to guide prostate biopsies and stage men at high‐risk of prostate cancer

artículo científico publicado en 2023

Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer

artículo científico publicado en 2018

[11C]Flumazenil brain uptake is influenced by the blood-brain barrier efflux transporter P-glycoprotein

artículo científico publicado en 2012

[11C]docetaxel and positron emission tomography for noninvasive measurements of docetaxel kinetics

artículo científico publicado en 2007

[¹¹C]Sorafenib: radiosynthesis and preclinical evaluation in tumor-bearing mice of a new TKI-PET tracer

artículo científico publicado en 2013