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A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice

artículo científico publicado en 2009

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

artículo científico publicado en 2010

Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide

artículo científico publicado en 2012

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain

artículo científico publicado en 2011

Behavioral deficits, early gliosis, dysmyelination and synaptic dysfunction in a mouse model of mucolipidosis IV.

artículo científico publicado en 2014

Caspase activation precedes and leads to tangles

artículo científico publicado en 2010

Changes in the progression of amyloid deposition in APP/PS mice after overexpression of different ApoE isoforms through intraventricular injection of an adeno-associated virus serotype 4

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

artículo científico publicado en 2005

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

artículo científico publicado en 2009

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model

artículo científico publicado en 2007

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

artículo científico publicado en 2008

Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease

artículo científico publicado en 2012

Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease.

artículo científico publicado en 2006

Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging

artículo científico publicado en 2010

Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo

artículo científico publicado en 2013

Neurofibrillary tangles remain functionally integrated in cortical networks

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

artículo científico publicado en 2008

Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2016

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

artículo científico publicado en 2008

Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice

artículo científico publicado en 2013

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain

artículo científico publicado en 2017

Stable size distribution of amyloid plaques over the course of Alzheimer disease

artículo científico publicado en 2012

Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy

artículo científico publicado en 2013

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy

artículo científico publicado en 2008