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2-Chlorodeoxyadenosine alone and in combination with cyclophosphamide and mitoxantrone induce apoptosis in B chronic lymphocytic leukemia cells in vivo

scientific article published on 01 January 2004

A 5-year follow-up to evaluate the efficacy and safety of ofatumumab added to fludarabine and cyclophosphamide in patients with relapsed chronic lymphocytic leukemia: final analysis of the COMPLEMENT 2 trial

scientific article published on 28 February 2020

Activity of cladribine combined with cyclophosphamide in frontline therapy for chronic lymphocytic leukemia with 17p13.1/TP53 deletion: report from the Polish Adult Leukemia Group

artículo científico publicado en 2009

Antibody therapy alone and in combination with targeted drugs in chronic lymphocytic leukemia

artículo científico publicado en 2016

Apoptotic gene expression under influence of fludarabine and cladribine in chronic lymphocytic leukemia-microarray study

artículo científico publicado el 1 de enero de 2012

Bendamustine alone or with rituximab modifies expression of apoptosis-regulating genes and proteins of CLL cells, depending on IGVH mutational status

artículo científico publicado en 2018

Calorimetric study as a potential test for choosing treatment of B-cell chronic lymphocytic leukemia

artículo científico publicado en 2008

Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment

artículo científico publicado en 2011

Changes in leukemic cell nuclei revealed by differential scanning calorimetry.

artículo científico publicado en 2005

Changes in the apoptotic gene expression profile in CLL patients treated with rituximab combined with cladribine and cyclophosphamide-preliminary results

article

Chromosomal aberrations in chronic lymphocytic leukemia detected by conventional cytogenetics with DSP30 as a single agent: comparison with FISH

artículo científico publicado en 2011

Circulating proangiogenic cytokines and angiogenesis inhibitor endostatin in untreated patients with chronic lymphocytic leukemia

artículo científico publicado en 2003

Circulating vascular endothelial growth factor (VEGF) and its soluble receptors in patients with chronic lymphocytic leukemia

artículo científico publicado en 2005

Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (

scientific article published on 21 March 2006

Cladribine combined with cyclophosphamide and mitoxantrone is an active salvage therapy in advanced non-Hodgkin's lymphoma.

artículo científico publicado en 2007

Cladribine combined with cyclophosphamide is highly effective in the treatment of chronic lymphocytic leukemia

artículo científico publicado en 2002

Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial.

artículo científico publicado en 2007

Clonal evolution in CLL patients as detected by FISH versus chromosome banding analysis, and its clinical significance.

artículo científico publicado en 2013

Comparison of cladribine plus cyclophosphamide with fludarabine plus cyclophosphamide as first-line therapy for chronic lymphocytic leukemia: a phase III randomized study by the Polish Adult Leukemia Group (PALG-CLL3 Study).

artículo científico publicado en 2010

Comparison of cladribine plus prednisone with chlorambucil plus prednisone in patients with chronic lymphocytic leukemia. Final report of the Polish Adult Leukemia Group (PALG CLL1).

artículo científico publicado en 2005

Cytotoxic and apoptosis-inducing effects of bendamustine used alone and in combination with rituximab on chronic lymphocytic leukemia cells in vitro

scientific article published on 05 December 2014

Determination of the in vivo effects of cladribine alone and its combination with cyclophosphamide or cyclophosphamide and mitoxantrone on Bax and Bcl-2 protein expression in B-CLL cells

artículo científico publicado en 2004

Dose and drug changes in chronic lymphocytic leukemia cell response in vitro: A comparison of standard therapy regimens with two novel cyclin‑dependent kinase inhibitors

artículo científico publicado en 2019

Evaluation of circulating endothelial cells as noninvasive marker of angiogenesis in patients with chronic lymphocytic leukemia

artículo científico publicado en 2009

Forodesine (BCX-1777, Immucillin H)--a new purine nucleoside analogue: mechanism of action and potential clinical application

artículo científico publicado en 2007

Health-related quality of life and patient-reported outcomes of ofatumumab plus fludarabine and cyclophosphamide versus fludarabine and cyclophosphamide in the COMPLEMENT 2 trial of patients with relapsed CLL.

artículo científico publicado en 2016

Immune thrombocytopenia in patients with chronic lymphocytic leukemia treated with cladribine-based regiments or chlorambucil--follow-up of PALG-CLL randomized trials.

artículo científico publicado en 2013

In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification

artículo científico publicado en 2016

In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone

artículo científico publicado en 2006

In vivo and ex vivo responses of CLL cells to purine analogs combined with alkylating agent.

artículo científico publicado en 2013

Influence of cladribine alone and in combination with cyclophosphamide or cyclophosphamide and mitoxantrone on bone marrow angiogenesis in chronic lymphocytic leukemia

artículo científico publicado en 2007

Langerhans cell histiocytosis in a patient with systemic lupus erythematosus: a clonal disease responding to treatment with cladribine, and cyclophosphamide

artículo científico publicado en 2002

Long-term results of the Polish Adult Leukemia Group PALG-CLL2 phase III randomized study comparing cladribine-based combinations in chronic lymphocytic leukemia.

artículo científico publicado en 2013

Ofatumumab plus fludarabine and cyclophosphamide in relapsed chronic lymphocytic leukemia: results from the COMPLEMENT 2 trial.

artículo científico publicado en 2016

Personalized therapy tests for the monitoring of chronic lymphocytic leukemia development

artículo científico publicado en 2017

Prognostic value of the bone marrow microvessel density in progressive B-cell chronic lymphocytic leukemia

artículo científico publicado en 2010

Prognostic value of thymidine kinase activity in patients with chronic lymphocytic leukemia

artículo científico publicado en 2016

Promising anti-leukemic activity of atorvastatin.

artículo científico publicado en 2013

R-roscovitine (Seliciclib) affects CLL cells more strongly than combinations of fludarabine or cladribine with cyclophosphamide: Inhibition of CDK7 sensitizes leukemic cells to caspase-dependent apoptosis

artículo científico publicado en 2010

Re-treatment with cladribine-based regimens in relapsed patients with B-cell chronic lymphocytic leukemia. Efficacy and toxicity in comparison with previous treatment

artículo científico publicado en 2002

Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma

artículo científico publicado en 2006

Rituximab followed by cladribine in the treatment of heavily pretreated patients with indolent lymphoid malignancies.

artículo científico publicado en 2004

Rituximab plus cladribine with or without cyclophosphamide in patients with relapsed or refractory chronic lymphocytic leukemia

artículo científico publicado en 2007

Rituximab, cladribine and cyclophosphamide (RCC) induction with rituximab maintenance in chronic lymphocytic leukemia: PALG - CLL4 (ML21283) trial.

artículo científico publicado en 2018

Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide

artículo científico publicado en 2009

The differences in thermal profiles between normal and leukemic cells exposed to anticancer drug evaluated by differential scanning calorimetry

The effect of subsequent therapies in patients with chronic lymphocytic leukemia previously treated with prednisone and either cladribine or chlorambucil.

artículo científico publicado en 2005

Toward personalized therapy for chronic lymphocytic leukemia: DSC and cDNA microarray assessment of two cases

artículo científico publicado en 2012

Towards the Application of Atorvastatin to Intensify Proapoptotic Potential of Conventional Antileukemic AgentsIn Vitro

scholarly article in Journal of Chemistry, 2015