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A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma

artículo científico publicado en 2011

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population

scientific journal article

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

artículo científico publicado en 2009

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci

artículo científico publicado en 2010

A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis

artículo científico publicado en 2005

A novel method for analyzing formalin-fixed paraffin embedded (FFPE) tissue sections by mass spectrometry imaging

artículo científico publicado en 2007

A novel tumor‐associated antigen, cell division cycle 45‐like can induce cytotoxic T‐lymphocytes reactive to tumor cells

artículo científico publicado el 10 de febrero de 2011

ADAM8 as a novel serological and histochemical marker for lung cancer

artículo científico publicado en 2004

ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway

artículo científico publicado en 2005

Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis

artículo científico publicado en 2006

Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells

artículo científico publicado en 2007

Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis

artículo científico

Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer

artículo científico publicado en 2009

Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis

artículo científico

Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients

artículo científico

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

artículo científico publicado en 2016

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

artículo científico publicado en 2010

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

artículo científico publicado en 2016

Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients

artículo científico publicado en 2009

Biphasic prognostic significance of PD-L1 expression status in patients with early- and locally advanced-stage non-small cell lung cancer

artículo científico publicado en 2020

C12orf48, termed PARP‐1 binding protein, enhances poly(ADP‐ribose) polymerase‐1 (PARP‐1) activity and protects pancreatic cancer cells from DNA damage

artículo científico publicado el 1 de enero de 2011

Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer

artículo científico publicado en 2016

Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers

artículo científico publicado en 2013

Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer

artículo científico publicado en 2017

Characterization of KIF20A as a prognostic biomarker and therapeutic target for different subtypes of breast cancer

artículo científico publicado en 2020

Characterization of URST1 as a new prognostic biomarker and therapeutic target for breast cancer

artículo científico publicado en 2017

Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer

artículo científico publicado en 2011

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis

artículo científico

Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer

artículo científico

Clinical significance of PD-L1-positive cancer-associated fibroblasts in pN0M0 non-small cell lung cancer

scientific article published on 16 September 2019

Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer

artículo científico publicado en 2014

Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count

scientific article published on 18 February 2010

Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer

artículo científico publicado en 2007

Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis

artículo científico publicado en 2012

Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.

artículo científico publicado en 2009

Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer

artículo científico publicado en 2011

Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition

artículo científico publicado en 2013

Detection of neoantigen-reactive T cell clones based on the clonal expansion using next-generation sequencing of T cell receptor β complementarity-determining region 3

scientific article published on 23 October 2019

Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma

artículo científico publicado en 2008

Development of Serum Glycoproteomic Profiling Technique; Simultaneous Identification of Glycosylation Sites and Site-Specific Quantification of Glycan Structure Changes

artículo científico publicado el 1 de septiembre de 2010

Differential gene expression in the murine gastric fundus lacking interstitial cells of Cajal

artículo científico publicado en 2003

Differential gene expression profile in the small intestines of mice lacking pacemaker interstitial cells of Cajal

artículo científico publicado en 2003

Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas

artículo científico

Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.

artículo científico publicado en 2007

Erratum: Corrigendum: Regulation of histone modification and chromatin structure by the p53–PADI4 pathway

artículo científico publicado en 2013

Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray.

artículo científico publicado en 2006

Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs

artículo científico publicado en 2003

Expression profiles of two types of human knee-joint cartilage

artículo científico publicado en 2003

Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer

artículo científico publicado en 2007

From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma

artículos científicos

Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.

artículo científico publicado en 2003

Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice

artículo científico publicado el 1 de mayo de 2003

Genome-wide association study of hematological and biochemical traits in a Japanese population

artículo científico publicado en 2010

Genome-wide association study of pancreatic cancer in Japanese population

artículo científico publicado en 2010

Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas

artículo científico publicado en 2006

HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.

artículo científico publicado en 2008

Identification and validation of prognostic markers in breast cancer with the complementary use of array-CGH and tissue microarrays

artículo científico publicado en 2005

Identification of COX17 as a therapeutic target for non-small cell lung cancer

artículo científico publicado el 1 de noviembre de 2003

Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer

artículo científico publicado en 2011

Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer

artículo científico publicado en 2007

Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis

artículo científico publicado en 2012

Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis

artículo científico publicado en 2014

Identification of candidate lung cancer neoantignes by next generation sequencing towards precision medicine

artículo científico publicado en 2017

Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy

artículo científico publicado en 2007

Identification of immunogenic LY6K long peptide encompassing both CD4(+) and CD8(+) T-cell epitopes and eliciting CD4(+) T-cell immunity in patients with malignant disease

artículo científico publicado en 2014

Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer

artículo científico

Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers

artículo científico publicado en 2005

Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.

artículo científico publicado en 2009

Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells

artículo científico publicado en 2009

Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.

artículo científico

Isolation of novel mouse genes that were differentially expressed in W/W(V) mouse fundus

artículo científico publicado en 2004

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

artículo científico publicado en 2020

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

artículo científico publicado en 2016

Mutations truncating the EP300 acetylase in human cancers

Novel human and mouse genes encoding a shank-interacting protein and its upregulation in gastric fundus of W/WV mouse

artículo científico publicado en 2003

Novel human, mouse and xenopus genes encoding a member of the RAS superfamily of low-molecular-weight GTP-binding proteins and its downregulation in W/WV mouse jejunum

artículo científico publicado en 2004

Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma

artículo científico publicado en 2009

Overexpression of CDC20 predicts poor prognosis in primary non-small cell lung cancer patients.

artículo científico publicado en 2012

Overexpression of KIAA0101 predicts poor prognosis in primary lung cancer patients

artículo científico publicado en 2012

Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients

artículo científico publicado el 4 de marzo de 2011

Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis

artículo científico publicado en 2010

Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis

artículo científico publicado en 2007

Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer

artículo científico publicado en 2005

Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.

artículo científico publicado en 2004

Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).

artículo científico publicado en 2004

Predictive biomarkers and effectiveness of MUC1-targeted dendritic-cell-based vaccine in patients with refractory non-small cell lung cancer

artículo científico publicado en 2016

Prognostic value of EGFR mutations in surgically resected pathological stage I lung adenocarcinoma

artículo científico publicado en 2016

Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor α and β chains using next-generation sequencing (NGS)

artículo científico publicado en 2014

Quantitative analysis and clonal characterization of T-cell receptor β repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine

artículo científico publicado en 2017

RAS-Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers

artículo científico publicado en 2016

RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer

artículo científico publicado en 2013

Regulation of histone modification and chromatin structure by the p53–PADI4 pathway

artículo científico publicado en 2012

Regulation of iron homeostasis by the p53-ISCU pathway

artículo científico publicado en 2015

Scoring of PD-L1 expression intensity on pulmonary adenocarcinomas and the correlations with clinicopathological factors.

artículo científico publicado en 2016

Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays

artículo científico publicado en 2009

The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy

artículo científico publicado en 2010

The mechanism of de novo expression of programmed cell death-ligand 1 in squamous cell carcinoma of the lung

artículo científico

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

artículo científico publicado en 2019

Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer

artículo científico publicado en 2009

Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

artículo científico publicado en 2011

Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations

scientific article published on 26 September 2010

Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy

artículo científico publicado en 2010

p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels

artículo científico publicado en 2004