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A combined clinical and biomarker approach to predict diuretic response in acute heart failure

artículo científico publicado en 2015

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure

artículo científico publicado en 2017

Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study

artículo científico publicado en 2016

Acute heart failure clinical drug development: from planning to proof of activity to phase III.

artículo científico publicado en 2010

Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial

article

Acute heart failure in the young: Clinical characteristics and biomarker profiles

artículo científico publicado en 2016

Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure

artículo científico

Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction

artículo científico publicado en 2017

Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure

artículo científico

Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure

artículo científico publicado en 2016

Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment e

artículo científico publicado en 2009

Diuretic response in acute heart failure: clinical characteristics and prognostic significance.

artículo científico publicado en 2014

Dyspnoea in patients with acute heart failure: an analysis of its clinical course, determinants, and relationship to 60-day outcomes in the PROTECT pilot study

artículo científico publicado en 2010

Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study

artículo científico publicado en 2011

Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial

artículo científico publicado en 2015

Effects of the Adenosine A1 Receptor Antagonist Rolofylline on Renal Function in Patients With Acute Heart Failure and Renal Dysfunction

article

Fluid overload in acute heart failure--re-distribution and other mechanisms beyond fluid accumulation

artículo científico publicado en 2008

HETEROGENEITY IN EFFICACY OF ROLOFYLLINE USING A RISK-BASED EVALUATION IN PATIENTS HOSPITALIZED WITH ACUTE HEART FAILURE

Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function

artículo científico publicado en 2010

Identifying Subpopulations with Distinct Response to Treatment Using Plasma Biomarkers in Acute Heart Failure: Results from the PROTECT Trial : Differential Response in Acute Heart Failure

artículo científico publicado en 2017

Impact of serial troponin release on outcomes in patients with acute heart failure: analysis from the PROTECT pilot study

artículo científico

Improvements in signs and symptoms during hospitalization for acute heart failure follow different patterns and depend on the measurement scales used: an international, prospective registry to evaluate the evolution of measures of disease severity i

artículo científico publicado en 2008

MicroRNAs relate to early worsening of renal function in patients with acute heart failure

artículo científico publicado en 2015

Optimizing clinical use of biomarkers in high-risk acute heart failure patients

artículo científico publicado en 2015

Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality

artículo científico

Physician-determined worsening heart failure: a novel definition for early worsening heart failure in patients hospitalized for acute heart failure--association with signs and symptoms, hospitalization duration, and 60-day outcomes

artículo científico publicado en 2009

Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure

artículo científico publicado en 2017

Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome

artículo científico publicado en 2015

Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure

artículo científico publicado en 2018

Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients

artículo científico publicado en 2015

Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion

Renal function trajectories and clinical outcomes in acute heart failure

artículo científico publicado en 2013

Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial

artículo científico publicado en 2016

Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure

artículo científico publicado en 2010

Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials).

artículo científico publicado en 2016

Sex-specific acute heart failure phenotypes and outcomes from PROTECT.

artículo científico publicado en 2013

The PROTECT pilot study: a randomized, placebo-controlled, dose-finding study of the adenosine A1 receptor antagonist rolofylline in patients with acute heart failure and renal impairment

artículo científico publicado en 2008

The effects of adenosine A(1) receptor antagonism in patients with acute decompensated heart failure and worsening renal function: the REACH UP study

artículo científico publicado en 2010

The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT.

artículo científico publicado en 2012

Trajectories of Changes in Renal Function in Patients with Acute Heart Failure

scientific article published on 15 July 2019

Vasodilators in the treatment of acute heart failure: what we know, what we don't

artículo científico publicado en 2009

Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies

artículo científico publicado en 2015

Worsening renal function in patients hospitalised for acute heart failure: clinical implications and prognostic significance.

artículo científico publicado en 2008

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