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A multimarker multi-time point-based risk stratification strategy in acute heart failure: results from the RELAX-AHF trial

artículo científico publicado en 2017

A roadmap for the prevention of dementia II: Leon Thal Symposium 2008.

artículo científico publicado en 2009

A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium

artículo científico publicado en 2008

Acute heart failure syndromes in patients with coronary artery disease early assessment and treatment

artículo científico publicado en 2009

Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).

artículo científico publicado en 2009

Anticoagulation in heart failure: current status and future direction

artículo científico publicado en 2013

Association between performance measures and clinical outcomes for patients hospitalized with heart failure

artículo científico publicado en 2007

CUPID 2: A Phase 2b Trial Investigating the Efficacy and Safety of the Intracoronary Administration of AAV1/SERCA2a in Patients with Advanced Heart Failure

Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial

artículo científico publicado en 2016

Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: An analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)

article

Cause of Death in Patients With Acute Heart Failure: Insights From RELAX-AHF-2

artículo científico publicado en 2020

Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry

artículo científico publicado en 2007

Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward

scientific article published on March 2010

Day of admission and clinical outcomes for patients hospitalized for heart failure: findings from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2008

Day vs night: Does time of presentation matter in acute heart failure? A secondary analysis from the RELAX-AHF trial

artículo científico publicado en 2017

Depression and Clinical Outcomes in Heart Failure: An OPTIMIZE-HF Analysis

article

Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b).

artículo científico publicado en 2014

Design of the RELAXin in acute heart failure study.

artículo científico publicado en 2012

Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010.

artículo científico publicado en 2011

Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.

artículo científico publicado en 2010

Diuretic response in patients with acute decompensated heart failure: characteristics and clinical outcome--an analysis from RELAX-AHF.

artículo científico publicado en 2014

Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure).

artículo científico publicado en 2008

Dyspnoea and worsening heart failure in patients with acute heart failure: results from the Pre-RELAX-AHF study

artículo científico publicado en 2010

Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre‐RELAX‐AHF

artículo científico publicado el 28 de mayo de 2011

Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes

artículo científico publicado en 2013

Effect of serelaxin on mode of death in acute heart failure: results from the RELAX-AHF study

artículo científico publicado en 2014

Effects of Serelaxin in Patients with Acute Heart Failure

scientific article published on 01 August 2019

Effects of serelaxin in acute heart failure patients with renal impairment: results from RELAX-AHF

artículo científico publicado en 2016

Effects of serelaxin in patients admitted for acute heart failure: a meta-analysis

artículo científico publicado en 2019

Effects of serelaxin in subgroups of patients with acute heart failure: results from RELAX-AHF

artículo científico publicado en 2013

Effects of serelaxin on the outcome of patients with or without substantial peripheral edema: A subgroup analysis from the RELAX-AHF trial

artículo científico publicado en 2017

Ejection fraction, B-type natriuretic peptide and risk of stroke and acute myocardial infarction among patients with heart failure

artículo científico publicado en 2019

Erratum to: Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial.

artículo científico publicado en 2017

Factors identified as precipitating hospital admissions for heart failure and clinical outcomes: findings from OPTIMIZE-HF.

artículo científico publicado en 2008

Growth differentiation factor 15 (GDF-15) in patients admitted for acute heart failure: results from the RELAX-AHF study

artículo científico publicado en 2015

Heart Failure Clinical Trials in East and Southeast Asia: Understanding the Importance and Defining the Next Steps

artículo científico publicado en 2016

Heart failure with reduced ejection fraction

artículo científico publicado en 2017

Hepatorenal dysfunction identifies high-risk patients with acute heart failure: insights from the RELAX-AHF trial

artículo científico publicado en 2019

Independent academic Data Monitoring Committees for clinical trials in cardiovascular and cardiometabolic diseases

artículo científico publicado en 2017

Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).

artículo científico

Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure: findings from the OPTIMIZE-HF program

artículo científico publicado en 2008

Influence of coronary angiography on the utilization of therapies in patients with acute heart failure syndromes: findings from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2009

Influence of coronary artery disease and coronary revascularization status on outcomes in patients with acute heart failure syndromes: A report from OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart F

article

Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: A report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)

article

Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: a report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2007

Low lymphocyte ratio as a novel prognostic factor in acute heart failure: results from the Pre-RELAX-AHF study.

artículo científico publicado en 2010

Mega-trials in heart failure: effects of dilution in examination of new therapies

scientific article published on 30 March 2020

Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and design

artículo científico publicado en 2004

Performance Measures and Outcomes for Patients Hospitalized With Heart Failure—Reply

artículo científico publicado en 2007

Permutation criteria to evaluate multiple clinical endpoints in a proof-of-concept study: lessons from Pre-RELAX-AHF

artículo científico publicado en 2011

Phase III clinical trial end points in acute heart failure syndromes: A virtual roundtable with the acute heart failure syndromes international working group

article

Predictors of Delivery of Hospital-Based Heart Failure Patient Education: A Report from OPTIMIZE-HF

article

Predictors of in-hospital mortality in patients hospitalized for heart failure: insights from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2008

Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2008

Prospective evaluation of beta-blocker use at the time of hospital discharge as a heart failure performance measure: results from OPTIMIZE-HF.

artículo científico publicado en 2007

Quality of care of and outcomes for African Americans hospitalized with heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry

artículo científico publicado en 2008

Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia

artículo científico publicado en 2008

Rationale and design of a randomized, double-blind, event-driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and

artículo científico publicado en 2015

Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry).

artículo científico publicado en 2008

Relationship between left ventricular ejection fraction and cardiovascular outcomes following hospitalization for heart failure: insights from the RELAX-AHF-2 trial

artículo científico publicado en 2020

Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease

article by Faiez Zannad et al published 4 October 2018 in The New England Journal of Medicine

Role of aldosterone blockade for treatment of heart failure and post-acute myocardial infarction

artículo científico publicado en 2006

Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial

artículo científico publicado en 2017

Serelaxin in acute heart failure patients with preserved left ventricular ejection fraction: results from the RELAX-AHF trial

artículo científico publicado en 2013

Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study

artículo científico publicado en 2017

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

artículo científico publicado en 2012

Serial high sensitivity cardiac troponin T measurement in acute heart failure: insights from the RELAX-AHF study

artículo científico publicado en 2015

Sex differences in early dyspnea relief between men and women hospitalized for acute heart failure: insights from the RELAX-AHF study

artículo científico publicado en 2016

Site enrollment rate, outcomes, and study drug effects in a multicenter trial. Results from RELAX-AHF.

artículo científico publicado en 2018

Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure

artículo científico publicado en 2006

The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial.

artículo científico publicado en 2011

Use of High-Sensitivity Troponin T to Identify Patients With Acute Heart Failure at Lower Risk for Adverse Outcomes: An Exploratory Analysis From the RELAX-AHF Trial

artículo científico publicado en 2016

Utility of Impedance Cardiography for the Identification of Short-Term Risk of Clinical Decompensation in Stable Patients With Chronic Heart Failure

article

Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies

artículo científico publicado en 2015