Lista de obras -

A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice

artículo científico publicado en 2014

A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence

artículo científico publicado en 2008

A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics.

artículo científico publicado en 2012

A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains

artículo científico publicado en 2016

Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

artículo científico publicado en 2005

An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections

article by Malak Kotb et al published 18 November 2002 in Nature Medicine

An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis

artículo científico publicado en 2008

Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.

artículo científico publicado en 2014

Commercial peptidoglycan preparations are contaminated with superantigen-like activity that stimulates IL-17 production

artículo científico publicado en 2007

DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps

artículo científico publicado en 2006

Detection of MDR1 single nucleotide polymorphisms C3435T and G2677T using real-time polymerase chain reaction: MDR1 single nucleotide polymorphism genotyping assay

artículo científico publicado en 2002

Development of a murine model for aerosolized ebolavirus infection using a panel of recombinant inbred mice

artículo científico publicado en 2012

Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria

artículo científico publicado en 2010

Etiology of autistic features: the persisting neurotoxic effects of propionic acid

artículo científico publicado en 2012

Expression of Transforming Growth Factor-β by Human Islets: Impact on Islet Viability and Function

artículo científico

Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

artículo científico publicado en 2013

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

artículo científico publicado en 2016

Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus

artículo científico publicado en 2006

Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase

artículo científico publicado en 2007

Host Genetic Variations and Sex Differences Potentiate Predisposition, Severity, and Outcomes of Group A Streptococcus-Mediated Necrotizing Soft Tissue Infections

artículo científico publicado en 2015

Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice

artículo científico publicado en 2009

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

artículo científico publicado en 2005

Individual Genetic Variations Directly Effect Polarization of Cytokine Responses to Superantigens Associated with Streptococcal Sepsis: Implications for Customized Patient Care ⬇️

artículo científico publicado el 31 de enero de 2011

Intracellular Streptococcus pyogenes in human macrophages display an altered gene expression profile

artículo científico publicado en 2012

Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.

artículo científico publicado en 2004

Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice

artículo científico publicado en 2015

Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications

artículo científico publicado en 2014

Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence

artículo científico publicado en 2010

Molecular requirements for MHC class II alpha-chain engagement and allelic discrimination by the bacterial superantigen streptococcal pyrogenic exotoxin C.

artículo científico publicado en 2008

Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes.

artículo científico publicado en 2005

Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection

artículo científico publicado en 2005

Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery

artículo científico publicado en 2002

Parameters governing invasive disease propensity of non-M1 serotype group A streptococci

artículo científico publicado en 2010

Prooxidant mechanisms in toxicology

artículo científico publicado en 2014

Quantitative detection of T-cell activation markers by real-time PCR in renal transplant rejection and correlation with histopathologic evaluation

artículo científico publicado en 2002

Rise and persistence of global M1T1 clone of Streptococcus pyogenes

scientific article published on October 2008

Role of group A Streptococcus HtrA in the maturation of SpeB protease

artículo científico publicado en 2007

Selective modulation of superantigen-induced responses by streptococcal cysteine protease

artículo científico publicado en 2003

Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis

artículo científico publicado en 2008

Soluble M1 protein of Streptococcus pyogenes triggers potent T cell activation

artículo científico publicado en 2007

Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality

artículo científico publicado en 2012

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

artículo científico publicado en 2013

Systemic Dysregulation of Angiopoietin-1 and -2 in Streptococcal Toxic Shock Syndrome

article

Toxicity of novel nanosized formulations used in medicine

artículo científico

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

artículo científico publicado en 2012

Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections

scientific article published in January 2008

Viable group A streptococci in macrophages during acute soft tissue infection

artículo científico publicado en 2006

Lista de obras de

A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice

A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence

A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics.

A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains

Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections

An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis

Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.

Commercial peptidoglycan preparations are contaminated with superantigen-like activity that stimulates IL-17 production

DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps

Detection of MDR1 single nucleotide polymorphisms C3435T and G2677T using real-time polymerase chain reaction: MDR1 single nucleotide polymorphism genotyping assay

Development of a murine model for aerosolized ebolavirus infection using a panel of recombinant inbred mice

Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria

Etiology of autistic features: the persisting neurotoxic effects of propionic acid

Expression of Transforming Growth Factor-β by Human Islets: Impact on Islet Viability and Function

Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus

Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase

Host Genetic Variations and Sex Differences Potentiate Predisposition, Severity, and Outcomes of Group A Streptococcus-Mediated Necrotizing Soft Tissue Infections

Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

Individual Genetic Variations Directly Effect Polarization of Cytokine Responses to Superantigens Associated with Streptococcal Sepsis: Implications for Customized Patient Care ⬇️

Intracellular Streptococcus pyogenes in human macrophages display an altered gene expression profile

Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.

Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice

Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications

Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence

Molecular requirements for MHC class II alpha-chain engagement and allelic discrimination by the bacterial superantigen streptococcal pyrogenic exotoxin C.

Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes.

Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection

Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery

Parameters governing invasive disease propensity of non-M1 serotype group A streptococci

Prooxidant mechanisms in toxicology

Quantitative detection of T-cell activation markers by real-time PCR in renal transplant rejection and correlation with histopathologic evaluation

Rise and persistence of global M1T1 clone of Streptococcus pyogenes

Role of group A Streptococcus HtrA in the maturation of SpeB protease

Selective modulation of superantigen-induced responses by streptococcal cysteine protease

Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis

Soluble M1 protein of Streptococcus pyogenes triggers potent T cell activation

Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

Systemic Dysregulation of Angiopoietin-1 and -2 in Streptococcal Toxic Shock Syndrome

Toxicity of novel nanosized formulations used in medicine

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections

Viable group A streptococci in macrophages during acute soft tissue infection