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A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes

scientific article published on February 2010

Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes.

artículo científico publicado en 2008

Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes

artículo científico publicado en 2013

Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B

artículo científico publicado en 2008

Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease.

artículo científico publicado en 2017

Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2.

artículo científico publicado en 2012

Developing an asymptomatic mucosal herpes vaccine: the present and the future

artículo científico publicado en 2010

Discovery of Potential Diagnostic and Vaccine Antigens in Herpes Simplex Virus 1 and 2 by Proteome-Wide Antibody Profiling ⬇️

artículo científico publicado el 8 de febrero de 2012

Engagement of TLR2 Reverses the Suppressor Function of Conjunctiva CD4+CD25+Regulatory T Cells and Promotes Herpes Simplex Virus Epitope-Specific CD4+CD25−Effector T Cell Responses ⬇️

artículo científico publicado el 17 de mayo de 2011

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

artículo científico publicado en 2007

Future Viral Vectors For the Delivery of Asymptomatic Herpes Epitope-based Immunotherapeutic Vaccines ⬇️

artículo científico publicado el 1 de septiembre de 2010

HIV-1 Infection Impairs HSV-Specific CD4+ and CD8+ T-Cell Response by Reducing Th1 Cytokines and CCR5 Ligand Secretion

article

HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D.

artículo científico publicado en 2008

Immunity to ocular and genital herpes simplex viruses infections

artículo científico publicado en 2012

Immunodominant “Asymptomatic” Herpes Simplex Virus 1 and 2 Protein Antigens Identified by Probing Whole-ORFome Microarrays with Serum Antibodies from Seropositive Asymptomatic versus Symptomatic Individuals ⬇️

artículo científico publicado el 8 de febrero de 2012

Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity

artículo científico publicado en 2010

Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections

artículo científico publicado en 2012

Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization

artículo científico publicado en 2010

New concepts in herpes simplex virus vaccine development: notes from the battlefield

artículo científico publicado en 2009

Of mice and not humans: How reliable are animal models for evaluation of herpes CD8+-T cell-epitopes-based immunotherapeutic vaccine candidates? ⬇️

artículo científico publicado el 28 de junio de 2011

Recent advances in multivalent self adjuvanting glycolipopeptide vaccine strategies against breast cancer

artículo científico publicado en 2009

Targeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88.

artículo científico publicado en 2012

The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8 + T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism ⬇️

artículo científico publicado el 29 de junio de 2011

The Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Protect Neuron-Derived C1300 and Neuro2A Cells from Granzyme B-Induced Apoptosis and CD8 T-Cell Killing ⬇️

artículo científico publicado el 22 de diciembre de 2010

The Herpes Simplex Virus Type 1 Latency-Associated Transcript Inhibits Phenotypic and Functional Maturation of Dendritic Cells ⬇️

artículo científico publicado el 18 de abril de 2012

Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of l

artículo científico publicado en 2015

Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknown

artículo científico publicado en 2012

Towards a self-adjuvanting multivalent B and T cell epitope containing synthetic glycolipopeptide cancer vaccine.

artículo científico publicado en 2008

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