Lista de obras -

A Platform for Rapid Detection of Multiple Oncogenic Mutations With Relevance to Targeted Therapy in Non–Small-Cell Lung Cancer ⬇️

artículo científico publicado el 23 de diciembre de 2010

A potential role for targeted therapy in a subset of metastasizing adnexal carcinomas ⬇️

artículo científico publicado el 18 de marzo de 2011

ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer

artículo científico publicado en 2013

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping

artículo científico publicado en 2016

Activation of PI3K signaling in Merkel cell carcinoma

artículo científico publicado en 2012

Apocrine-eccrine carcinomas: molecular and immunohistochemical analyses

artículo científico publicado en 2012

BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

artículo científico publicado en 2011

BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults

artículo científico publicado en 2013

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications

artículo científico publicado en 2011

BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation ⬇️

artículo científico publicado el 23 de noviembre de 2010

Characteristics of lung cancers harboring NRAS mutations

artículo científico publicado en 2013

Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations

artículo científico publicado en 2015

Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.

artículo científico publicado en 2016

Cytological, molecular, and clinical features of noninvasive follicular thyroid neoplasm with papillary-like nuclear features versus invasive forms of follicular variant of papillary thyroid carcinoma.

artículo científico publicado en 2017

De novo ALK kinase domain mutations are uncommon in kinase inhibitor-naïve ALK rearranged lung cancers

artículo científico publicado en 2016

Decreased survival in EGFR gene amplified vulvar carcinoma

artículo científico publicado en 2008

Detection of Dual IDH1 and IDH2 Mutations by Targeted Next-Generation Sequencing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

artículo científico publicado en 2015

Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment

artículo científico publicado en 2012

EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib

artículo científico publicado en 2012

Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma

artículo científico publicado en 2008

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

artículo científico publicado en 2014

Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping

artículo científico publicado en 2011

Genomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarker

artículo científico publicado en 2015

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

artículo científico publicado en 2011

Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

artículo científico publicado en 2015

Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas

artículo científico publicado en 2012

Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile

artículo científico publicado en 2014

Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis.

artículo científico publicado en 2015

Identification of mutations in CUL7 in 3-M syndrome

artículo científico publicado en 2005

Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma.

artículo científico publicado en 2014

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors

scientific article published on 05 November 2013

Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery

artículo científico publicado en 2014

Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.

artículo científico publicado en 2012

Malignant neurocristic hamartoma: a tumor distinct from conventional melanoma and malignant blue nevus

artículo científico

Merkel cell carcinoma: 30-year experience from a single institution

artículo científico

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model.

artículo científico publicado en 2015

Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience

artículo científico publicado en 2015

Mutational analysis and clinical correlation of metastatic colorectal cancer

artículo científico publicado en 2014

NRAS mutations are rare in colorectal cancer

artículo científico publicado en 2010

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

artículo científico publicado en 2016

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

artículo científico publicado en 2010

Primary Benign and Malignant Thyroid Neoplasms With Signet Ring Cells: Cytologic, Histologic, and Molecular Features.

artículo científico publicado en 2017

Prospective, high-throughput molecular profiling of human gliomas

artículo científico publicado en 2012

Pulmonary adenocarcinoma mutation profile in smokers with smoking-related interstitial fibrosis

artículo científico publicado en 2014

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

artículo científico publicado en 2010

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

artículo científico publicado en 2012

Standardized decision support in next generation sequencing reports of somatic cancer variants

artículo científico

Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models

artículo científico publicado en 2013

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

artículo científico publicado en 2014

Tau phosphorylation sites work in concert to promote neurotoxicity in vivo

artículo científico publicado en 2007

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation

artículo científico publicado en 2008

The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma.

artículo científico publicado en 2011

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

artículo científico publicado en 2014

Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis

artículo científico publicado en 2013

Lista de obras de

A Platform for Rapid Detection of Multiple Oncogenic Mutations With Relevance to Targeted Therapy in Non–Small-Cell Lung Cancer ⬇️

A potential role for targeted therapy in a subset of metastasizing adnexal carcinomas ⬇️

ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping

Activation of PI3K signaling in Merkel cell carcinoma

Apocrine-eccrine carcinomas: molecular and immunohistochemical analyses

BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications

BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation ⬇️

Characteristics of lung cancers harboring NRAS mutations

Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations

Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.

Cytological, molecular, and clinical features of noninvasive follicular thyroid neoplasm with papillary-like nuclear features versus invasive forms of follicular variant of papillary thyroid carcinoma.

De novo ALK kinase domain mutations are uncommon in kinase inhibitor-naïve ALK rearranged lung cancers

Decreased survival in EGFR gene amplified vulvar carcinoma

Detection of Dual IDH1 and IDH2 Mutations by Targeted Next-Generation Sequencing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment

EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib

Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping

Genomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarker

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas

Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile

Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis.

Identification of mutations in CUL7 in 3-M syndrome

Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma.

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors

Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery

Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.

Malignant neurocristic hamartoma: a tumor distinct from conventional melanoma and malignant blue nevus

Merkel cell carcinoma: 30-year experience from a single institution

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model.

Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience

Mutational analysis and clinical correlation of metastatic colorectal cancer

NRAS mutations are rare in colorectal cancer

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

Primary Benign and Malignant Thyroid Neoplasms With Signet Ring Cells: Cytologic, Histologic, and Molecular Features.

Prospective, high-throughput molecular profiling of human gliomas

Pulmonary adenocarcinoma mutation profile in smokers with smoking-related interstitial fibrosis

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

Standardized decision support in next generation sequencing reports of somatic cancer variants

Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

Tau phosphorylation sites work in concert to promote neurotoxicity in vivo

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation

The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma.

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis