Lista de obras -

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

artículo científico

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

artículo científico publicado en 2010

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

artículo científico publicado en 2011

A common variant in the Von Willebrand factor gene is associated with multiple functional consequences.

artículo científico publicado en 2010

A graphical assessment of p-values from sliding window haplotype tests of association to identify asthma susceptibility loci on chromosome 11q.

artículo científico publicado en 2006

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

artículo científico publicado en 2021

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations

artículo científico publicado en 2012

African ancestry is a risk factor for asthma and high total IgE levels in African admixed populations.

artículo científico publicado en 2013

An American Thoracic Society/National Heart, Lung, and Blood Institute workshop report: addressing respiratory health equality in the United States

journal article published in 2017

Application of the regression of offspring on mid-parent method to detect associations between single-nucleotide polymorphisms and the beta 2 electroencephalogram phenotype in the COGA data

artículo científico publicado en 2005

Aquaporin 5 polymorphisms and rate of lung function decline in chronic obstructive pulmonary disease

artículo científico publicado en 2010

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

artículo científico publicado en 2021

Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population

artículo científico publicado en 2006

Comparison of year-of-exam- and age-matched estimates of heritability in the Framingham Heart Study data

artículo científico publicado en 2003

Consistency of genetic analyses in longitudinal data: observations from the GAW13 Framingham Heart Study data

artículo científico publicado en 2003

Detectable clonal mosaicism from birth to old age and its relationship to cancer

artículo científico publicado en 2012

Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases

artículo científico publicado en 2014

Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome

artículo científico publicado en 2011

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

artículo científico publicado en 2013

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

artículo científico publicado en 2020

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

artículo científico publicado en 2015

Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects

artículo científico publicado en 2009

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

artículo científico publicado en 2016

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis ⬇️

artículo científico publicado el 8 de julio de 2012

FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population

artículo científico publicado en 2010

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans

artículo científico publicado en 2012

Gene encoding Duffy antigen/receptor for chemokines is associated with asthma and IgE in three populations

artículo científico publicado en 2008

Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake

artículo científico publicado en 2014

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2015

Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects

artículo científico publicado en 2012

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

artículo científico publicado en 2017

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene

scientific journal article

Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos

artículo científico publicado en 2014

Genome-wide association study of lung function phenotypes in a founder population

artículo científico publicado en 2013

Genome-wide interaction studies reveal sex-specific asthma risk alleles

artículo científico publicado en 2014

Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

artículo científico publicado en 2012

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes

artículo científico publicado en 2014

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1

artículo científico publicado en 2007

Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing

artículo científico publicado en 2015

Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium

artículo científico publicado en 2005

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

artículo científico publicado en 2011

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome

artículo científico publicado en 2017

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

artículo científico publicado en 2012

Independent metabolic syndrome variants predict new-onset coronary artery disease.

artículo científico publicado en 2010

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

artículo científico publicado en 2020

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

artículo científico publicado en 2014

Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene

artículo científico publicado en 2013

Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits

artículo científico publicado en 2005

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

artículo científico publicado en 2010

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

artículo científico publicado en 2016

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

artículo científico publicado en 2014

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

artículo científico publicado en 2015

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

artículo científico publicado en 2019

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

artículo científico publicado en 2014

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

artículo científico publicado en 2011

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

artículo científico publicado en 2016

On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies

artículo científico publicado en 2009

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

artículo científico publicado en 2016

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

artículo científico publicado en 2015

Resequencing candidate genes implicates rare variants in asthma susceptibility

artículo científico publicado en 2012

Sensitive detection of chromosomal segments of distinct ancestry in admixed populations

artículo científico publicado en 2009

Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability

artículo científico publicado en 2004

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

artículo científico publicado en 2019

The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions

artículo científico publicado en 2010

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

artículo científico publicado en 2011

The robustness of generalized estimating equations for association tests in extended family data

artículo científico publicado en 2012

Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster

artículo científico publicado en 2017

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

artículo científico publicado en 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

artículo científico publicado en 2019

Using genotype array data to compare multi- and single-sample variant calls and improve variant call sets from deep coverage whole-genome sequencing data

artículo científico publicado en 2016

Variants of DENND1B associated with asthma in children

artículo científico publicado en 2009

Lista de obras de

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

A common variant in the Von Willebrand factor gene is associated with multiple functional consequences.

A graphical assessment of p-values from sliding window haplotype tests of association to identify asthma susceptibility loci on chromosome 11q.

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations

African ancestry is a risk factor for asthma and high total IgE levels in African admixed populations.

An American Thoracic Society/National Heart, Lung, and Blood Institute workshop report: addressing respiratory health equality in the United States

Application of the regression of offspring on mid-parent method to detect associations between single-nucleotide polymorphisms and the beta 2 electroencephalogram phenotype in the COGA data

Aquaporin 5 polymorphisms and rate of lung function decline in chronic obstructive pulmonary disease

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population

Comparison of year-of-exam- and age-matched estimates of heritability in the Framingham Heart Study data

Consistency of genetic analyses in longitudinal data: observations from the GAW13 Framingham Heart Study data

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases

Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome

Directional dominance on stature and cognition in diverse human populations

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis ⬇️

FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans

Gene encoding Duffy antigen/receptor for chemokines is associated with asthma and IgE in three populations

Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease

Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene

Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos

Genome-wide association study of lung function phenotypes in a founder population

Genome-wide interaction studies reveal sex-specific asthma risk alleles

Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1

Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing

Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Independent metabolic syndrome variants predict new-onset coronary artery disease.

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene

Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

Resequencing candidate genes implicates rare variants in asthma susceptibility

Sensitive detection of chromosomal segments of distinct ancestry in admixed populations

Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

The robustness of generalized estimating equations for association tests in extended family data

Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Using genotype array data to compare multi- and single-sample variant calls and improve variant call sets from deep coverage whole-genome sequencing data

Variants of DENND1B associated with asthma in children