Lista de obras -

A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis

artículo científico publicado en 2016

A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells

artículo científico publicado en 2003

A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells

artículo científico publicado en 2010

Activation of innate immunity, inflammation, and potentiation of DNA vaccination through mammalian expression of the TLR5 agonist flagellin.

artículo científico publicado en 2005

An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function

artículo científico publicado en 2008

An effective serum- and xeno-free chemically defined freezing procedure for human embryonic and induced pluripotent stem cells

artículo científico publicado en 2010

Anti-VEGF agents confer survival advantages to tumor-bearing mice by improving cancer-associated systemic syndrome

artículo científico publicado en 2008

Attenuation of acute experimental colitis by preventing NPY Y1 receptor signaling

artículo científico publicado en 2004

Carotid Catheterization and Automated Blood Sampling Induce Systemic IL-6 Secretion and Local Tissue Damage and Inflammation in the Heart, Kidneys, Liver and Salivary Glands in NMRI Mice

artículo científico publicado en 2016

Development of mammary tumors by conditional expression of GLI1

scientific article published on 19 May 2009

Differential expression of A-type and B-type lamins during hair cycling

artículo científico publicado en 2009

Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.

artículo científico publicado en 2011

Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis

artículo científico publicado en 2006

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

artículo científico publicado en 2014

Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties

artículo científico publicado en 2012

Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

scientific journal article

Global and 3D spatial assessment of neuroinflammation in rodent models of Multiple Sclerosis

artículo científico publicado en 2013

Glutathione is essential for early embryogenesis – Analysis of a glutathione synthetase knockout mouse ⬇️

artículo científico publicado el 23 de julio de 2011

Hematopoiesis in the thymidine kinase 2 deficient mouse model of mitochondrial DNA depletion syndrome

artículo científico publicado en 2010

Host-pathogen interactions and the pathological consequences of acute systemic Candida albicans infections in mice.

artículo científico publicado en 2006

Human sterol 12a-hydroxylase (CYP8B1) is mainly expressed in hepatocytes in a homogenous pattern

artículo científico publicado en 2005

Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1.

artículo científico publicado en 2007

Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction

artículo científico publicado en 2003

Inhibition of the Intrinsic but Not the Extrinsic Apoptosis Pathway Accelerates and Drives Myc-Driven Tumorigenesis Towards Acute Myeloid Leukemia ⬇️

artículo científico publicado el 29 de febrero de 2012

Laminin α4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain

artículo científico publicado en 2014

Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice ⬇️

artículo científico publicado el 31 de agosto de 2011

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

scientific article published on 27 July 2009

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype

artículo científico publicado en 2005

Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model

artículo científico publicado en 2010

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene

artículo científico publicado en 2011

Organized development from human embryonic stem cells after injection into immunodeficient mice.

artículo científico publicado en 2004

Physiological and pathological impact of blood sampling by retro-bulbar sinus puncture and facial vein phlebotomy in laboratory mice.

artículo científico publicado en 2014

Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

scientific journal article

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1

artículo científico publicado en 2002

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

artículo científico publicado en 2016

Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo.

artículo científico publicado en 2015

Targeted Expression of GLI1 in the Salivary Glands Results in an Altered Differentiation Program and Hyperplasia ⬇️

artículo científico publicado el 18 de septiembre de 2011

The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice

artículo científico publicado en 2008

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

artículo científico publicado en 2012

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition

scholarly article

Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice

artículo científico publicado en 2009

Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus

artículo científico publicado en 2002

Lista de obras de

A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis

A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells

A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells

Activation of innate immunity, inflammation, and potentiation of DNA vaccination through mammalian expression of the TLR5 agonist flagellin.

An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function

An effective serum- and xeno-free chemically defined freezing procedure for human embryonic and induced pluripotent stem cells

Anti-VEGF agents confer survival advantages to tumor-bearing mice by improving cancer-associated systemic syndrome

Attenuation of acute experimental colitis by preventing NPY Y1 receptor signaling

Carotid Catheterization and Automated Blood Sampling Induce Systemic IL-6 Secretion and Local Tissue Damage and Inflammation in the Heart, Kidneys, Liver and Salivary Glands in NMRI Mice

Development of mammary tumors by conditional expression of GLI1

Differential expression of A-type and B-type lamins during hair cycling

Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.

Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties

Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

Global and 3D spatial assessment of neuroinflammation in rodent models of Multiple Sclerosis

Glutathione is essential for early embryogenesis – Analysis of a glutathione synthetase knockout mouse ⬇️

Hematopoiesis in the thymidine kinase 2 deficient mouse model of mitochondrial DNA depletion syndrome

Host-pathogen interactions and the pathological consequences of acute systemic Candida albicans infections in mice.

Human sterol 12a-hydroxylase (CYP8B1) is mainly expressed in hepatocytes in a homogenous pattern

Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1.

Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction

Inhibition of the Intrinsic but Not the Extrinsic Apoptosis Pathway Accelerates and Drives Myc-Driven Tumorigenesis Towards Acute Myeloid Leukemia ⬇️

Laminin α4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain

Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice ⬇️

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype

Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene

Organized development from human embryonic stem cells after injection into immunodeficient mice.

Physiological and pathological impact of blood sampling by retro-bulbar sinus puncture and facial vein phlebotomy in laboratory mice.

Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo.

Targeted Expression of GLI1 in the Salivary Glands Results in an Altered Differentiation Program and Hyperplasia ⬇️

The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition

Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice

Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus