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2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun NH2-terminal kinase activation

artículo científico publicado en 2006

A candidate targeting molecule of insulin-like growth factor-I receptor for gastrointestinal cancers.

artículo científico publicado en 2010

A case of Mikulicz's disease complicated by autoimmune pancreatitis, in which impaired glucose tolerance was improved by glucocorticoid treatment

artículo científico publicado en 2005

A case of Ménétrier's disease without Helicobacter pylori infection

artículo científico publicado en 2012

A case of alveolar hydatid disease of the liver for which progression was seen on CT images

artículo científico publicado en 2007

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population

scientific journal article

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

artículo científico publicado en 2009

A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer

artículo científico publicado en 2016

A new conceptualization for Mikulicz's disease as an IgG4-related plasmacytic disease

artículo científico publicado en 2006

A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors

artículo científico publicado en 2010

A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth

artículo científico publicado en 2009

A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells

artículo científico publicado en 2008

A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.

artículo científico publicado en 2009

Adult-onset Still’s disease in pregnancy

artículo científico publicado el 14 de julio de 2011

Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer

artículo científico publicado en 2012

Analysis of serum IgG subclasses in Churg-Strauss syndrome--the meaning of elevated serum levels of IgG4.

artículo científico publicado en 2010

Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy

artículo científico publicado en 2015

Antisense therapy of MAdCAM-1 for trinitrobenzenesulfonic acid-induced murine colitis

artículo científico publicado en 2006

Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer

artículo científico publicado en 2016

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.

artículo científico publicado en 2015

Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer

artículo científico publicado en 2014

Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan

artículo científico publicado en 2008

Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma.

artículo científico publicado en 2010

Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.

artículo científico publicado en 2013

Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation

artículo científico publicado en 2006

Bortezomib plus dexamethasone treatment followed by reduced-intensity allogeneic stem cell transplantation for multiple myeloma refractory to high-dose chemotherapy with autologous transplantation

artículo científico publicado el 1 de marzo de 2011

Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.

artículo científico publicado en 2013

Cancer epigenomics: implications of DNA methylation in personalized cancer therapy

artículo científico publicado en 2009

Characteristics of Japanese inflammatory bowel disease susceptibility loci

artículo científico

Clinicopathologic similarities between Mikulicz disease and Küttner tumor

artículo científico publicado en 2009

Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.

artículo científico publicado en 2015

Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer

artículo científico publicado el 20 de mayo de 2011

Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.

artículo científico publicado en 2006

Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors

artículo científico publicado en 2013

Correlation of laterally spreading type and JC virus with methylator phenotype status in colorectal adenoma

artículo científico publicado en 2008

Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer

artículo científico publicado en 2008

DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer

artículo científico publicado en 2008

DNA methylation and cancer pathways in gastrointestinal tumors

artículo científico publicado en 2008

DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae

artículo científico publicado en 2010

Detection of fecal interferon-induced transmembrane protein messenger RNA for colorectal cancer screening

artículo científico publicado en 2010

Differential expression of angiogenesis-related genes in human gastric cancers with and those without high-frequency microsatellite instability.

artículo científico publicado en 2007

Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity.

artículo científico publicado en 2009

Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.

artículo científico publicado en 2011

Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.

artículo científico publicado en 2008

Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis

artículo científico publicado en 2011

Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies

artículo científico publicado en 2009

Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors.

artículo científico publicado en 2015

Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

artículo científico publicado en 2008

Epigenetics in gastroenterological cancer and prospects for translational research.

artículo científico publicado en 2007

Establishment of a refined culture method for rat colon organoids

artículo científico publicado en 2017

Evaluation and Clinical Validity of a New Questionnaire for Mikulicz's Disease

artículo científico publicado el 8 de mayo de 2012

Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: results from the SMART database

artículo científico publicado en 2014

Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas.

artículo científico publicado en 2006

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

artículo científico publicado en 2007

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma

artículo científico publicado en 2008

Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

artículo científico publicado en 2005

Genetic and epigenetic characteristics of gastric cancers with JC virus T-antigen

artículo científico publicado en 2009

Genetic and epigenetic profiling in early colorectal tumors and prediction of invasive potential in pT1 (early invasive) colorectal cancers.

artículo científico publicado en 2006

Genetic variants in surfactant, pulmonary-associated protein D (SFTPD) and Japanese susceptibility to ulcerative colitis

artículo científico publicado en 2009

Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.

artículo científico publicado en 2009

HER2 expression and PI3K-Akt pathway alterations in gastric cancer.

artículo científico

Haploinsufficiency in multiploid colorectal cancer

artículo científico publicado en 2005

Heat stress activates ER stress signals which suppress the heat shock response, an effect occurring preferentially in the cortex in rats

scientific journal article

Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models

artículo científico publicado en 2008

Histone deacetylase inhibitors enhance phosphorylation of histone H2AX after ionizing radiation

artículo científico publicado en 2006

IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.

artículo científico publicado en 2014

IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype

artículo científico publicado en 2009

Identification of flotillin-2, a major protein on lipid rafts, as a novel target of p53 family members

artículo científico publicado en 2008

Identification of relapse predictors in IgG4-related disease using multivariate analysis of clinical data at the first visit and initial treatment.

artículo científico publicado en 2014

Insulin-like growth factor-I receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma

artículo científico publicado en 2006

Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

artículo científico publicado en 2008

Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin.

artículo científico publicado en 2009

Insulin-like growth factor-I receptor blockade reduces tumor angiogenesis and enhances the effects of bevacizumab for a human gastric cancer cell line, MKN45.

artículo científico publicado en 2011

Integrated analysis of genetic and epigenetic alterations in cancer

artículo científico publicado en 2009

Interferon gamma assay for detecting latent tuberculosis infection in rheumatoid arthritis patients during infliximab administration

artículo científico publicado en 2007

Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo

artículo científico publicado en 2011

Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer.

artículo científico

Intractable colitis associated with chronic granulomatous disease.

artículo científico publicado en 2006

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling

artículo científico publicado en 2007

LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.

artículo científico publicado en 2008

Leukoencephalopathy during administration of etanercept for refractory rheumatoid arthritis

artículo científico publicado en 2007

Loss of interleukin-21 leads to atrophic germinal centers in multicentric Castleman's disease

artículo científico publicado en 2015

Mediastinal Yolk Sac Tumor Producing Protein Induced by Vitamin K Absence or Antagonist-II.

artículo científico

Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect

artículo científico publicado en 2010

MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.

artículo científico publicado en 2014

Mikulicz's disease and systemic IgG4-related plasmacytic syndrome (SIPS).

artículo científico publicado en 2008

Molecular analysis of gastrointestinal tumor and translational research.

artículo científico publicado en 2011

Mutational analysis of beta-catenin and the RAS-RAF signalling pathway in early flat-type colorectal tumours.

artículo científico publicado en 2006

Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat.

artículo científico publicado en 2010

Necessity of early intervention for IgG4-related disease--delayed treatment induces fibrosis progression

artículo científico publicado el 19 de diciembre de 2012

Nonspecific cross-reacting antigen (NCA)--carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)

artículo científico publicado el 1 de julio de 2010

Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer

artículo científico publicado en 2007

Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth

artículo científico publicado en 2008

Overexpression of beta3/gamma2 chains of laminin-5 and MMP7 in biliary cancer.

artículo científico publicado en 2009

Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis

artículo científico publicado en 2006

Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers.

artículo científico publicado en 2008

Oxidative stress impairs the heat stress response and delays unfolded protein recovery

artículo científico publicado en 2009

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

artículo científico publicado en 2007

Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity

scientific article published on 01 December 2006

Phenotypic alteration of interstitial cells of Cajal in idiopathic sigmoid megacolon

scientific article published on 17 August 2008

Plasma analysis of rheumatoid arthritis by SELDI

artículo científico publicado en 2007

Relapse patterns in IgG4-related disease: Table 1

artículo científico publicado el 15 de mayo de 2012

Risk of malignancies in IgG4-related disease

artículo científico publicado el 6 de septiembre de 2011

Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission

artículo científico publicado en 2015

Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis.

artículo científico publicado en 2006

Seasonal allergies and serial changes of serum levels of IgG4 in cases treated with maintenance therapy for IgG4-related disease

artículo científico publicado en 2015

Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity

artículo científico publicado en 2005

Targeting for insulin-like growth factor-I receptor with short hairpin RNA for human digestive/gastrointestinal cancers

artículo científico publicado en 2009

The birthday of a new syndrome: IgG4-related diseases constitute a clinical entity

artículo científico publicado en 2010

The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.

artículo científico publicado en 2013

The effect of forced expression of mutated K-RAS gene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy.

artículo científico publicado en 2016

The efficacy of IGF-I receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status.

artículo científico publicado en 2011

The immunobiology and clinical characteristics of IgG4 related diseases

artículo científico publicado el 15 de febrero de 2012

The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway

artículo científico publicado en 2016

The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents

artículo científico publicado en 2005

The role of cytotoxic T cells in IgG4-related dacryoadenitis and sialadenitis, the so-called Mikulicz's disease

Tophaceous gout in the cervical spine

artículo científico publicado en 2012

Usefulness of measuring serum IgG4 level as diagnostic and treatment marker in IgG4-related disease

artículo científico publicado el 1 de enero de 2012

Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases

artículo científico publicado el 28 de septiembre de 2011

[A case in which the subject was affected by Listeia meningoencephalitis during administration of infliximab for steroid-dependent adult onset Still's disease].

artículo científico publicado en 2006

[A case of AFP and PIVKA-II producing gastric carcinoma]

artículo científico publicado en 2006

[A case of lupus erythematosus profundus followed by systemic lupus erythematosus presenting with severe intestinal involvement].

artículo científico publicado en 2007

[Evidence of cartilaginous benefit of treatment with infliximab in rheumatoid arthritis using measurement of serum COMP]

artículo científico publicado en 2007

[Hemorrhage from varices of an interposed jejunum after choledochojejunostomy successfully treated by transileocolic vein obliteration]

artículo científico publicado en 2008

[Long-term survival after autologous peripheral blood stem cell transplantation in a patient with primary AL amyloidosis complicating congestive heart failure]

scientific article published on 01 November 2007

[The significance of disease-independence in Mikulicz's disease--revival interests in Mikulicz's disease]

scientific article published on 01 February 2006

p53 family members regulate the expression of the apolipoprotein D gene.

artículo científico publicado en 2008