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A full genome search in multiple sclerosis

article

A retrospective claims analysis: Compliance and discontinuation rates among Canadian patients with multiple sclerosis treated with disease-modifying therapies

artículo científico publicado en 2019

Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers

scientific article published on 01 November 2019

Anti-JC Virus Antibody Prevalence in Canadian MS Patients

artículo científico publicado en 2014

Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS.

artículo científico publicado en 2017

Assessing the risk of multiple sclerosis disease-modifying therapies

artículo científico publicado en 2019

Assessment of social cognition in patients with multiple sclerosis.

artículo científico publicado en 2010

Association of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis

artículo científico publicado en 2018

Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

scientific article published on 01 January 2019

Association of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis

scientific article published on 27 July 2020

Association of multiple sclerosis susceptibility variants and early attack location in the CNS

artículo científico publicado en 2013

B cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients

artículo científico publicado en 2011

Balancing Early Aggression Against Risk of Progression in Multiple Sclerosis

artículo científico publicado en 2015

Brain, cognition and MRI in MS: an ongoing refinement process ⬇️

artículo científico publicado el 1 de septiembre de 2010

CD70 defines a subset of proinflammatory and CNS-pathogenic TH1/TH17 lymphocytes and is overexpressed in multiple sclerosis

scientific article published on 11 January 2019

Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin

artículo científico publicado en 2011

Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis.

artículo científico publicado en 2017

Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis

artículo científico publicado en 2018

Comparative effectiveness of glatiramer acetate and interferon beta formulations in relapsing-remitting multiple sclerosis

artículo científico publicado en 2014

Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS.

artículo científico publicado en 2016

Comparative efficacy of switching to natalizumab in active multiple sclerosis

artículo científico publicado en 2015

Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis

scientific article published on 13 January 2019

Comparison of switch to fingolimod or interferon beta/glatiramer acetate in active multiple sclerosis

artículo científico publicado en 2015

Contribution of different relapse phenotypes to disability in multiple sclerosis.

artículo científico publicado en 2016

Contribution of symptom clusters to multiple sclerosis consequences

artículo científico publicado en 2014

Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis.

artículo científico publicado en 2013

Deaths and disability from natalizumab are no longer tolerable: Yes

artículo científico publicado en 2012

Defining reliable disability outcomes in multiple sclerosis.

artículo científico publicado en 2015

Defining secondary progressive multiple sclerosis

artículo científico publicado en 2016

Detecting subtle cognitive impairment in multiple sclerosis with the MoCA test

artículo científico publicado en 2020

Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis

artículo científico publicado en 2020

Discontinuing disease-modifying therapy in MS after a prolonged relapse-free period: a propensity score-matched study

artículo científico publicado en 2016

Does pain in individuals with multiple sclerosis affect employment? A systematic review and meta-analysis

scientific article published on September 2013

Does pregnancy alter the long-term course of multiple sclerosis?

artículo científico publicado en 2014

Early clinical markers of aggressive multiple sclerosis

scientific article published on 09 May 2020

Effect of Disease Modifying Therapy on Disability in Relapsing-Remitting Multiple Sclerosis Over 15 Years

scientific article published on 28 December 2020

Effect of continuous positive airway pressure treatment of obstructive sleep apnea-hypopnea in multiple sclerosis: A randomized, double-blind, placebo-controlled trial (SAMS-PAP study)

artículo científico publicado en 2021

Evolving role of MRI in optimizing the treatment of multiple sclerosis: Canadian Consensus recommendations.

artículo científico publicado en 2015

Exercise barriers and preferences among women and men with multiple sclerosis

artículo científico publicado en 2013

Factors associated with delay to medical recognition in two Canadian multiple sclerosis cohorts

article

Fingolimod after natalizumab and the risk of short-term relapse

artículo científico publicado en 2014

Frailty in ageing persons with multiple sclerosis

scientific article published on 27 May 2020

Gender Issues in Multiple Sclerosis: An Update ⬇️

artículo científico publicado el 1 de noviembre de 2010

Geographical variations in sex ratio trends over time in multiple sclerosis.

artículo científico publicado en 2012

Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis.

artículo científico publicado en 2016

Highly active immunomodulatory therapy ameliorates accumulation of disability in moderately advanced and advanced multiple sclerosis

artículo científico publicado en 2016

Historical changes of seasonal differences in the frequency of multiple sclerosis clinical attacks: a multicenter study

artículo científico publicado en 2012

How safe is natalizumab during pregnancy?

scientific article published on 12 November 2014

IM interferon beta-1a delays definite multiple sclerosis 5 years after a first demyelinating event

scientific article published on 25 January 2006

Impairment, disability and fatigue in multiple sclerosis

artículo científico publicado en 2018

Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study

scientific article published on 03 January 2019

Increased frequency of restless legs syndrome in a French-Canadian population with multiple sclerosis

scientific article published on 01 November 2005

Increasing age at disability milestones among MS patients in the MSBase Registry

artículo científico

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

article

Inhibition of glyceraldehyde-3-phosphate dehydrogenase activity by antibodies present in the cerebrospinal fluid of patients with multiple sclerosis

artículo científico publicado en 2010

Interferons in MS Treatment: report from the Canadian MS Forum symposium, 26-29 August 2004, Québec, Canada

scientific article published on 01 April 2005

Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE

scientific article published on 15 December 2020

Interleukin-26, preferentially produced by TH17 lymphocytes, regulates CNS barrier function

artículo científico publicado en 2020

Intrathecal B-cell clonal expansion, an early sign of humoral immunity, in the cerebrospinal fluid of patients with clinically isolated syndrome suggestive of multiple sclerosis

artículo científico publicado en 2003

Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis

artículo científico publicado en 2017

Long-term human coronavirus-myelin cross-reactive T-cell clones derived from multiple sclerosis patients

scientific article published on 19 April 2007

MS, MRI, and the 2010 McDonald criteria: a Canadian expert commentary

artículo científico publicado en 2012

Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS

artículo científico publicado en 2015

Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system.

artículo científico publicado en 2012

Melanoma cell adhesion molecule-positive CD8 T lymphocytes mediate central nervous system inflammation.

artículo científico publicado en 2015

Migration of multiple sclerosis lymphocytes through brain endothelium

artículo científico publicado en 2002

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

artículo científico publicado en 2004

Multiple sclerosis and pregnancy: a comparison study

artículo científico publicado en 2013

Multiple sclerosis in Latin America: A different disease course severity? A collaborative study from the MSBase Registry

artículo científico publicado en 2015

Multiple sclerosis susceptibility genes: associations with relapse severity and recovery

artículo científico publicado en 2013

Mutations in the hemochromatosis gene and the clinical outcome of multiple sclerosis

article

Pain acts through fatigue to affect participation in individuals with multiple sclerosis

artículo científico publicado en 2015

Participation in and outcomes from a 12-month tailored exercise programme for people with multiple sclerosis (MSTEP©): a randomized trial

scientific article published on 21 May 2020

Path to Illness Intrusiveness: What Symptoms Affect the Life of People Living With Multiple Sclerosis?

artículo científico publicado en 2017

Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis

artículo científico publicado en 2013

Predictors and dynamics of postpartum relapses in women with multiple sclerosis.

artículo científico publicado en 2013

Predictors of disability worsening in clinically isolated syndrome.

artículo científico publicado en 2015

Predictors of long-term disability accrual in relapse-onset multiple sclerosis

artículo científico publicado en 2016

Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy

Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis.

artículo científico publicado en 2009

Prognostic indicators in pediatric clinically isolated syndrome

artículo científico publicado en 2017

Prospective memory impairment in multiple sclerosis: a review

artículo científico publicado en 2017

Prospective memory in multiple sclerosis: The impact of cue distinctiveness and executive functioning

artículo científico publicado en 2016

Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice.

artículo científico publicado en 2016

Risk of relapse phenotype recurrence in multiple sclerosis.

artículo científico publicado en 2014

Risk of secondary progressive multiple sclerosis: A longitudinal study

scientific article published on 09 August 2019

Role of executive functions in prospective memory in multiple sclerosis: Impact of the strength of cue-action association

artículo científico publicado en 2015

Seasonal variation of relapse rate in multiple sclerosis is latitude dependent.

artículo científico publicado en 2014

Sex as a determinant of relapse incidence and progressive course of multiple sclerosis

artículo científico publicado en 2013

Silent lesions on MRI imaging - Shifting goal posts for treatment decisions in multiple sclerosis

scientific article published on 20 September 2018

Sleep disorders in patients with multiple sclerosis.

artículo científico publicado en 2009

Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis

artículo científico publicado en 2006

Switch to natalizumab versus fingolimod in active relapsing-remitting multiple sclerosis.

artículo científico publicado en 2015

Thalamic and hippocampal volume associated with memory functions in multiple sclerosis

artículo científico publicado en 2018

The IL-27/IL-27R axis is altered in CD4<sup>+</sup> and CD8<sup>+</sup> T lymphocytes from multiple sclerosis patients

artículo científico publicado en 2021

The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry

The effect of oral immunomodulatory therapy on treatment uptake and persistence in multiple sclerosis

artículo científico publicado en 2015

The impact of treatment adherence on clinical and economic outcomes in multiple sclerosis: Real world evidence from Alberta, Canada

artículo científico publicado en 2017

The role of exercise in modifying outcomes for people with multiple sclerosis: a randomized trial

artículo científico publicado en 2013

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study

artículo científico publicado en 2020

Towards personalized therapy for multiple sclerosis: prediction of individual treatment response.

artículo científico publicado en 2017

Trajectory of MS disease course for men and women over three eras

artículo científico publicado en 2016

Treatment Optimization in Multiple Sclerosis: Canadian MS Working Group Recommendations

scientific article published on 06 April 2020

Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study.

artículo científico publicado en 2017

Treatment response score to glatiramer acetate or interferon beta-1a

artículo científico publicado en 2020

Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis.

artículo científico publicado en 2017

Value of the MoCA test as a screening instrument in multiple sclerosis.

artículo científico publicado en 2013

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