Lista de obras -

624. Microbiota and Associations with Treatment Outcome in Fecal Microbiota Transplantation

scholarly article by Tatiana Bogdanovich et al published November 2018 in Open Forum Infectious Diseases

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides

scientific article published on 13 July 2009

Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

artículo científico publicado en 2013

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

artículo científico publicado en 2007

Competitive fitness assays indicate that the E138A substitution in HIV-1 reverse transcriptase decreases in vitro susceptibility to emtricitabine

artículo científico publicado en 2014

Conformational Changes in HIV-1 Reverse Transcriptase that Facilitate Its Maturation

scientific article published on 27 August 2019

Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding

artículo científico publicado en 2004

Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors

artículo científico publicado en 2002

Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1.

artículo científico publicado en 2014

Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog ⬇️

artículo científico publicado el 14 de enero de 2013

E138A in HIV-1 reverse transcriptase is more common in subtype C than B: implications for rilpivirine use in resource-limited settings

artículo científico publicado en 2014

Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision

artículo científico publicado en 2007

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

artículo científico publicado en 2005

Effect of Reverse Transcriptase Inhibitors and Mutations on the Low-Cost Cavidi Reverse Transcriptase Viral Load Assay

artículo científico publicado en 2009

Efficient HIV-1 Trans Infection of CD4+ T Cells Occurs in the Presence of Antiretroviral Therapy

scientific article published on 24 May 2019

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

artículo científico publicado en 2016

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

artículo científico publicado en 2013

Failure of Initial Therapy With Two Nucleosides and Efavirenz Is Not Associated With Early Emergence of Mutations in the C-Terminus of HIV-1 Reverse Transcriptase ⬇️

artículo científico publicado el 1 de abril de 2011

Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors

artículo científico publicado en 2012

Future of nonnucleoside reverse transcriptase inhibitors

artículo científico publicado en 2018

Glutathione-S-transferase FosA6 of Klebsiella pneumoniae origin conferring fosfomycin resistance in ESBL-producing Escherichia coli.

artículo científico publicado en 2016

High-Level Fosfomycin Resistance in Vancomycin-Resistant Enterococcus faecium.

artículo científico publicado en 2017

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

artículo científico publicado en 2015

Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability

artículo científico publicado en 2008

In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine, and MIV-150, Nonnucleoside Reverse Transcriptase Inhibitor Microbicides in Clinical Development for the Prevention of HIV-1 Infection

artículo científico publicado en 2017

In vitro characterization of a sustained-release formulation for enfuvirtide.

artículo científico publicado en 2013

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

artículo científico publicado en 2016

Inhibition of fosfomycin resistance protein FosA by phosphonoformate (foscarnet) in multidrug-resistant Gram-negative pathogens.

artículo científico publicado en 2017

Inhibitors of Signaling Pathways That Block Reversal of HIV-1 Latency

artículo científico publicado en 2019

Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells

artículo científico publicado en 2011

Large Multidomain Protein NMR: HIV-1 Reverse Transcriptase Precursor in Solution

scientific article published on 15 December 2020

Mechanism by which a glutamine to leucine substitution at residue 509 in the ribonuclease H domain of HIV-1 reverse transcriptase confers zidovudine resistance

artículo científico publicado en 2008

Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence

artículo científico publicado en 2014

Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine

artículo científico publicado en 2007

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

artículo científico publicado en 2008

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules

artículo científico publicado en 2002

Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors

artículo científico publicado en 2006

Molecular mechanism of HIV-1 resistance to 3'-azido-2',3'-dideoxyguanosine

artículo científico publicado en 2013

Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase

artículo científico publicado en 2007

Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones

artículo científico publicado en 2001

N348I in HIV-1 reverse transcriptase counteracts the synergy between zidovudine and nevirapine

artículo científico publicado en 2012

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations

artículo científico publicado en 2010

N348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutations

artículo científico publicado en 2010

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

artículo científico publicado en 2007

Naive CD4+ T Cells Harbor a Large Inducible Reservoir of Latent, Replication-competent Human Immunodeficiency Virus Type 1

artículo científico publicado en 2019

Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase

artículo científico publicado en 2019

Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Production from Latently Infected Resting CD4+ T Cells following Latency Reversal.

artículo científico publicado en 2016

Novel N-3 substituted TSAO-T derivatives: synthesis and anti-HIV-evaluation.

artículo científico publicado en 2008

Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells.

artículo científico publicado en 2017

Novel high-throughput screen identifies an HIV-1 reverse transcriptase inhibitor with a unique mechanism of action

artículo científico publicado en 2014

Origin of the plasmid-mediated fosfomycin resistance gene fosA3.

artículo científico publicado en 2017

Peptides Mimicking the β7/β8 Loop of HIV-1 Reverse Transcriptase p51 as "Hotspot-Targeted" Dimerization Inhibitors

scientific article published on 24 January 2020

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

artículo científico publicado en 2006

Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses

artículo científico publicado en 2007

Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation

artículo científico publicado en 2004

Radiation target analyses of DNA template/primer complexes

artículo científico publicado en 2006

Replication fitness of multiple nonnucleoside reverse transcriptase-resistant HIV-1 variants in the presence of etravirine measured by 454 deep sequencing

artículo científico publicado en 2013

Resistance to reverse transcriptase inhibitors used in the treatment and prevention of HIV-1 infection

artículo científico publicado en 2015

Role of RNase H Activity in NRTI/NNRTI Drug Resistance

Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.

artículo científico publicado en 2007

Silent mutations are selected in HIV-1 reverse transcriptase and affect enzymatic efficiency.

artículo científico publicado en 2008

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

artículo científico publicado en 2015

Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens

scientific article published on 26 February 2019

Stereo-selectivity of HIV-1 reverse transcriptase toward isomers of thymidine-5'-O-1-thiotriphosphate

artículo científico publicado en 2005

Structural basis of reduced susceptibility to ceftazidime-avibactam and cefiderocol in Enterobacter cloacae due to AmpC R2 loop deletion

scientific article published on 13 April 2020

Structure and dynamics of FosA-mediated fosfomycin resistance in Klebsiella pneumoniae and Escherichia coli.

artículo científico publicado en 2017

Structure-activity relationships in HIV-1 reverse transcriptase revealed by radiation target analysis

artículo científico publicado en 2003

Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization.

artículo científico publicado en 2006

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs ⬇️

artículo científico publicado el 13 de septiembre de 2011

Subunit-specific mutational analysis of residue N348 in HIV-1 reverse transcriptase ⬇️

artículo científico publicado el 22 de agosto de 2011

Synthesis and Anti-HIV Evaluation of 3′-Triazolo Nucleosides ⬇️

artículo científico publicado el 1 de abril de 2011

Synthesis and Anti-HIV-1 Activity of a Novel Series of Aminoimidazole Analogs

artículo científico publicado en 2010

Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus

artículo científico publicado en 2009

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides ⬇️

artículo científico publicado el 30 de mayo de 2011

Temporal transcriptional response to latency reversing agents identifies specific factors regulating HIV-1 viral transcriptional switch

artículo científico publicado en 2015

The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1.

artículo científico publicado en 2005

The Base Component of 3′-Azido-2′,3′-Dideoxynucleosides Influences Resistance Mutations Selected in HIV-1 Reverse Transcriptase ⬇️

artículo científico publicado el 6 de junio de 2011

The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro

artículo científico publicado en 2010

The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization

artículo científico publicado en 2010

The emerging profile of cross-resistance among the nonnucleoside HIV-1 reverse transcriptase inhibitors

artículo científico publicado en 2014

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs

artículo científico publicado en 2009

Therapeutic Approaches to Eradicate Latent HIV-1 in Resting CD4+ T Cells

artículo científico

Transient kinetic analyses of the ribonuclease H cleavage activity of HIV-1 reverse transcriptase in complex with efavirenz and/or a β-thujaplicinol analogue ⬇️

artículo científico publicado el 15 de octubre de 2013

Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1.

artículo científico publicado en 2019

Widespread Fosfomycin Resistance in Gram-Negative Bacteria Attributable to the Chromosomal fosA Gene

artículo científico publicado en 2017

Zidovudine (AZT) Monotherapy Selects for the A360V Mutation in the Connection Domain of HIV-1 Reverse Transcriptase ⬇️

artículo científico publicado el 21 de febrero de 2012

Lista de obras de

624. Microbiota and Associations with Treatment Outcome in Fecal Microbiota Transplantation

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides

Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

Competitive fitness assays indicate that the E138A substitution in HIV-1 reverse transcriptase decreases in vitro susceptibility to emtricitabine

Conformational Changes in HIV-1 Reverse Transcriptase that Facilitate Its Maturation

Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding

Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors

Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1.

Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog ⬇️

E138A in HIV-1 reverse transcriptase is more common in subtype C than B: implications for rilpivirine use in resource-limited settings

Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

Effect of Reverse Transcriptase Inhibitors and Mutations on the Low-Cost Cavidi Reverse Transcriptase Viral Load Assay

Efficient HIV-1 Trans Infection of CD4+ T Cells Occurs in the Presence of Antiretroviral Therapy

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

Failure of Initial Therapy With Two Nucleosides and Efavirenz Is Not Associated With Early Emergence of Mutations in the C-Terminus of HIV-1 Reverse Transcriptase ⬇️

Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors

Future of nonnucleoside reverse transcriptase inhibitors

Glutathione-S-transferase FosA6 of Klebsiella pneumoniae origin conferring fosfomycin resistance in ESBL-producing Escherichia coli.

High-Level Fosfomycin Resistance in Vancomycin-Resistant Enterococcus faecium.

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability

In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine, and MIV-150, Nonnucleoside Reverse Transcriptase Inhibitor Microbicides in Clinical Development for the Prevention of HIV-1 Infection

In vitro characterization of a sustained-release formulation for enfuvirtide.

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

Inhibition of fosfomycin resistance protein FosA by phosphonoformate (foscarnet) in multidrug-resistant Gram-negative pathogens.

Inhibitors of Signaling Pathways That Block Reversal of HIV-1 Latency

Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells

Large Multidomain Protein NMR: HIV-1 Reverse Transcriptase Precursor in Solution

Mechanism by which a glutamine to leucine substitution at residue 509 in the ribonuclease H domain of HIV-1 reverse transcriptase confers zidovudine resistance

Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence

Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules

Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors

Molecular mechanism of HIV-1 resistance to 3'-azido-2',3'-dideoxyguanosine

Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase

Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones

N348I in HIV-1 reverse transcriptase counteracts the synergy between zidovudine and nevirapine

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations

N348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutations

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

Naive CD4+ T Cells Harbor a Large Inducible Reservoir of Latent, Replication-competent Human Immunodeficiency Virus Type 1

Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase

Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Production from Latently Infected Resting CD4+ T Cells following Latency Reversal.

Novel N-3 substituted TSAO-T derivatives: synthesis and anti-HIV-evaluation.

Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells.

Novel high-throughput screen identifies an HIV-1 reverse transcriptase inhibitor with a unique mechanism of action

Origin of the plasmid-mediated fosfomycin resistance gene fosA3.

Peptides Mimicking the β7/β8 Loop of HIV-1 Reverse Transcriptase p51 as "Hotspot-Targeted" Dimerization Inhibitors

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses

Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation

Radiation target analyses of DNA template/primer complexes

Replication fitness of multiple nonnucleoside reverse transcriptase-resistant HIV-1 variants in the presence of etravirine measured by 454 deep sequencing

Resistance to reverse transcriptase inhibitors used in the treatment and prevention of HIV-1 infection

Role of RNase H Activity in NRTI/NNRTI Drug Resistance

Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.

Silent mutations are selected in HIV-1 reverse transcriptase and affect enzymatic efficiency.

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens

Stereo-selectivity of HIV-1 reverse transcriptase toward isomers of thymidine-5'-O-1-thiotriphosphate

Structural basis of reduced susceptibility to ceftazidime-avibactam and cefiderocol in Enterobacter cloacae due to AmpC R2 loop deletion

Structure and dynamics of FosA-mediated fosfomycin resistance in Klebsiella pneumoniae and Escherichia coli.

Structure-activity relationships in HIV-1 reverse transcriptase revealed by radiation target analysis

Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization.

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs ⬇️

Subunit-specific mutational analysis of residue N348 in HIV-1 reverse transcriptase ⬇️

Synthesis and Anti-HIV Evaluation of 3′-Triazolo Nucleosides ⬇️

Synthesis and Anti-HIV-1 Activity of a Novel Series of Aminoimidazole Analogs

Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides ⬇️

Temporal transcriptional response to latency reversing agents identifies specific factors regulating HIV-1 viral transcriptional switch

The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1.

The Base Component of 3′-Azido-2′,3′-Dideoxynucleosides Influences Resistance Mutations Selected in HIV-1 Reverse Transcriptase ⬇️

The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro

The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization