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A molecular mucosal adjuvant to enhance immunity against pneumococcal infection in the elderly

artículo científico publicado en 2015

Antibody-independent, CD4+ T-cell-dependent protection against pneumococcal colonization elicited by intranasal immunization with purified pneumococcal proteins

artículo científico publicado en 2007

Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae

artículo científico publicado en 2003

CCL5-independent helper T lymphocyte responses to immuno-dominant pneumococcal surface protein A epitopes

artículo científico publicado el 14 de diciembre de 2011

Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence

artículo científico publicado en 2010

Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model.

artículo científico publicado en 2007

Decrease in penicillin susceptibility due to heat shock protein ClpL in Streptococcus pneumoniae.

artículo científico publicado en 2011

Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae.

artículo científico publicado en 2006

Development of antibodies to PspA families 1 and 2 in children after exposure to Streptococcus pneumoniae

artículo científico publicado en 2008

Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage

artículo científico publicado en 2005

Distribution of pneumococcal surface protein A families 1 and 2 among Streptococcus pneumoniae isolates from children in finland who had acute otitis media or were nasopharyngeal carriers

artículo científico publicado en 2008

Effect of apolactoferrin on experimental pneumococcal otitis media

artículo científico publicado en 2010

Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1.

artículo científico publicado en 2010

Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface

artículo científico publicado en 2004

Effects of zinc deficiency and pneumococcal surface protein a immunization on zinc status and the risk of severe infection in mice

artículo científico publicado en 2003

Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae

artículo científico publicado en 2010

Ethanol-induced alcohol dehydrogenase E (AdhE) potentiates pneumolysin in Streptococcus pneumoniae.

artículo científico publicado en 2014

Evaluation of a vaccine formulation against Streptococcus pneumoniae based on choline-binding proteins

artículo científico publicado en 2014

Evolution and virulence of serogroup 6 pneumococci on a global scale

artículo científico publicado en 2002

Exposure of Thomsen-Friedenreich antigen in Streptococcus pneumoniae infection is dependent on pneumococcal neuraminidase A

artículo científico publicado el 4 de marzo de 2011

Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.

artículo científico publicado en 2010

Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection

artículo científico publicado en 2010

Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12.

artículo científico publicado en 2003

Mapping of epitopes recognized by antibodies induced by immunization of mice with PspA and PspC.

artículo científico publicado en 2014

Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring

artículo científico publicado en 2011

Mn2+-dependent regulation of multiple genes in Streptococcus pneumoniae through PsaR and the resultant impact on virulence

artículo científico publicado en 2006

Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin

artículo científico publicado en 2014

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection

artículo científico publicado en 2015

Nontypeable pneumococci can be divided into multiple cps types, including one type expressing the novel gene pspK

artículo científico publicado en 2012

Pneumococcal carriage results in ganglioside-mediated olfactory tissue infection

artículo científico publicado el 10 de noviembre de 2003

Protection of the elderly from pneumococcal pneumonia with a protein-based vaccine?

artículo científico publicado en 2004

PspA Family Distribution, Antimicrobial Resistance and Serotype of Streptococcus pneumoniae Isolated from Upper Respiratory Tract Infections in Japan

artículo científico publicado el 6 de marzo de 2013

PspA Family Distribution, unlike Capsular Serotype, Remains Unaltered following Introduction of the Heptavalent Pneumococcal Conjugate Vaccine

artículo científico publicado el 25 de abril de 2012

PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation

artículo científico publicado en 2007

Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model

artículo científico publicado en 2003

Relative fitness of fluoroquinolone-resistant Streptococcus pneumoniae

artículo científico publicado en 2005

Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae

artículo científico publicado en 2003

Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae

artículo científico publicado en 2002

Serine Protease PrtA from Streptococcus pneumoniae Plays a Role in the Killing of S. pneumoniae by Apolactoferrin

artículo científico publicado el 21 de marzo de 2011

Serum antibodies to pneumococcal neuraminidase NanA in relation to pneumococcal carriage and acute otitis media

artículo científico publicado en 2006

Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice

artículo científico publicado en 2012

Streptococcus pneumoniae isolates from middle ear fluid and nasopharynx of children with acute otitis media exhibit phase variation

artículo científico publicado en 2011

Structure of a complex of human lactoferrin N-lobe with pneumococcal surface protein a provides insight into microbial defense mechanism

artículo científico publicado en 2007

The Effects of CFTR and Mucoid Phenotype on Susceptibility and Innate Immune Responses in a Mouse Model of Pneumococcal Lung Disease.

artículo científico publicado en 2015

The Nasal Dendritic Cell-Targeting Flt3 Ligand as a Safe Adjuvant Elicits Effective Protection against Fatal Pneumococcal Pneumonia

artículo científico publicado el 2 de mayo de 2011