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A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate

artículo científico publicado en 2008

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

artículo científico publicado en 2002

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

artículo científico publicado en 1998

A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry

artículo científico publicado en 2002

A multi-marker approach to predict incident CKD and microalbuminuria

artículo científico publicado en 2010

A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk

scientific article published on 01 September 1999

A prospective birth cohort study on cord blood folate subtypes and risk of autism spectrum disorder

scientific article published on 25 August 2020

A prospective study of folate and vitamin B6 and risk of myocardial infarction in US physicians

scientific article published on 01 April 1996

A prospective study of one-carbon metabolism biomarkers and risk of renal cell carcinoma

artículo científico publicado en 2010

A prospective study of plasma total cysteine and risk of breast cancer.

artículo científico publicado en 2003

A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer

artículo científico publicado en 1999

A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma

artículo científico publicado en 2009

A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis

artículo científico publicado en 2007

Abnormal homocysteine metabolism in rheumatoid arthritis

scientific article published on 01 April 1997

Abnormal vitamin B(6) status is associated with severity of symptoms in patients with rheumatoid arthritis

artículo científico publicado en 2003

Abnormal vitamin b6status in rheumatoid cachexia association with spontaneous tumor necrosis factor α production and markers of inflammation

artículo científico publicado en 1995

Abstract 4301: Serum vitamin B12 and development of non-cardia gastric cancer: a prospective study

article

Age and Gender Affect the Relation between Methylenetetrahydrofolate Reductase C677T Genotype and Fasting Plasma Homocysteine Concentrations in the Framingham Offspring Study Cohort ⬇️

artículo científico publicado el 1 de noviembre de 2003

Alcohol dehydrogenase 3 genotype is not predictive for risk of colorectal cancer.

artículo científico publicado en 2001

Analysis of factors influencing the comparison of homocysteine values between the Third National Health and Nutrition Examination Survey (NHANES) and NHANES 1999+.

artículo científico publicado en 2000

Analysis of folates using combined affinity and ion-pair chromatography

scientific article published on 01 January 1997

Analysis of sequential events in intestinal absorption of folylpolyglutamate

artículo científico publicado en 1988

Antifolate actions of sulfasalazine on intact lymphocytes

artículo científico publicado el 1 de junio de 1981

Are dietary choline and betaine intakes determinants of total homocysteine concentration?

artículo científico publicado en 2010

Arsenic is associated with reduced effect of folic acid in myelomeningocele prevention: a case control study in Bangladesh

artículo científico publicado en 2015

Assay of folylpolyglutamate hydrolase using pteroyl-labeled substrates and selective short-term bacterial uptake for product determination

artículo científico publicado en 1980

Association Between Folate Metabolites and the Development of Food Allergy in Children

scientific article published on 25 June 2019

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk

artículo científico publicado en 2002

Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study

artículo científico publicado en 2006

Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status

artículo científico publicado en 2003

Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population

artículo científico publicado en 1999

Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia

artículo científico publicado en 2001

Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study

artículo científico publicado en 2008

Association of plasma vitamin B6 with risk of colorectal adenoma in a multiethnic case–control study ⬇️

artículo científico publicado el 25 de marzo de 2011

Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older men.

artículo científico publicado en 2001

Associations between genes in the one-carbon metabolism pathway and advanced colorectal adenoma risk in individuals with low folate intake

artículo científico publicado en 2012

Associations between post translational histone modifications, myelomeningocele risk, environmental arsenic exposure, and folate deficiency among participants in a case control study in Bangladesh

artículo científico publicado en 2017

Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study

artículo científico publicado en 2007

Autoantibodies to folate receptors in the cerebral folate deficiency syndrome.

artículo científico publicado en 2005

B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica

artículo científico publicado en 2003

B vitamins and the aging brain ⬇️

artículo científico publicado el 1 de diciembre de 2010

B vitamins, homocysteine, and neurocognitive function in the elderly

artículo científico publicado en 2000

B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial

artículo científico publicado en 2017

B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice

artículo científico publicado en 2008

Bacterial Folates Provide an Exogenous Signal for C. elegans Germline Stem Cell Proliferation

artículo científico publicado en 2016

Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates

artículo científico publicado en 1991

Baseline characteristics of participants in the Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) Trial

artículo científico publicado en 2008

Biomarkers of folate status in NHANES: a roundtable summary

artículo científico publicado en 2011

Biomarkers of vitamin B-12 status in NHANES: a roundtable summary

artículo científico publicado en 2011

Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial

artículo científico publicado en 2004

C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study

artículo científico publicado en 2008

C-reactive protein as a predictor of total arteriosclerotic outcomes in type 2 diabetic nephropathy

artículo científico publicado en 2005

Carrier affinity as a mechanism for the pH-dependence of folate transport in the small intestine

artículo científico publicado en 1990

Case-control study of plasma folate, homocysteine, vitamin B(12), and cysteine as markers of cervical dysplasia

artículo científico publicado en 2000

Chronic diuretic therapy with moderate doses of triamterene is not associated with folate deficiency

artículo científico publicado en 1991

Chronic renal transplantation: a model for the hyperhomocysteinemia of renal insufficiency

artículo científico publicado en 2001

Circulating folic acid in plasma: relation to folic acid fortification

artículo científico publicado en 2008

Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.

artículo científico publicado en 2010

Clinical and nutritional correlates of C-reactive protein in type 2 diabetic nephropathy

artículo científico publicado en 2004

Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT).

artículo científico publicado en 2011

Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.

artículo científico publicado en 2008

Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation.

artículo científico publicado en 2003

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

artículo científico publicado en 2013

Common variants of FUT2 are associated with plasma vitamin B12 levels

artículo científico publicado en 2008

Competitive inhibition of folate absorption by dihydrofolate reductase inhibitors, trimethoprim and pyrimethamine

artículo científico publicado en 1987

Competitive inhibition of folic acid absorption in rat jejunum by triamterene

artículo científico publicado en 1986

Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients

artículo científico publicado en 2000

Conversion of 5-formyltetrahydrofolic acid to 5-methyltetrahydrofolic acid is unimpaired in folate-adequate persons homozygous for the C677T mutation in the methylenetetrahydrofolate reductase gene

artículo científico publicado en 2000

Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease.

artículo científico publicado en 1997

Correspondence: will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm?

artículo científico publicado en 2008

Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community

artículo científico publicado en 2009

Cystatin C as a determinant of fasting plasma total homocysteine levels in coronary artery disease patients with normal serum creatinine

artículo científico publicado en 1999

Decision on folic acid fortification in Europe must consider both risks and benefits

artículo científico publicado en 2016

Demonstration of high-affinity folate binding activity associated with the brush border membranes of rat kidney ⬇️

artículo científico publicado el 1 de julio de 1978

Depression and folate status in the US Population

artículo científico publicado en 2003

Determinants of fasting plasma total homocysteine levels among chronic stable renal transplant recipients

artículo científico publicado en 1999

Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort

artículo científico publicado en 2001

Determinants of plasma total homocysteine levels in Korean chronic renal transplant recipients.

artículo científico publicado en 2000

Determination of unmetabolized folic acid in human plasma using affinity HPLC.

artículo científico publicado en 2011

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

artículo científico publicado en 2005

Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc1638N Mice

artículo científico publicado en 2015

Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study

artículo científico publicado en 2006

Dietary intake pattern relates to plasma folate and homocysteine concentrations in the Framingham Heart Study

artículo científico publicado en 1996

Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease

artículo científico publicado en 2013

Dihydrofolate reductase 19-bp deletion polymorphism modifies the association of folate status with memory in a cross-sectional multi-ethnic study of adults

artículo científico publicado en 2015

Distribution of plasma folate forms in hemodialysis patients receiving high daily doses of L-folinic or folic acid

artículo científico publicado en 2002

Effect of anions on folate binding by isolated brush border membranes from rat kidney ⬇️

artículo científico publicado el 2 de noviembre de 1979

Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma

artículo científico publicado en 2012

Effect of dietary patterns on serum homocysteine: results of a randomized, controlled feeding study

artículo científico publicado en 2000

Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.

artículo científico publicado en 2003

Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice.

artículo científico publicado en 2005

Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.

artículo científico publicado en 2003

Elevated fasting total plasma homocysteine levels and cardiovascular disease outcomes in maintenance dialysis patients. A prospective study

artículo científico publicado en 1997

Elevated serum methylmalonic acid concentrations are common among elderly Americans

artículo científico publicado en 2002

Elevations in total plasma homocysteine in premature coronary artery, cerebrovascular and peripheral vascular disease

artículo científico publicado en 1993

Enhanced reduction of fasting total homocysteine levels with supraphysiological versus standard multivitamin dose folic acid supplementation in renal transplant recipients

artículo científico publicado en 1999

Enhancement of folates in plants through metabolic engineering

scholarly article

Erratum to: Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet

article

Evidence from a Randomized Trial That Exposure to Supplemental Folic Acid at Recommended Levels during Pregnancy Does Not Lead to Increased Unmetabolized Folic Acid Concentrations in Maternal or Cord Blood.

artículo científico publicado en 2016

Excess Prevalence of Fasting and Postmethionine-Loading Hyperhomocysteinemia in Stable Renal Transplant Recipients ⬇️

artículo científico publicado el 1 de octubre de 1997

Excessive folic acid intake and relation to adverse health outcome

artículo científico publicado en 2016

FMN phosphatase and FAD pyrophosphatase in rat intestinal brush borders: role in intestinal absorption of dietary riboflavin

artículo científico publicado en 1982

Family history and premature coronary heart disease.

artículo científico publicado en 1996

Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring study

artículo científico publicado en 2001

Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification

artículo científico publicado en 2007

Folate binding in intestinal brush border membranes: evidence for the presence of two binding activities

artículo científico publicado en 1990

Folate binding protein from kidney brush border membranes contains components characteristic of a glycoinositol phospholipid anchor

scientific article published on 01 March 1992

Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats ⬇️

artículo científico publicado el 15 de septiembre de 1992

Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins

scientific article published on 01 June 2002

Folate status is the major determinant of fasting total plasma homocysteine levels in maintenance dialysis patients

artículo científico publicado en 1996

Folate synthesized by bacteria in the human upper small intestine is assimilated by the host

artículo científico publicado en 1996

Folate transport in isolated brush border membrane vesicles from rat intestine.

artículo científico publicado en 1981

Folate transport.

artículo científico publicado en 1985

Folate-binding protein and the absorption of folic acid in the small intestine of the suckling rat

scientific article published on 01 September 1988

Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency

artículo científico publicado en 2009

Folic acid fortification increases red blood cell folate concentrations in the Framingham study

artículo científico publicado en 2001

Folic acid fortification of the food supply. Potential benefits and risks for the elderly population

scientific article published on 01 December 1996

Folic acid fortification: why not vitamin B12 also?

artículo científico publicado en 2011

Folic acid intake from fortification in United States exceeds predictions

artículo científico publicado en 2002

Gastrointestinal absorption of folates and antifolates ⬇️

artículo científico publicado el 1 de enero de 1983

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke

artículo científico publicado en 2014

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway

artículo científico publicado en 2009

High Homocysteine Levels Are Independently Related to Isolated Systolic Hypertension in Older Adults ⬇️

artículo científico publicado el 16 de septiembre de 1997

High dose ascorbate supplementation fails to affect plasma homocyst(e)ine levels in patients with coronary heart disease

artículo científico publicado en 1994

High dose-B-vitamin treatment of hyperhomocysteinemia in dialysis patients

artículo científico publicado en 1996

High folic acid intake reduces natural killer cell cytotoxicity in aged mice

artículo científico publicado en 2016

High intake of folic acid disrupts embryonic development in mice ⬇️

artículo científico publicado el 22 de diciembre de 2010

High plasma folate is negatively associated with leukocyte telomere length in Framingham Offspring cohort

artículo científico publicado en 2014

High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial

artículo científico publicado en 2008

Homocysteine and arteriosclerosis: subclinical and clinical disease associations

artículo científico publicado en 1999

Homocysteine and cognitive performance in the Framingham offspring study: age is important

artículo científico publicado en 2005

Homocysteine and coronary artery disease in French Canadian subjects: relation with vitamins B12, B6, pyridoxal phosphate, and folate

artículo científico publicado en 1995

Homocysteine and its disulfide derivatives: a suggested consensus terminology

artículo científico publicado en 2000

Homocysteine as a predictive factor for hip fracture in older persons

artículo científico publicado en 2004

Homocysteine as a risk factor for coronary heart diseases and its association with inflammatory biomarkers, lipids and dietary factors

artículo científico publicado en 2004

Homocysteine in chronic kidney disease: Effect of low protein diet and repletion with B vitamins

artículo científico publicado en 2005

Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging

artículo científico publicado en 2002

Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women

scientific article published on 01 May 2005

Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging

artículo científico publicado en 2005

Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression

artículo científico publicado en 2002

Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial

artículo científico publicado en 2011

Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey

artículo científico publicado en 2001

Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey.

artículo científico publicado en 2001

Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice

artículo científico publicado en 2011

Hyperhomocysteinemia in renal transplant recipients

artículo científico publicado en 2002

Hyperhomocysteinemia, hyperfibrinogenemia, and lipoprotein (a) excess in maintenance dialysis patients: a matched case-control study

artículo científico publicado en 1996

In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific.

artículo científico publicado en 2002

In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations

artículo científico publicado en 2007

Inflammation causes tissue-specific depletion of vitamin B6.

artículo científico publicado en 2005

Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction

artículo científico publicado en 2001

Inhibition of Folate Enzymes by Sulfasalazine ⬇️

artículo científico publicado el 1 de enero de 1978

Interaction between excess folate and low vitamin B12 status

artículo científico publicado en 2016

Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism

artículo científico publicado en 1997

Intestinal absorption of biotin in the rat

artículo científico publicado en 1986

Intestinal transport of 5-methyltetrahydrofolate

artículo científico publicado en 1984

Investigating methotrexate toxicity within a randomized double-blinded, placebo-controlled trial: Rationale and design of the Cardiovascular Inflammation Reduction Trial-Adverse Events (CIRT-AE) Study

artículo científico publicado en 2017

Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model

artículo científico publicado en 2002

Kinetic analysis of the effect of luminal pH on transport of folic acid in the small intestine.

artículo científico publicado en 1989

Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop

artículo científico publicado en 2020

Lack of effect of oral N-acetylcysteine on the acute dialysis-related lowering of total plasma homocysteine in hemodialysis patients

artículo científico publicado en 1996

Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet

artículo científico publicado en 2006

Linkage disequilibrium between the 677C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer

artículo científico publicado en 2002

Low Plasma Vitamin B12 Is Associated With Lower BMD: The Framingham Osteoporosis Study

Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels

artículo científico publicado en 2001

Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study

artículo científico publicado en 2004

Low vitamin B12 increases risk of gastric cancer: A prospective study of one-carbon metabolism nutrients and risk of upper gastrointestinal tract cancer

artículo científico publicado en 2017

Lower fasting total plasma homocysteine levels in stable renal transplant recipients versus maintenance dialysis patients

artículo científico publicado en 1998

Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation

artículo científico

Metabolic syndrome in the elderly living in marginal peri-urban communities in Quito, Ecuador

artículo científico publicado en 2010

Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation

artículo científico publicado en 2003

Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes

artículo científico publicado en 2012

Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides

scientific article published on 01 March 2005

Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

artículo científico publicado en 1997

Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians

artículo científico publicado en 1996

Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates

artículo científico publicado en 2004

Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians

artículo científico publicado en 2009

Mild methionine excess does not affect thymidylate synthesis or inflammation markers expression in human aortic endothelial cells

artículo científico publicado en 2009

Moderately high intake of folic acid has a negative impact on mouse embryonic development

artículo científico publicado en 2012

Multimarker approach for the prediction of heart failure incidence in the community

artículo científico publicado en 2010

Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study

artículo científico publicado en 2008

Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study

artículo científico publicado en 2007

Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study

artículo científico publicado en 2012

Multiple biomarkers and the risk of incident hypertension

artículo científico publicado en 2007

Multiple biomarkers for the prediction of first major cardiovascular events and death

artículo científico publicado en 2006

Net uptake of plasma homocysteine by the rat kidney in vivo

scientific article published on 01 July 1995

Nonfasting Plasma Total Homocysteine Levels and Stroke Incidence in Elderly Persons: The Framingham Study

artículo científico publicado en 1999

Nonfasting plasma total homocysteine level and mortality in middle-aged and elderly men and women in Jerusalem.

artículo científico publicado en 1999

Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women

artículo científico publicado en 1999

Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid

artículo científico publicado en 2008

One-carbon metabolism biomarkers and risk of colon and rectal cancers

artículo científico publicado en 2008

Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women

artículo científico publicado en 2008

Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folic acid fortification in the US

artículo científico publicado en 2019

Plasma B-vitamins and one-carbon metabolites and the risk of breast cancer in younger women

artículo científico publicado en 2019

Plasma cysteinylglycine levels and breast cancer risk in women

artículo científico publicado en 2007

Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies

artículo científico publicado en 2012

Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women

scientific article published on 01 March 2008

Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer

artículo científico publicado en 2003

Plasma homocysteine and all-cause mortality in diabetes

artículo científico publicado en 1999

Plasma homocysteine and cysteine and risk of breast cancer in women

artículo científico publicado en 2010

Plasma homocysteine and parental myocardial infarction in young adults in Jerusalem

artículo científico publicado en 2002

Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction

artículo científico publicado en 2003

Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus

artículo científico publicado en 1996

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

artículo científico publicado en 2002

Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study

artículo científico publicado en 2003

Plasma pyridoxal 5'-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status

artículo científico publicado en 2003

Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004

artículo científico publicado en 2008

Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults

artículo científico publicado en 2012

Plasma total cysteine and total homocysteine and risk of myocardial infarction in women: a prospective study

artículo científico publicado en 2010

Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits

artículo científico publicado en 1996

Plasma total homocysteine levels among patients undergoing nocturnal versus standard hemodialysis

artículo científico publicado en 2002

Plasma total homocysteine levels in subjects with hyperinsulinemia

artículo científico publicado en 2000

Plasma vitamin B(6) and risk of myocardial infarction in women

artículo científico publicado en 2009

Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring Study

Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women

artículo científico publicado en 2005

Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer ⬇️

artículo científico publicado el 1 de octubre de 2003

Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.

artículo científico publicado en 2005

Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele

artículo científico publicado en 2015

Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study

artículo científico publicado en 2004

Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine: initial results from the NHLBI Family Heart Study.

artículo científico publicado en 1995

Power Shortage: clinical trials testing the "homocysteine hypothesis" against a background of folic acid-fortified cereal grain flour

artículo científico publicado en 2001

Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women

artículo científico publicado en 2013

Preconception folate and vitamin B(6) status and clinical spontaneous abortion in Chinese women

artículo científico publicado en 2002

Preconception homocysteine and B vitamin status and birth outcomes in Chinese women

artículo científico publicado en 2002

Prediagnostic plasma folate and the risk of death in patients with colorectal cancer

artículo científico publicado en 2008

Prediagnostic plasma vitamin B6 (pyridoxal 5'-phosphate) and survival in patients with colorectal cancer

scientific article published on 23 January 2013

Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis

artículo científico publicado en 2007

Prenatal folic acid use associated with decreased risk of myelomeningocele: A case-control study offers further support for folic acid fortification in Bangladesh

artículo científico publicado en 2017

Preparation and use of affinity columns with bovine milk folate-binding protein (FBP) covalently linked to Sepharose 4B

artículo científico publicado en 1980

Presence of circulating folic acid in plasma and its relation with dietary intake, vitamin B complex concentrations and genetic variants

artículo científico publicado en 2018

Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment

artículo científico publicado en 2012

Prevalence of mild fasting hyperhomocysteinemia in renal transplant versus coronary artery disease patients after fortification of cereal grain flour with folic acid

artículo científico publicado en 1999

Prospective study of plasma vitamin B6 and risk of colorectal cancer in men

artículo científico publicado en 2009

Prospective study of serum B vitamins levels and oesophageal and gastric cancers in China

artículo científico publicado en 2016

Prospective study of serum cysteine and cysteinylglycine and cancer of the head and neck, esophagus, and stomach in a cohort of male smokers

artículo científico publicado en 2016

Prospective study of serum cysteine levels and oesophageal and gastric cancers in China

artículo científico publicado en 2011

Proteinuria and plasma total homocysteine levels in chronic renal disease patients with a normal range serum creatinine: critical impact of true glomerular filtration rate

artículo científico publicado en 2001

Proteinuria as a predictor of total plasma homocysteine levels in type 2 diabetic nephropathy

artículo científico publicado en 2002

Public health significance of elevated homocysteine

artículo científico publicado en 2008

Public health significance of supplementation or fortification of grain products with folic acid

artículo científico publicado en 2008

Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis

artículo científico publicado en 2005

Rapid communication: L-folinic acid versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients

artículo científico publicado en 2001

Redox homeostasis in stomach medium by foods: The Postprandial Oxidative Stress Index (POSI) for balancing nutrition and human health

artículo científico publicado en 2017

Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase

artículo científico publicado en 2006

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

artículo científico publicado en 1996

Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans

artículo científico publicado en 2005

Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community

artículo científico publicado en 2010

Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study

artículo científico publicado en 2004

Relationship between homocysteine and mortality in chronic kidney disease

artículo científico publicado en 2006

Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification

artículo científico publicado en 2000

Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study population

artículo científico publicado en 1996

Renal insufficiency, vitamin B(12) status, and population attributable risk for mild hyperhomocysteinemia among coronary artery disease patients in the era of folic acid-fortified cereal grain flour

artículo científico publicado en 2001

Renal metabolism of homocysteine in vivo

scientific article published on 01 August 1995

Reply to Quinlivan: Postfortification, folate intake in vitamin B12 deficiency is positively related to homocysteine and methylmalonic acid.

artículo científico publicado en 2008

Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake

artículo científico publicado en 2012

Role of sodium ion in transport of folic acid in the small intestine

artículo científico publicado en 1986

Royal academy of medicine in Ireland international conference on homocysteine metabolism from basic science to clinical medicine

scientific article published in 1995

Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study

artículo científico publicado en 2010

Serum creatinine and prostate cancer risk in a prospective study

artículo científico publicado en 2009

Serum cystatin C as a determinant of fasting total homocysteine levels in renal transplant recipients with a normal serum creatinine.

artículo científico publicado en 1999

Serum cystatin C is an independent predictor of total homocysteine levels in stable Korean renal transplant recipients with normal serum creatinine.

artículo científico publicado en 2001

Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III

artículo científico publicado en 2000

Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey

artículo científico publicado en 1999

Serum total homocysteine concentrations in children and adolescents: results from the third National Health and Nutrition Examination Survey (NHANES III).

artículo científico publicado en 2003

Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations

artículo científico publicado en 1999

Short term betaine therapy fails to lower elevated fasting total plasma homocysteine concentrations in hemodialysis patients maintained on chronic folic acid supplementation

artículo científico publicado en 1995

Short-term reproducibility of total homocysteine determinations in stable renal transplant recipients

artículo científico publicado en 1999

Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults

artículo científico publicado en 2012

Sulfur amino acids and atherosclerosis: a role for excess dietary methionine.

artículo científico publicado en 2015

Telomere length in peripheral blood mononuclear cells is associated with folate status in men.

artículo científico publicado en 2009

The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine

artículo científico publicado en 2001

The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population.

artículo científico publicado en 2006

The association between vitamin B12, albuminuria and reduced kidney function: an observational cohort study

artículo científico publicado en 2015

The atherogenic effect of excess methionine intake

artículo científico publicado en 2003

The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice

artículo científico publicado en 2006

The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr

artículo científico publicado en 2002

The effect of N-acetylcysteine on plasma total homocysteine levels in hemodialysis: a randomized, controlled study

artículo científico publicado en 2003

The effect of folic acid fortification on plasma folate and total homocysteine concentrations

scientific article published on 01 May 1999

The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort

artículo científico publicado en 2002

The hydrolysis of nicotinamide adenine nucleotide by brush border membranes of rat intestine

artículo científico publicado en 1982

The kidney and homocysteine metabolism.

artículo científico publicado en 2001

The many facets of hyperhomocysteinemia: studies from the Framingham cohorts

artículo científico publicado en 2006

The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women

artículo científico publicado en 2005

The relation of plasma homocysteine to radiographic knee osteoarthritis

artículo científico publicado en 2008

The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.

artículo científico publicado en 2002

The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status

artículo científico publicado en 2008

Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey

artículo científico publicado en 2000

Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour

artículo científico publicado en 2002

Total plasma homocysteine and arteriosclerotic outcomes in type 2 diabetes with nephropathy

artículo científico publicado en 2005

Transcobalamin 776C→G polymorphism is associated with peripheral neuropathy in elderly individuals with high folate intake

artículo científico publicado en 2016

Treatment of hyperhomocysteinemia in end-stage renal disease.

artículo científico publicado en 2001

Treatment of hyperhomocysteinemia in hemodialysis patients and renal transplant recipients

artículo científico publicado en 2001

Treatment of hyperhomocysteinemia in renal transplant recipients. A randomized, placebo-controlled trial

artículo científico publicado en 1997

Treatment of mild hyperhomocysteinemia in renal transplant recipients versus hemodialysis patients

artículo científico publicado en 2000

Unmetabolized Folic Acid in Prediagnostic Plasma and the Risk of Colorectal Cancer

artículo científico publicado en 2015

Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women

artículo científico publicado en 2006

Uracil misincorporation into DNA and folic acid supplementation

artículo científico publicado en 2009

Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products

artículo científico publicado en 2006

Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium

artículo científico publicado en 1991

Validation of abbreviated oral methionine-loading test

artículo científico publicado en 1995

Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the framingham heart study

artículo científico publicado en 2012

Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium

artículo científico publicado en 2004

Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status

artículo científico publicado en 2009

Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

artículo científico publicado en 1993

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