Lista de obras -

A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene

artículo científico publicado en 2004

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

artículo científico publicado en 2016

Aging and longevity between genetic background and lifestyle intervention.

artículo científico publicado en 2014

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

artículo científico publicado en 2016

Anti-ageing and rejuvenating effects of quercetin

artículo científico publicado en 2010

Anti-ageing properties of Khelma Longevity™: treatment of human fibroblasts increases proteasome levels and decreases the levels of oxidized proteins

artículo científico publicado en 2017

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

artículo científico publicado en 2018

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

artículo científico

Beneficial Effects of Elderly Tailored Mediterranean Diet on the Proteasomal Proteolysis

artículo científico publicado en 2018

CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor ⬇️

artículo científico publicado el 27 de septiembre de 2011

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

artículo científico publicado en 2003

Chemical analysis of Greek pollen - Antioxidant, antimicrobial and proteasome activation properties.

artículo científico publicado en 2011

Cloning of differentially expressed genes in skin fibroblasts from centenarians

artículo científico publicado en 2004

Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

artículo científico publicado en 2015

Comparative effects of hypoxia on normal and immortalized human diploid fibroblasts

scientific article published on 01 May 2006

Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429]

article

Editorial

scientific article published on 14 September 2015

Exposure of human diploid fibroblasts to hypoxia extends proliferative life span

artículo científico publicado en 2007

Functional analysis of clusterin/apolipoprotein J in cellular death induced by severe genotoxic stress

artículo científico publicado en 2004

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

artículo científico publicado en 2019

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

artículo científico publicado en 2013

Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines

artículo científico publicado en 2010

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR.

artículo científico publicado en 2013

Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage

artículo científico publicado en 2017

Identification of differentially expressed proteins in senescent human embryonic fibroblasts

artículo científico publicado en 2005

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

artículo científico publicado en 2020

MARK-AGE biomarkers of ageing

artículo científico publicado en 2015

MARK-AGE population: From the human model to new insights

artículo científico publicado en 2015

Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals

artículo científico publicado en 2020

Mediterranean diet and inflammaging in the elderly: the European project NU-AGE. Preface

artículo científico publicado en 2014

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review

artículo científico

Microwave-assisted synthesis of 3,5-disubstituted isoxazoles and evaluation of their anti-ageing activity

artículo científico publicado en 2014

Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts

artículo científico publicado en 2010

Optimization of in vitro measurement of proteasome activity in mammalian cells using fluorogenic substrates

artículo científico publicado en 2014

Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging.

artículo científico publicado en 2018

Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide

artículo científico publicado en 2002

Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence

artículo científico publicado en 2007

Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates

scientific article published on 20 January 2005

Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status

artículo científico publicado en 2008

Pharmacological intervention in a transgenic mouse model improves Alzheimer's-associated pathological phenotype: involvement of proteasome activation

scientific article published on 03 December 2020

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries

artículo científico publicado en 2016

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

artículo científico publicado en 2019

Proteasome activation delays aging in vitro and in vivo

artículo científico publicado en 2014

Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells

artículo científico publicado en 2016

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases.

artículo científico

Proteasome dysfunction in mammalian aging: steps and factors involved

artículo científico publicado en 2005

Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures

artículo científico publicado en 2004

Proteasome response to interferon-gamma is altered in senescent human fibroblasts

scientific article published on 21 June 2006

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

artículo científico publicado en 2017

Protein damage, repair and proteolysis.

artículo científico publicado en 2012

Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems

artículo científico publicado en 2002

Protein modification and maintenance systems as biomarkers of ageing.

artículo científico publicado en 2015

Protein synthesis inhibition induces proteasome assembly and function

scientific article published on 24 April 2019

Quality control data of physiological and immunological biomarkers measured in serum and plasma

artículo científico publicado en 2015

Reduced expression levels of the senescence biomarker clusterin/apolipoprotein j in lymphocytes from healthy centenarians

artículo científico publicado en 2006

Report of Society for Free Radical Research Europe Summer School

artículo científico publicado en 2008

Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarction

artículo científico publicado en 2002

Signaling pathways of dietary energy restriction and metabolism on brain physiology and in age-related neurodegenerative diseases

artículo científico publicado en 2020

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

artículo científico publicado en 2004

Stress and Senescence: A Special Issue dedicated to Olivier Toussaint

artículo científico publicado en 2018

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

artículo científico publicado en 2013

The conundrum of human immune system "senescence"

scientific article published on 16 September 2020

The genetics of human longevity

artículo científico publicado en 2006

The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts

artículo científico publicado en 2007

The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression

scientific article published on 18 August 2009

Vitamin E-gene interactions in aging and inflammatory age-related diseases: implications for treatment. A systematic review

artículo científico

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

artículo científico publicado en 2005

What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians

artículo científico publicado en 2002

Where ageing goes nowadays: Mechanisms, pathways, biomarkers and anti-ageing strategies

artículo científico publicado en 2018

Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study.

artículo científico publicado en 2007

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project

artículo científico publicado en 2017

Lista de obras de

A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

Aging and longevity between genetic background and lifestyle intervention.

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

Anti-ageing and rejuvenating effects of quercetin

Anti-ageing properties of Khelma Longevity™: treatment of human fibroblasts increases proteasome levels and decreases the levels of oxidized proteins

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

Beneficial Effects of Elderly Tailored Mediterranean Diet on the Proteasomal Proteolysis

CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor ⬇️

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

Chemical analysis of Greek pollen - Antioxidant, antimicrobial and proteasome activation properties.

Cloning of differentially expressed genes in skin fibroblasts from centenarians

Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

Comparative effects of hypoxia on normal and immortalized human diploid fibroblasts

Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429]

Editorial

Exposure of human diploid fibroblasts to hypoxia extends proliferative life span

Functional analysis of clusterin/apolipoprotein J in cellular death induced by severe genotoxic stress

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR.

Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage

Identification of differentially expressed proteins in senescent human embryonic fibroblasts

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

MARK-AGE biomarkers of ageing

MARK-AGE population: From the human model to new insights

Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals

Mediterranean diet and inflammaging in the elderly: the European project NU-AGE. Preface

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review

Microwave-assisted synthesis of 3,5-disubstituted isoxazoles and evaluation of their anti-ageing activity

Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts

Optimization of in vitro measurement of proteasome activity in mammalian cells using fluorogenic substrates

Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging.

Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide

Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence

Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates

Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status

Pharmacological intervention in a transgenic mouse model improves Alzheimer's-associated pathological phenotype: involvement of proteasome activation

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

Proteasome activation delays aging in vitro and in vivo

Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases.

Proteasome dysfunction in mammalian aging: steps and factors involved

Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures

Proteasome response to interferon-gamma is altered in senescent human fibroblasts

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

Protein damage, repair and proteolysis.

Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems

Protein modification and maintenance systems as biomarkers of ageing.

Protein synthesis inhibition induces proteasome assembly and function

Quality control data of physiological and immunological biomarkers measured in serum and plasma

Reduced expression levels of the senescence biomarker clusterin/apolipoprotein j in lymphocytes from healthy centenarians

Report of Society for Free Radical Research Europe Summer School

Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarction

Signaling pathways of dietary energy restriction and metabolism on brain physiology and in age-related neurodegenerative diseases

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

Stress and Senescence: A Special Issue dedicated to Olivier Toussaint

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

The conundrum of human immune system "senescence"

The genetics of human longevity

The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts

The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression

Vitamin E-gene interactions in aging and inflammatory age-related diseases: implications for treatment. A systematic review

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians

Where ageing goes nowadays: Mechanisms, pathways, biomarkers and anti-ageing strategies

Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study.

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project