Lista de obras -

A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis

artículo científico publicado en 2019

A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development ⬇️

artículo científico publicado el 24 de enero de 2012

A strategy for in vitro propagation of rat nephrons

artículo científico publicado en 2002

Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct

artículo científico publicado en 2006

Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney

artículo científico publicado en 2005

Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].

artículo científico publicado en 2005

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling

artículo científico publicado en 2016

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members

artículo científico publicado en 2009

Analysis of metagene portraits reveals distinct transitions during kidney organogenesis

artículo científico publicado en 2008

Branching morphogenesis and kidney disease

artículo científico publicado en 2004

Branching morphogenesis: From individual molecules to a systems biology approachCommentary on “Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney” by Perälä et al ⬇️

artículo científico publicado el 17 de diciembre de 2010

Cellular and developmental strategies aimed at kidney tissue engineering

artículo científico publicado en 2014

Complex dynamics of chaperone-protein interactions under cellular stress

artículo científico publicado en 2004

Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.

artículo científico publicado en 2011

Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney

artículo científico publicado en 2010

Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis

artículo científico publicado en 2003

Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury

artículo científico publicado en 2011

Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues

artículo científico publicado en 2007

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).

artículo científico publicado en 2011

Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

artículo científico publicado en 2015

GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling

artículo científico publicado en 2013

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells

artículo científico publicado en 2015

Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct

artículo científico publicado en 2007

Growth factor-heparan sulfate "switches" regulating stages of branching morphogenesis

artículo científico

Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease

scientific article published on 09 April 2020

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

artículo científico publicado en 2015

Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters

artículo científico publicado en 2013

Heregulin induces glial cell line-derived neurotrophic growth factor-independent, non-branching growth and differentiation of ureteric bud epithelia

artículo científico publicado en 2005

How does the ureteric bud branch?

artículo científico publicado en 2008

Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy

scientific journal article

In Vitro Culture of Embryonic Kidney Rudiments and Isolated Ureteric Buds ⬇️

artículo científico publicado el 1 de enero de 2012

Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes

artículo científico

Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers

artículo científico publicado en 2016

MAPAS: a tool for predicting membrane-contacting protein surfaces

artículo científico publicado en 2008

Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease

artículo científico publicado en 2013

Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function

artículo científico publicado en 2008

Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach

artículo científico publicado en 2016

Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct

artículo científico publicado en 2009

Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule

artículo científico publicado en 2012

Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue ⬇️

artículo científico publicado el 27 de noviembre de 2012

Organogenesis forum lecture: In vitro kidney development, tissue engineering and systems biology

artículo científico publicado en 2008

Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct ⬇️

artículo científico publicado el 15 de septiembre de 2010

Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney

scientific journal article

Relevance of ureteric bud development and branching to tissue engineering, regeneration and repair in acute and chronic kidney disease

artículo científico

Rho kinase acts at separate steps in ureteric bud and metanephric mesenchyme morphogenesis during kidney development

artículo científico publicado en 2006

Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney

artículo científico publicado en 2004

TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud.

artículo científico publicado en 2004

The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

artículo científico publicado en 2020

The developmental nephrome: systems biology in the developing kidney

artículo científico publicado en 2007

The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis

artículo científico publicado en 2017

The effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: potential applications to engineering of renal tissues

scientific journal article

The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects

artículo científico publicado en 2009

The molecular pharmacology of organic anion transporters: from DNA to FDA?

artículo científico publicado en 2004

The systems biology of uric acid transporters: the role of remote sensing and signaling

scientific article published on 01 July 2018

Untargeted Metabolomics Identifies Enterobiome Metabolites and Putative Uremic Toxins as Substrates of Organic Anion Transporter 1 (Oat1) ⬇️

artículo científico publicado el 22 de abril de 2011

Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling

artículo científico publicado en 2019

Lista de obras de

A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis

A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development ⬇️

A strategy for in vitro propagation of rat nephrons

Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct

Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney

Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members

Analysis of metagene portraits reveals distinct transitions during kidney organogenesis

Branching morphogenesis and kidney disease

Branching morphogenesis: From individual molecules to a systems biology approachCommentary on “Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney” by Perälä et al ⬇️

Cellular and developmental strategies aimed at kidney tissue engineering

Complex dynamics of chaperone-protein interactions under cellular stress

Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.

Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney

Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis

Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury

Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).

Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells

Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct

Growth factor-heparan sulfate "switches" regulating stages of branching morphogenesis

Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters

Heregulin induces glial cell line-derived neurotrophic growth factor-independent, non-branching growth and differentiation of ureteric bud epithelia

How does the ureteric bud branch?

Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy

In Vitro Culture of Embryonic Kidney Rudiments and Isolated Ureteric Buds ⬇️

Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes

Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers

MAPAS: a tool for predicting membrane-contacting protein surfaces

Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease

Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function

Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach

Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct

Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule

Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue ⬇️

Organogenesis forum lecture: In vitro kidney development, tissue engineering and systems biology

Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct ⬇️

Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney

Relevance of ureteric bud development and branching to tissue engineering, regeneration and repair in acute and chronic kidney disease

Rho kinase acts at separate steps in ureteric bud and metanephric mesenchyme morphogenesis during kidney development

Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney

TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud.

The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

The developmental nephrome: systems biology in the developing kidney

The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis

The effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: potential applications to engineering of renal tissues

The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects

The molecular pharmacology of organic anion transporters: from DNA to FDA?

The systems biology of uric acid transporters: the role of remote sensing and signaling

Untargeted Metabolomics Identifies Enterobiome Metabolites and Putative Uremic Toxins as Substrates of Organic Anion Transporter 1 (Oat1) ⬇️

Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling